The Trypanosomes database is a database providing the comprehensive information of proteins that is effective targets for drug development that can control trypanosomiasis. Trypanosome is a parasitic protozoan of the genus Trypanosoma that infects a variety of hosts and causes various diseases, including African sleeping sickness and South American chagas disease, that is, trypanosomiasis. Every year more than 100 thousands of people suffer from trypanosomiasis. It also infects livestock, and more than 100 thousands of cattle have died per year. So far, it has been found effective targets for drug development that can control trypanosomiasis. One of such targets is a group of enzymes that control trypanosome DNA/RNA biosynthetic pathway. Another target is a group of enzymes that control trypanosome oxidation/reduction pathway. Actually, in case of trypanosomes, these enzymes are involved in both reaction pathways, and greatly affect lives of trypanosomes.

AT Atlas will make you familiar with the accomplishments by research groups of "Protein Production", "Structural Analysis" and "Chemical Regulation" in the Targeted Proteins Research Program. AT Atlas is composed of graphical abstract (flow chart) , information in text including actual application of the method and link to PRotein Experimental Information Management System (PREIMS). You will be able to find experimental methods used to elucidate the structure and/or functions of proteins that you are interested in. Further, you will be able to reproduce the experimental process to study corresponding entries of PREIMS. (Most of the graphical abstracts have been drawn by use of Cell Illustrator that is a pathway-drawing software developed by Prof. Satoru Miyano and his colleagues at the U. Tokyo)

This database contains information on the rice mitochondrial genome. You can refer entire sequence of rice mitochondrial genome and information on the analysis results.