| PAX6's Target genes |
|
◢ PAX6: Average |
| ◢ SRX2203276: EndoC-BH1 |
◢ SRX2203277: EndoC-BH1 |
◢ SRX702056: hESC derived ectodermal cells |
◣ SRX702055: hESC derived mesendodermal cells |
| ◢ PAX6: STRING |
| MAMDC2 |
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| METTL11B |
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| ERRFI1 |
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| SERINC5 |
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| ZNF608 |
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| DPPA5 |
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| MFSD4B |
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| TMPRSS11E |
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| POU5F1 |
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| KIAA0895 |
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| REV3L |
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| TNNI3K |
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| RGPD2 |
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| RGPD1 |
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| TUBB2A |
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| REST |
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| CBR4 |
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| ATG16L1 |
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| TRIM2 |
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| HIGD1A |
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| ACKR2 |
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| SPEN |
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| KLHL7 |
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| MTRNR2L2 |
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| MSH3 |
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| DHFR |
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| AFAP1 |
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| MTRNR2L8 |
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| LOC102724770 |
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| DGCR6 |
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| DUX4 |
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| KIF12 |
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| FRG2C |
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| RGS4 |
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| IMP4 |
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| CCDC115 |
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| IZUMO2 |
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| SIRT4 |
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| FRG2 |
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| DAP |
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| PERCC1 |
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| C16orf91 |
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| ZFP64 |
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| FFAR3 |
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| FFAR1 |
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| MBD1 |
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| CXXC1 |
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| TAOK1 |
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| WDR74 |
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| STX5 |
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| MPP5 |
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| TMCO1 |
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| UNC5CL |
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| TSPO2 |
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| APOBEC2 |
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| MUC3A |
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| RASGEF1B |
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| SNU13 |
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| BCAR3 |
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| FGF14 |
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| PRSS22 |
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| CBFA2T2 |
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| CEP63 |
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| ANAPC13 |
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| COL21A1 |
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| GPR61 |
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| CDH4 |
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| ZSCAN20 |
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| FAM72D |
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| FAM72C |
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| ASH1L |
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| RASSF8 |
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| TMEM242 |
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| TXNDC9 |
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| EIF5B |
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| ZNF804A |
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| VRK1 |
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| GIPC2 |
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| SNX16 |
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| ATL1 |
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| MOB1A |
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| TAGAP |
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| TPH2 |
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| KLHDC7A |
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| NRG1 |
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| CACNG5 |
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| LDB3 |
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| TMEM88 |
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| NAA38 |
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| MXRA7 |
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| CYB5D1 |
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| PHC2 |
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| HSD17B1 |
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| RGP1 |
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| MSMP |
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| GBA2 |
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| FAM72B |
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| CFAP45 |
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| EBPL |
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| PKLR |
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| FDPS |
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| DYNC2I2 |
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| PTPN18 |
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| IRF2BPL |
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| ELK4 |
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| SYT7 |
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| PHLDA1 |
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| WEE1 |
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| SLC39A1 |
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| RAB13 |
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| JTB |
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| FOXP4 |
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| CREB3L4 |
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| ABLIM1 |
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| ZNF821 |
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| GC |
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| CSDE1 |
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| DAGLB |
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| BCL2L1 |
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| MTERF4 |
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| UBN1 |
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| GLYR1 |
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| RSBN1L |
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| SH3PXD2A |
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| STK19 |
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| MAP2 |
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| LOC110384692 |
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| DXO |
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| C4B |
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| C4B_2 |
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| C4A |
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| NOTCH2NLC |
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| NOTCH2NLB |
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| NOTCH2NLA |
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| DGKE |
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| C17orf67 |
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| SLC37A4 |
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| LOC102723996 |
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| ICOSLG |
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| DMBT1 |
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| MTRNR2L1 |
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| SLAMF8 |
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| SELENOF |
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| RHOBTB1 |
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| PCED1B |
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| HS2ST1 |
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| AMIGO2 |
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| CCDC200 |
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| SCAND1 |
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| TCF4 |
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| SETDB2-PHF11 |
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| SETDB2 |
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| CAB39L |
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| TRIM56 |
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| GET3 |
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| GBP6 |
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| CD93 |
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| IVD |
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| INAVA |
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| TMEM126B |
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| DLG2 |
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| GCK |
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| PRUNE1 |
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| MINDY1 |
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| GRPEL2 |
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| CRNKL1 |
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| CFAP61 |
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| ZNF317 |
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| RIC8B |
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| MTMR1 |
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| SLC44A5 |
↻ |
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| BRD4 |
↻ |
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| FGF1 |
↻ |
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| CTBS |
↻ |
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| MYT1 |
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| SPTAN1 |
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| BRINP3 |
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| CD164 |
↻ |
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| SPINK1 |
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| ELF5 |
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| KCNMB2 |
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| PIGC |
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| C1orf105 |
↻ |
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| CRLF3 |
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| ATAD5 |
↻ |
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| OTOGL |
↻ |
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| L2HGDH |
↻ |
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| DMAC2L |
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| SLC25A47 |
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| GSTT4 |
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| CABIN1 |
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| TNFSF4 |
↻ |
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| PDZK1 |
↻ |
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| C22orf34 |
↻ |
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| QSOX1 |
↻ |
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| MACC1 |
↻ |
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| LONP2 |
↻ |
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| ABCC11 |
↻ |
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| USP40 |
↻ |
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| SPEF1 |
↻ |
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≫ |
| PIK3IP1 |
↻ |
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≫ |
| CENPB |
↻ |
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≫ |
| CDC25B |
↻ |
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≫ |
| C20orf27 |
↻ |
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≫ |
| ATP10D |
↻ |
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≫ |
| SCG5 |
↻ |
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≫ |
| KCNK16 |
↻ |
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≫ |
| UPF3A |
↻ |
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≫ |
| MAB21L4 |
↻ |
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≫ |
| CROCC2 |
↻ |
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|
|
≫ |
| HSCB |
↻ |
|
|
|
|
|
|
|
≫ |
| CHEK2 |
↻ |
|
|
|
|
|
|
|
≫ |
| SLC6A19 |
↻ |
|
|
|
|
|
|
|
≫ |
| COX7A2L |
↻ |
|
|
|
|
|
|
|
≫ |
| GLYCTK |
↻ |
|
|
|
|
|
|
|
≫ |
| ASIC2 |
↻ |
|
|
|
|
|
|
|
≫ |
| KIF19 |
↻ |
|
|
|
|
|
|
|
≫ |
| ARL4D |
↻ |
|
|
|
|
|
|
|
≫ |
| PPP2R5A |
↻ |
|
|
|
|
|
|
|
≫ |
| KCTD17 |
↻ |
|
|
|
|
|
|
|
≫ |
| PDE4DIP |
↻ |
|
|
|
|
|
|
|
≫ |
| RMDN1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CPNE3 |
↻ |
|
|
|
|
|
|
|
≫ |
| DLD |
↻ |
|
|
|
|
|
|
|
≫ |
| AQP9 |
↻ |
|
|
|
|
|
|
|
≫ |
| MYH7 |
↻ |
|
|
|
|
|
|
|
≫ |
| CHRFAM7A |
↻ |
|
|
|
|
|
|
|
≫ |
| ARHGEF18 |
↻ |
|
|
|
|
|
|
|
≫ |
| PKDCC |
↻ |
|
|
|
|
|
|
|
≫ |
| ZADH2 |
↻ |
|
|
|
|
|
|
|
≫ |
| TSHZ1 |
↻ |
|
|
|
|
|
|
|
≫ |
| TSPAN2 |
↻ |
|
|
|
|
|
|
|
≫ |
| HOPX |
↻ |
|
|
|
|
|
|
|
≫ |
| UQCRH |
↻ |
|
|
|
|
|
|
|
≫ |
| LRRC41 |
↻ |
|
|
|
|
|
|
|
≫ |
| SH3GLB2 |
↻ |
|
|
|
|
|
|
|
≫ |
| FIGNL2 |
↻ |
|
|
|
|
|
|
|
≫ |
| RGL3 |
↻ |
|
|
|
|
|
|
|
≫ |
| UBR2 |
↻ |
|
|
|
|
|
|
|
≫ |
| TAGLN3 |
↻ |
|
|
|
|
|
|
|
≫ |
| SSTR5 |
↻ |
|
|
|
|
|
|
|
≫ |
| INPP4B |
↻ |
|
|
|
|
|
|
|
≫ |
| PLCXD3 |
↻ |
|
|
|
|
|
|
|
≫ |
| SLC35C2 |
↻ |
|
|
|
|
|
|
|
≫ |
| JUP |
↻ |
|
|
|
|
|
|
|
≫ |
| USP54 |
↻ |
|
|
|
|
|
|
|
≫ |
| TMEM217 |
↻ |
|
|
|
|
|
|
|
≫ |
| TBC1D22B |
↻ |
|
|
|
|
|
|
|
≫ |
| MED1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CDK12 |
↻ |
|
|
|
|
|
|
|
≫ |
| TMOD3 |
↻ |
|
|
|
|
|
|
|
≫ |
| CCDC33 |
↻ |
|
|
|
|
|
|
|
≫ |
| ANK2 |
↻ |
|
|
|
|
|
|
|
≫ |
| XPR1 |
↻ |
|
|
|
|
|
|
|
≫ |
| GTF3C4 |
↻ |
|
|
|
|
|
|
|
≫ |
| DDX31 |
↻ |
|
|
|
|
|
|
|
≫ |
| SPA17 |
↻ |
|
|
|
|
|
|
|
≫ |
| SIAE |
↻ |
|
|
|
|
|
|
|
≫ |
| MSANTD1 |
↻ |
|
|
|
|
|
|
|
≫ |
| MAPRE1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CLDN10 |
↻ |
|
|
|
|
|
|
|
≫ |
| EPAS1 |
↻ |
|
|
|
|
|
|
|
≫ |
| ADGRL2 |
↻ |
|
|
|
|
|
|
|
≫ |
| CYSTM1 |
↻ |
|
|
|
|
|
|
|
≫ |
| FARP2 |
↻ |
|
|
|
|
|
|
|
≫ |
| ITPR1 |
↻ |
|
|
|
|
|
|
|
≫ |
| RAB11FIP5 |
↻ |
|
|
|
|
|
|
|
≫ |
| HMGCR |
↻ |
|
|
|
|
|
|
|
≫ |
| TRMT10A |
↻ |
|
|
|
|
|
|
|
≫ |
| TIGD1 |
↻ |
|
|
|
|
|
|
|
≫ |
| SEMA4B |
↻ |
|
|
|
|
|
|
|
≫ |
| MTTP |
↻ |
|
|
|
|
|
|
|
≫ |
| EIF4E2 |
↻ |
|
|
|
|
|
|
|
≫ |
| OIP5 |
↻ |
|
|
|
|
|
|
|
≫ |
| NUSAP1 |
↻ |
|
|
|
|
|
|
|
≫ |
| SP1 |
↻ |
|
|
|
|
|
|
|
≫ |
| ZBTB40 |
↻ |
|
|
|
|
|
|
|
≫ |
| TOMM40 |
↻ |
|
|
|
|
|
|
|
≫ |
| TBCC |
↻ |
|
|
|
|
|
|
|
≫ |
| CASR |
↻ |
|
|
|
|
|
|
|
≫ |
| BICRAL |
↻ |
|
|
|
|
|
|
|
≫ |
| TLE6 |
↻ |
|
|
|
|
|
|
|
≫ |
| DENND2A |
↻ |
|
|
|
|
|
|
|
≫ |
| NOS1AP |
↻ |
|
|
|
|
|
|
|
≫ |
| TSSC4 |
↻ |
|
|
|
|
|
|
|
≫ |
| SRSF4 |
↻ |
|
|
|
|
|
|
|
≫ |
| TEAD1 |
↻ |
|
|
|
|
|
|
|
≫ |
| USE1 |
↻ |
|
|
|
|
|
|
|
≫ |
| RIF1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CDC42EP2 |
↻ |
|
|
|
|
|
|
|
≫ |
| BCAS1 |
↻ |
|
|
|
|
|
|
|
≫ |
| ATP5MG |
↻ |
|
|
|
|
|
|
|
≫ |
| SH3BP4 |
↻ |
|
|
|
|
|
|
|
≫ |
| GTPBP8 |
↻ |
|
|
|
|
|
|
|
≫ |
| RAB27A |
↻ |
|
|
|
|
|
|
|
≫ |
| GAD2 |
↻ |
|
|
|
|
|
|
|
≫ |
| HSPBP1 |
↻ |
|
|
|
|
|
|
|
≫ |
| BRSK1 |
↻ |
|
|
|
|
|
|
|
≫ |
| ZCCHC17 |
↻ |
|
|
|
|
|
|
|
≫ |
| SNRNP40 |
↻ |
|
|
|
|
|
|
|
≫ |
| METTL25 |
↻ |
|
|
|
|
|
|
|
≫ |
| LDLRAP1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CCDC59 |
↻ |
|
|
|
|
|
|
|
≫ |
| LFNG |
↻ |
|
|
|
|
|
|
|
≫ |
| RMI2 |
↻ |
|
|
|
|
|
|
|
≫ |
| HJURP |
↻ |
|
|
|
|
|
|
|
≫ |
| SMC4 |
↻ |
|
|
|
|
|
|
|
≫ |
| IFT80 |
↻ |
|
|
|
|
|
|
|
≫ |
| WDR82 |
↻ |
|
|
|
|
|
|
|
≫ |
| TSC1 |
↻ |
|
|
|
|
|
|
|
≫ |
| SERP1 |
↻ |
|
|
|
|
|
|
|
≫ |
| FGGY |
↻ |
|
|
|
|
|
|
|
≫ |
| EIF2A |
↻ |
|
|
|
|
|
|
|
≫ |
| CTXND1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CLRN1 |
↻ |
|
|
|
|
|
|
|
≫ |
| INTS9 |
↻ |
|
|
|
|
|
|
|
≫ |
| HMBOX1 |
↻ |
|
|
|
|
|
|
|
≫ |
| HARBI1 |
↻ |
|
|
|
|
|
|
|
≫ |
| DGKB |
↻ |
|
|
|
|
|
|
|
≫ |
| ATG13 |
↻ |
|
|
|
|
|
|
|
≫ |
| ARL15 |
↻ |
|
|
|
|
|
|
|
≫ |
| LIPH |
↻ |
|
|
|
|
|
|
|
≫ |
| ZNHIT3 |
↻ |
|
|
|
|
|
|
|
≫ |
| TIAF1 |
↻ |
|
|
|
|
|
|
|
≫ |
| THAP9 |
↻ |
|
|
|
|
|
|
|
≫ |
| SEC31A |
↻ |
|
|
|
|
|
|
|
≫ |
| MED25 |
↻ |
|
|
|
|
|
|
|
≫ |
| LRRC37B |
↻ |
|
|
|
|
|
|
|
≫ |
| FKBP1A |
↻ |
|
|
|
|
|
|
|
≫ |
| ALKBH5 |
↻ |
|
|
|
|
|
|
|
≫ |
| EIF4EBP2 |
↻ |
|
|
|
|
|
|
|
≫ |
| CLCN5 |
↻ |
|
|
|
|
|
|
|
≫ |
| ZNF37A |
↻ |
|
|
|
|
|
|
|
≫ |
| ZBBX |
↻ |
|
|
|
|
|
|
|
≫ |
| TATDN3 |
↻ |
|
|
|
|
|
|
|
≫ |
| NSL1 |
↻ |
|
|
|
|
|
|
|
≫ |
| LAX1 |
↻ |
|
|
|
|
|
|
|
≫ |
| RAB1B |
↻ |
|
|
|
|
|
|
|
≫ |
| PYGB |
↻ |
|
|
|
|
|
|
|
≫ |
| TNFAIP8L2-SCNM1 |
↻ |
|
|
|
|
|
|
|
≫ |
| TNFAIP8L2 |
↻ |
|
|
|
|
|
|
|
≫ |
| SCNM1 |
↻ |
|
|
|
|
|
|
|
≫ |
| MFSD2A |
↻ |
|
|
|
|
|
|
|
≫ |
| MDH1B |
↻ |
|
|
|
|
|
|
|
≫ |
| LYSMD1 |
↻ |
|
|
|
|
|
|
|
≫ |
| FASTKD2 |
↻ |
|
|
|
|
|
|
|
≫ |
| GHR |
↻ |
|
|
|
|
|
|
|
≫ |
| SMTNL2 |
↻ |
|
|
|
|
|
|
|
≫ |
| MAFA |
↻ |
|
|
|
|
|
|
|
≫ |
| GORASP2 |
↻ |
|
|
|
|
|
|
|
≫ |
| BIRC6 |
↻ |
|
|
|
|
|
|
|
≫ |
| ACY3 |
↻ |
|
|
|
|
|
|
|
≫ |
| UQCC2 |
↻ |
|
|
|
|
|
|
|
≫ |
| PTPN3 |
↻ |
|
|
|
|
|
|
|
≫ |
| PSRC1 |
↻ |
|
|
|
|
|
|
|
≫ |
| HSFX3 |
↻ |
|
|
|
|
|
|
|
≫ |
| EOLA1 |
↻ |
|
|
|
|
|
|
|
≫ |
| ZNF329 |
↻ |
|
|
|
|
|
|
|
≫ |
| NBEA |
↻ |
|
|
|
|
|
|
|
≫ |
| MAB21L1 |
↻ |
|
|
|
|
|
|
|
≫ |
| HPCA |
↻ |
|
|
|
|
|
|
|
≫ |
| SFT2D3 |
↻ |
|
|
|
|
|
|
|
≫ |
| MMP24OS |
↻ |
|
|
|
|
|
|
|
≫ |
| MMP24-AS1-EDEM2 |
↻ |
|
|
|
|
|
|
|
≫ |
| HNF4A |
↻ |
|
|
|
|
|
|
|
≫ |
| EIF6 |
↻ |
|
|
|
|
|
|
|
≫ |
| CRTAM |
↻ |
|
|
|
|
|
|
|
≫ |
| FA2H |
↻ |
|
|
|
|
|
|
|
≫ |
| EPHA1 |
↻ |
|
|
|
|
|
|
|
≫ |
| AKR1A1 |
↻ |
|
|
|
|
|
|
|
≫ |
| PYGO2 |
↻ |
|
|
|
|
|
|
|
≫ |
| PBXIP1 |
↻ |
|
|
|
|
|
|
|
≫ |
| LOC101928120 |
↻ |
|
|
|
|
|
|
|
≫ |
| ZNF181 |
↻ |
|
|
|
|
|
|
|
≫ |
| INTS5 |
↻ |
|
|
|
|
|
|
|
≫ |
| GANAB |
↻ |
|
|
|
|
|
|
|
≫ |
| ADGRA1 |
↻ |
|
|
|
|
|
|
|
≫ |
| ACSM2A |
↻ |
|
|
|
|
|
|
|
≫ |
| ZC3H12A |
↻ |
|
|
|
|
|
|
|
≫ |
| LSM14A |
↻ |
|
|
|
|
|
|
|
≫ |
| LIPK |
↻ |
|
|
|
|
|
|
|
≫ |
| ENPP2 |
↻ |
|
|
|
|
|
|
|
≫ |
| BTNL3 |
↻ |
|
|
|
|
|
|
|
≫ |
| TMEM79 |
↻ |
|
|
|
|
|
|
|
≫ |
| TAF1D |
↻ |
|
|
|
|
|
|
|
≫ |
| SMG5 |
↻ |
|
|
|
|
|
|
|
≫ |
| PCSK1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CEBPE |
↻ |
|
|
|
|
|
|
|
≫ |
| C11orf54 |
↻ |
|
|
|
|
|
|
|
≫ |
| TTC7B |
↻ |
|
|
|
|
|
|
|
≫ |
| NR4A2 |
↻ |
|
|
|
|
|
|
|
≫ |
| CRYBG3 |
↻ |
|
|
|
|
|
|
|
≫ |
| SLC43A2 |
↻ |
|
|
|
|
|
|
|
≫ |
| SHANK2 |
↻ |
|
|
|
|
|
|
|
≫ |
| SBNO1 |
↻ |
|
|
|
|
|
|
|
≫ |
| RIOK2 |
↻ |
|
|
|
|
|
|
|
≫ |
| LSM8 |
↻ |
|
|
|
|
|
|
|
≫ |
| DNAH12 |
↻ |
|
|
|
|
|
|
|
≫ |
| CCNG2 |
↻ |
|
|
|
|
|
|
|
≫ |
| WRNIP1 |
↻ |
|
|
|
|
|
|
|
≫ |
| NEUROD1 |
↻ |
|
|
|
|
|
|
|
≫ |
| MYLK4 |
↻ |
|
|
|
|
|
|
|
≫ |
| GBA |
↻ |
|
|
|
|
|
|
|
≫ |
| TMTC2 |
↻ |
|
|
|
|
|
|
|
≫ |
| INAFM2 |
↻ |
|
|
|
|
|
|
|
≫ |
| GLYATL1 |
↻ |
|
|
|
|
|
|
|
≫ |
| TARBP2 |
↻ |
|
|
|
|
|
|
|
≫ |
| SPSB4 |
↻ |
|
|
|
|
|
|
|
≫ |
| SGK2 |
↻ |
|
|
|
|
|
|
|
≫ |
| NPFF |
↻ |
|
|
|
|
|
|
|
≫ |
| MAP3K12 |
↻ |
|
|
|
|
|
|
|
≫ |
| UQCC3 |
↻ |
|
|
|
|
|
|
|
≫ |
| PLEKHA5 |
↻ |
|
|
|
|
|
|
|
≫ |
| LBHD1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CSKMT |
↻ |
|
|
|
|
|
|
|
≫ |
| C11orf98 |
↻ |
|
|
|
|
|
|
|
≫ |
| TNPO1 |
↻ |
|
|
|
|
|
|
|
≫ |
| DDR1 |
↻ |
|
|
|
|
|
|
|
≫ |
| CHGA |
↻ |
|
|
|
|
|
|
|
≫ |
| AMACR |
↻ |
|
|
|
|
|
|
|
≫ |
| FAM47A |
↻ |
|
|
|
|
|
|
|
≫ |
| KNL1 |
↻ |
|
|
|
|
|
|
|
≫ |
| DHRS9 |
↻ |
|
|
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|
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|
|
≫ |
| GAPT |
↻ |
|
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|
≫ |
| HIPK1 |
↻ |
|
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|
≫ |
| HEXIM2 |
↻ |
|
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|
≫ |
| EAPP |
↻ |
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|
≫ |
| DDX18 |
↻ |
|
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|
≫ |
| EXOSC5 |
↻ |
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|
≫ |
| BCKDHA |
↻ |
|
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|
|
|
≫ |
| SNTG2 |
↻ |
|
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|
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|
≫ |
| LY75-CD302 |
↻ |
|
|
|
|
|
|
|
≫ |
| LY75 |
↻ |
|
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|
≫ |
| ANKEF1 |
↻ |
|
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|
≫ |
| TRIQK |
↻ |
|
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|
≫ |
| SF3A3 |
↻ |
|
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|
≫ |
| IER5 |
↻ |
|
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|
≫ |
| FAM222A |
↻ |
|
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|
≫ |
| POLD4 |
↻ |
|
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|
≫ |
| NUDC |
↻ |
|
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|
≫ |
| NR0B2 |
↻ |
|
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|
≫ |
| DSP |
↻ |
|
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|
≫ |
| TARS2 |
↻ |
|
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|
≫ |
| GGTLC2 |
↻ |
|
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|
≫ |
| SART1 |
↻ |
|
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|
≫ |
| NEUROG2 |
↻ |
|
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|
≫ |
| SIX3 |
↻ |
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|
≫ |
| SOX2 |
↻ |
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|
≫ |
| EOMES |
↻ |
|
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|
≫ |
| CCND1 |
↻ |
|
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|
≫ |
| KIF1B |
↻ |
|
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|
≫ |
| CTNND2 |
↻ |
|
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|
≫ |
| SHH |
↻ |
|
|
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|
≫ |
| DKK3 |
↻ |
|
|
|
|
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|
≫ |
| CDH2 |
↻ |
|
|
|
|
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|
≫ |
| ATOH7 |
↻ |
|
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|
≫ |
| GSX2 |
↻ |
|
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|
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|
≫ |
| MAB21L2 |
↻ |
|
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|
≫ |
| POU3F3 |
↻ |
|
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|
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|
≫ |
| PCSK1N |
↻ |
|
|
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|
≫ |
| SOX11 |
↻ |
|
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|
≫ |
| RFPL3 |
↻ |
|
|
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|
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|
≫ |
| FMNL2 |
↻ |
|
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|
≫ |
| FABP7 |
↻ |
|
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|
≫ |
| SIX6 |
↻ |
|
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|
≫ |
| PAX3 |
↻ |
|
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|
≫ |