Database Description
| General information of database | |
Database name
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D-HaploDB
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Alternative name
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Definitive Haplotype Database |
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DOI
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10.18908/lsdba.nbdc00036-000 |
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Creator
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Creator Name
Kenshi Hayashi*
Creator Affiliation
Research Center for Genetic Information, Medical Institute of Bioregulation, Kyushu University
Creator Name
Tomoko Tahira
Creator Affiliation
Research Center for Genetic Information, Medical Institute of Bioregulation, Kyushu University
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Contact address
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Tomoko Tahira |
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Database classification
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Human Genes and Diseases - General polymorphism databases |
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Organism
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Database description
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This database presents true haplotypes and LD structures of Japanese genome, determined using DNA samples obtained from complete hydatidiform moles. |
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Features and manner of utilization of database
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The genome of complete hydatidiform mole is derived from a single sperm. Therefore, the haplotypes described in DHaploDB are true haplotypes. This is in contrast to the haplotypes of Asians described by the HapMap Project, which are haplotypes deduced from genotypes of diploid materials using computational method that yields haplotypes with error at a certain level. G-browse function is implemented at the original website (see below), where updated version (D4) is available. |
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License
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CC BY-SA Detail |
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Background and funding
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Name
"Research Revolution 2002" (RR2002) initiative from the Ministry of Education, Culture, Sports, Science and Technology, Japan.
Name
A Grant-in-Aid for Scientific Research on Priority Areas “Applied Genomics" from the Ministry of Education, Culture, Sports, Science and Technology, Japan.  |
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Reference(s)
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Article title
Genome-wide definitive haplotypes determined using a collection of complete hydatidiform moles.
Author name(s)
Kukita Y, Miyatake K, Stokowski R, Hinds D, Higasa K, Wake N, Hirakawa T, Kato H, Matsuda T, Pant K, Cox D, Tahira T, Hayashi K.
Journal
Genome Res. 2005 Nov;15(11):1511-8.
External Links
Article title
D-HaploDB: a database of definitive haplotypes determined by genotyping complete hydatidiform mole samples.
Author name(s)
Higasa K, Miyatake K, Kukita Y, Tahira T, Hayashi K.
Journal
Nucleic Acids Res. 2007 Jan;35(Database issue):D685-9.
External Links
Article title
Evaluation of haplotype inference using definitive haplotype data obtained from complete hydatidiform moles, and its significance for the analyses of positively selected regions.
Author name(s)
Higasa K, Kukita Y, Kato K, Wake N, Tahira T, Hayashi K.
Journal
PLoS Genetics, 2009 May;5(5):e1000468.
External Links
Article title
A definitive haplotype map as determined by genotyping duplicated haploid genomes finds a predominant haplotype preference at copy-number variation events.
Author name(s)
Kukita Y, Yahara K, Tahira T, Higasa K, Sonoda M, Yamamoto K, Kato K, Wake N, Hayashi K.
Journal
Am. J. Hum. Genet. 2010 Jun;86(6):918-28.
External Links
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| Original website information | |
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Database maintenance site
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Division of Genome Analysis,Research Center for Genetic Information, Medical Institute of Bioregulation, Kyushu University |
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URL of the original website
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(Closed)http://orca.gen.kyushu-u.ac.jp/ |
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Operation start date
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2005/7/20 |
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Last update date
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2011/6/23 |
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URL of the portal site
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http://www.gen.kyushu-u.ac.jp/~genome/database.html |
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Whole data download
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(Closed)http://orca.gen.kyushu-u.ac.jp/download.html |
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Referenced database
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- |
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Entry list
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Not available |
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Query search
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Not available |
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Web services
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Not available |
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URL of Web services
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- |
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Need for user registration
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Not available |
