Data item | Description |
BARCODE |
Bar-code assigned to each GeneChip in order to indentify. Bar-code matches CEL file name without extension. Data with the value "No ChipData" don't have a corresponding CEL file since the microarray gene expression analysis wasn't performed. |
ARR_DESIGN |
In the project, HG-U133_Plus_2 was used for human and Rat230_2 was used for rat. |
EXP_ID |
ID assigned to each test which can be indentified by a combination of COMPOUND_NAME, SPECIES, EXP_TEST_TYPE, and SINGLE_REPEAT_TYPE. IDs for in vivo tests are assigned from #0040. IDs for in vitro tests are assigned from #5000. |
GROUP_ID |
ID assigned to each group which can be indentified by a combination of DOSE_LEVEL and SACRIFICE_PERIOD. IDs are in double digits. (e.g. 01, 16) |
INDIVIDUAL_ID |
ID assigned to each individual within a group. IDs are in single digit. |
ORGAN |
Organ evaluated in tests. Liver or Kidney. |
MATERIAL_ID |
ID assigned to each tissue section which was used to acquire gene expression data. IDs are in a single letter. |
COMPOUND_NAME |
Compound name |
COMPOUND_ABBREVIATION |
Abbreviated compound name |
COMPOUND_NO |
Number assigned to each compound. Numbers are not in serial order. |
SPECIES |
Species |
EXP_TEST_TYPE |
Type of test. In vivo test or in vitro test. |
SINGLE_REPEAT_TYPE |
Type of in vivo test. Single-dose test or 28-day repeat-dose test. |
SEX_TYPE |
Gender. Male or Female. |
STRAIN_TYPE |
Rat strain used with in vivo tests |
ADMINISTRATION_ROUTE_TYPE |
Administration route |
ANIMAL_AGE(week) |
Age of animal (weeks). Only rats at 6 weeks of age were used. |
SACRIFICE_PERIOD |
Sampling time or period. |
DOSE |
Dose |
DOSE_UNIT |
Unit of dose |
DOSE_LEVEL |
Dose level. The ascending order of the levels is Control, Low, Middle, High. |
Organ Weight |
TERMINAL_BW(g) |
terminal body weight |
LIVER(g) |
the weight of the liver |
KIDNEY_TOTAL(g) |
the total weight of the kidneys |
KIDNEY_R(g) |
the weight of the right kidney |
KIDNEY_L(g) |
the weight of the left kidney |
Hematology |
RBC(x10_4/ul) |
red blood cell count |
Hb(g/dL) |
hemoglobin |
Ht(%) |
hematocrit value |
MCV(fL) |
mean corpuscular volume |
MCH(pg) |
mean corpuscular hemoglobin |
MCHC(%) |
mean corpuscular hemoglobin concentration |
Ret(%) |
reticulocyte |
Plat(x10_4/uL) |
platelet count |
WBC(x10_2/uL) |
white blood cell count |
Neu(%) |
neutrophil |
Eos(%) |
eosinophil |
Bas(%) |
basophil |
Mono(%) |
monocyte |
Lym(%) |
lymphocyte |
PT(s) |
prothrombin time |
APTT(s) |
activated partial thromboplastin time |
Fbg(mg/dL) |
fibrinogen |
Biochemistry |
ALP(IU/L) |
alkaline phosphatase |
TC(mg/dL) |
total cholesterol |
TG(mg/dL) |
triglyceride |
PL(mg/dL) |
phospholipid |
TBIL(mg/dL) |
total bilirubin |
DBIL(mg/dL) |
direct bilirubin |
GLC(mg/dL) |
glucose |
BUN(mg/dL) |
blood urea nitrogen |
CRE(mg/dL) |
creatinine |
Na(meq/L) |
sodium |
K(meq/L) |
potassium |
Cl(meq/L) |
chlorine |
Ca(mg/dL) |
calcium |
IP(mg/dL) |
inorganic phosphorus |
TP(g/dL) |
total protein |
RALB(g/dL) |
albumin |
A/G |
albumin globulin ratio |
AST(IU/L) |
aspartate aminotransferase |
ALT(IU/L) |
alanine aminotransferase |
LDH(IU/L) |
lactate dehydrogenase |
GTP(IU/L) |
γ-glutamyltranspeptidase |
Cell viability |
DNA(%) |
Relative survival rate calculated from DNA content. |
LDH(%) |
Relative survival rate calculated from the activity value of lactate dehydrogenase which is leaked in the culture supernatant. |