[ Japanese | English ]
CREATE portal
About This Database

Database Description

General information of database
Database name
CREATE portal
Alternative name
-
DOI
10.18908/lsdba.nbdc00403-000
Creator
Creator Name
Hisashi Koga
Creator Affiliation
Kazusa DNA Research Institute (KDRI)
Literature Search
Contact address
2-6-7 Kazusa-Kamatari, Kisarazu, Chiba 292-0818, Japan Kazusa DNA Research Institute
Database classification

Proteomics Resources

Organism
Taxonomy Name
Mus musculus
Taxonomy ID
Database description

KDRI has cloned ~2000 mouse homologs of human KIAA genes and prepared ~2000 rabbit polyclonal antibodies against respective mouse KIAA (mKIAA) proteins. In the CREATE portal, you can see the results of experiments exploring the expression levels of mRNA and protein for 274 mKIAA genes in the InGaP database. You can also see the results of protein-protein interaction of 50 mKIAA proteins of which interaction interactions were identified by mass spectrometry analysis following immuno-precipitation with anti-mKIAA antibodies.

Features and manner of utilization of database

You can see the results of tissue-specific expression of mKIAA proteins. These data are useful to find out the sensitivity and specificity of the anti-mKIAA antibodies, because parts of anti-mKIAA antibodies prepared in the project can be obtained from the ProteinExpress. In the InCeP database, you can see protein-protein interaction data of mKIAA proteins, useful to predict their functions.

License
CC BY-SA Detail
Background and funding
CREATE Program (Collaboration of Regional Entities for the Advancement of Techno- logical Excellence)  (2001-2006)
Reference(s)
Article title
A comprehensive approach for establishment of the platform to analyze functions of KIAA proteins II: public release of inaugural version of InGaP database containing gene/protein expression profiles for 127 mouse KIAA genes/proteins
Author name(s)
Koga H, Yuasa S, Nagase T, Shimada K, Nagano M, Imai K, Ohara R, Nakajima D, Murakami M, Kawai M, Miki F, Magae J, Inamoto S, Okazaki N, Ohara O.
Journal
DNA Res. 2004 Aug 31;11(4):293-304.
External Links
Article title
InCeP: intracellular pathway based on mKIAA protein-protein interactions
Author name(s)
Murakami M, Shimada K, Kawai M, Koga H.
Journal
DNA Res. 2005;12(5):379-87.
External Links
Original website information
Database maintenance site

-

URL of the original website
-
Operation start date
-
Last update date
-
URL of the portal site
-
Whole data download
-
Referenced database

-

Entry list
Not available
Query search
Not available
Web services
Not available
URL of Web services
-
Need for user registration
Not available