The Trypanosomes database is a database providing the comprehensive information of proteins that is effective targets for drug development that can control trypanosomiasis. Trypanosome is a parasitic protozoan of the genus Trypanosoma that infects a variety of hosts and causes various diseases, including African sleeping sickness and South American chagas disease, that is, trypanosomiasis. Every year more than 100 thousands of people suffer from trypanosomiasis. It also infects livestock, and more than 100 thousands of cattle have died per year. So far, it has been found effective targets for drug development that can control trypanosomiasis. One of such targets is a group of enzymes that control trypanosome DNA/RNA biosynthetic pathway. Another target is a group of enzymes that control trypanosome oxidation/reduction pathway. Actually, in case of trypanosomes, these enzymes are involved in both reaction pathways, and greatly affect lives of trypanosomes.