General information of database
|Toxicogenomics Informatics Project|
National Institute of Biomedical Innovation
7-6-8, Saito-asagi, Ibaraki-city, Osaka 567-0085, Japan
Toxicogenomics Project (TGP) is a government-private companies collaborative project started by the National Institute of Biomedical, the National Institute of Health Sciences, and 15 pharmaceutical companies in 2002. After 5 years of the project, 150 chemicals were administered to rats or exposed to rat and human primary cultured hepatocytes, and the gene expression profiles in the liver and kidney of the animal or in the cultured cells were comprehensively analyzed by microarray. As a result, a high-quality large-scale toxicogenomics database with the systems to analyze the gene expression data and predict the safety of candidate chemicals has been developed (TG-GATEs: Toxicogenomics Project-Genomics Assisted Toxicity Evaluation system）.
Searching toxicogenomics data by compound name or pathological finding.
Original website information
Toxicogenomics Informatics Project, National Institute of Biomedical Innovation