Data item | Description |
Bait ORF |
The ORF name of Bait, and the systematic name in the SGD (Saccharomyces Genome Database;http://www.yeastgenome.org/). |
Bait gene name |
The gene name of Bait, and the standard name in the SGD. |
Bait description |
The annotation of Bait, and description in the SGD. |
Rows with this bait as bait |
The number of rows (interactions) having this Bait ORF as the Bait ORF, and the link to the search results (for TogoDB only). |
Rows with this bait as prey |
The number of rows (interactions) having this Bait ORF as the Prey ORF, and the link to the search results (for TogoDB only). |
Prey ORF |
The ORF name of Prey, and the systematic name in the SGD (Saccharomyces Genome Database;http://www.yeastgenome.org). |
Prey gene name |
The gene name of Prey, and the standard name in the SGD. |
Prey description |
The annotation of Prey, and description in the SGD. |
Rows with this prey as prey |
The number of rows (interactions) having this Prey ORF as the Prey ORF, and the link to the search results (for TogoDB only). |
Rows with this prey as bait |
The number of rows (interactions) having this Prey ORF as the Bait ORF, and the link to the search results (for TogoDB only). |
Literature on bait(YPD) |
The number of articles concerning Bait, obtained from YPD (Yeast Proteome Database)(*2). |
Literature on prey(YPD) |
The number of articles concerning Prey, obtained from YPD. |
Literature shared by bait and prey |
The number of articles common to Bait and Prey, as calculated on the basis of the number of articles obtained from the YPD. |
Literature sharing score |
The score concerning co-occurrence of Prey and Bait in the literature, calculated by the calculation formula. Calculation formula for the score:
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CuraGen(0 or 1) |
Investigation by CuraGen (0 or 1), obtained from Uetz et al.(*3) |
S. Fields(0 or 1) |
Investigation by S. Fields (0 or 1), obtained from Uetz et al. |
Association(0 or 1,YPD) |
Association (0 or 1), obtained from the YPD. |
Complex (0 or 1,YPD) |
Formation of complex (0 or 1), obtained from the YPD. |
Synthetic lethality(0 or 1,YPD) |
Synthetic lethality (0 or 1), obtained from the YPD. |
Co-induced by(YPD) |
Factor that induces expression of both genes, obtained from the YPD. |
Co-repressed by(YPD) |
Factor that suppresses expression of both genes, obtained from the YPD. |
Not affected by(YPD) |
Factor that does not affect expression of these genes, obtained from the YPD. |
Interologs |
The number of interactions that exist between the interacting protein and the ortholog of other species, obtained from the Database of Interacting Proteins(*4). |
Expression similarity (BRITE) |
Expression data obtained from KEGG BRITE(*5). (High values only, 0.9 or greater) |
Alternative path with 1 intervening protein |
The number of paths other than this interaction mediated by one intermediate protein, calculated from the full data. |
Alternative path with 2 intervening proteins |
The number of paths other than this interaction mediated by two intermediate proteins, calculated from the full data. |
IST hit |
Number of hits of Interaction Sequence Tags (IST) (The number of detected interactions and the indicator of reproducibility) |
IST hit in the opposite bait/prey orientation |
The IST hit number for a combination in which Bait and Prey are in the reverse direction. |
*1 A comprehensive two-hybrid analysis to explore the yeast protein interactome., Costanzo MC, Hogan JD, Cusick ME, Davis BP, Fancher AM, Hodges PE, Kondu P, Lengieza C, Lew-Smith JE, Lingner C, Roberg-Perez KJ, Tillberg M, Brooks JE, Garrels JI., Nucleic Acids Res. 2000 Jan 1;28(1):73-6. *2 The yeast proteome database (YPD) and Caenorhabditis elegans proteome database (WormPD): comprehensive resources for the organization and comparison of model organism protein information., Costanzo MC, Hogan JD, Cusick ME, Davis BP, Fancher AM, Hodges PE, Kondu P, Lengieza C, Lew-Smith JE, Lingner C, Roberg-Perez KJ, Tillberg M, Brooks JE, Garrels JI., Nucleic Acids Res. 2000 Jan 1;28(1):73-6. *3 A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae., Uetz P, Giot L, Cagney G, Mansfield TA, Judson RS, Knight JR, Lockshon D, Narayan V, Srinivasan M, Pochart P, Qureshi-Emili A, Li Y, Godwin B, Conover D, Kalbfleisch T, Vijayadamodar G, Yang M, Johnston M, Fields S, Rothberg JM., Nature. 2000 Feb 10;403(6770):623-7. *4 DIP: the database of interacting proteins., Xenarios I, Rice DW, Salwinski L, Baron MK, Marcotte EM, Eisenberg D., Nucleic Acids Res. 2000 Jan 1;28(1):289-91. *5 KEGG: kyoto encyclopedia of genes and genomes., Kanehisa M, Goto S., Nucleic Acids Res. 2000 Jan 1;28(1):27-30.
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