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<strong>JYE_B</strong>
isww@Ȋw ȊwUVXe@\wj
emailF<a href="mailto:igaki@lif.kyoto-u.ac.jp">_B</a>
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̈Zr[, <strong>6</strong>, e008 (2017)@<a href="http://dx.doi.org/10.7875/leading.author.6.e008">DOI: 10.7875/leading.author.6.e008</a>
Kiichiro Taniguchi & Tatsushi Igaki: <strong>Mechanisms and physiological roles of cell competition.</strong>

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<h2>v </h2>
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<h2>͂߂</h2>
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<h2>1DזEƂ</h2>
@זEicell competitionj́CԂ̈قȂ2ނ̍זEߐڂ󋵂ɂĐ̍זÊ̑ݍpɂNזE̔rƂĒ`ÂDƂ΁CĂgDɂāCKx̍זEƒႢזEƂߐڂƁCKx̒ႢזEsҍזEƂđgDrƂƂɓKx̍זEҍזEƂđBCʓIɔsҍזEҍזEɒuDdvȓ_́CҍזEєsҍזÊPƂł͐ёB\ł邱Ƃłi<a href="#F1">}1</a>jDזE͖쐶^̍זEɂ܂ꂽψٍזEr錻ۂƂĔꂽC̕ψٍזÉgҁhisuper-competitorjƂȂߐڂ쐶^̍זEr邱Ƃoꂽi<a href="#F2">}2</a>jDɂ̂̂C܂܂ȕψقזEЂNƂ炩ɂꂽD

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iajҍזEєsҍזEƂCPƂł͐ёB\łCזE̔rNȂD
ibjҍזEƔsҍזEƂߐڂɂẮCE̕t߂ɂĔsҍזErD
<a href="http://leading.lifesciencedb.jp/wordpress/wp-content/uploads/2017/12/Igaki-6.e008-Fig.1.jpg" target="_blank">[Download]</a></div>[hs_figure id=1&amp;image=/wordpress/wp-content/uploads/2017/12/Igaki-6.e008-Fig.1.png&amp;caption=fig1-caption-text]

<a name="F2"></a><div id="fig2-caption-text" style="display: none;"><strong>}2@זEɂזE̔r</strong>
iaj쐶^̍זE͋ߐڂsҍזErD
ibj҂͋ߐڂ쐶^̍זErD
<a href="http://leading.lifesciencedb.jp/wordpress/wp-content/uploads/2017/12/Igaki-6.e008-Fig.2.jpg" target="_blank">[Download]</a></div>[hs_figure id=2&amp;image=/wordpress/wp-content/uploads/2017/12/Igaki-6.e008-Fig.2.png&amp;caption=fig2-caption-text]


<h2>2DזE̔</h2>
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@̍זE̔30NCזEɂ<em>Minute</em>ψٍזE̔r̎Ԃ쐶^̍זEƂ̋EʂɂA|g[VXł邱Ƃ킩CזEԂ̑ݍpזE̔rIɖ炩ɂꂽ<a href="#R2"><sup>2)</sup></a>D̊ώ@CKẍقȂזEǂߐڂہCKx̍זE͐cCKx̒ႢזE͔rƂזE̊{IȊTOmꂽD

<h2>3DזE̕</h2>
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@<strong><em>Minute</em>/<em>Myc</em>^̍זE</strong>F<em>Minute</em>ψّ̂ɂזE̔30NCVEWEoGɂčזEЂN2̈qoꂽDȂ킿C`qł<em>Myc</em>`qזE͒҂ƂȂCӂ̖쐶^̍זEזEɂr邱Ƃ񍐂ꂽ<a href="#R3"><sup>3,4)</sup></a>D<em>Minute</em>ψق̓^pN̍ቺC<em>Myc</em>`q̍̓^pN̍𘴐i邱ƂC<em>Myc</em>^̍זE<em>Minute</em>^̍זEƓlɃ^pN̍\̑΍ɂN\DۂɁC̍זE̕q@\ɂ͍ʐ݂DזEЂNψق̑<em>Minute</em>ψق邢<em>Myc</em>`qƋ@\Iɑݍp邱ƂC2̍זE͍זE̓Kx𗝉̂ɂƂVvx[XɂȂ郂fłƂD
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@<strong>̂ق̍זE</strong>F_ɂāC<em>Minute</em>/<em>Myc</em>^邢͂}^̂ɂނȂזE݂D̗}oHłHippoVOi`BoHɂ<em>expanded</em>`qC<em>fat</em>`qC<em>salvador</em>`qC<em>hippo</em>`qC<em>warts</em>`qC<em>mats</em>`q̕ψٍזE҂ɂȂ邱Ƃꂽ<a href="#R7"><sup>7)</sup></a>DŁCHippoVOỉɂė}]ʈqYorkie<em>Myc</em>`q̓]ʂU邱Ƃ<a href="#R8"><sup>8)</sup></a>CHippoVOi<em>Myc</em>^̍זEɂ蒴N\lD܂CBVOiłWgVOi̍זEԂł̋x<em>Myc</em>`qɔˑIɍזEЂNƂꂽ<a href="#R9"><sup>9)</sup></a>DWgVOiɂЂNזEɂẮCҍזEɂč镪^pNNotumsҍזẼA|g[VXU<a href="#R9"><sup>9)</sup></a>DɁCBVOiłJAK-STATVOi̍זEԂł̋xזEЂNƂꂽ<a href="#R10"><sup>10)</sup></a>DJAK-STATVOiɂЂNזÉC<em>Minute</em>/<em>Myc</em>^̍זEƓlɁC<em>hid</em>`qɈˑIȔsҍזẼA|g[VXÛ́C̋@\<em>Myc</em>`qWgVOiɂ͔ˑIł邱Ƃꂽ<a href="#R10"><sup>10)</sup></a>DC<em>mahjong</em>`q̕ψٍזEזE̔s҂ƂĂӂ܂Ƃꂽ<a href="#R11"><sup>11)</sup></a>DMahjong͂}^pNƂĂ͂炭ɐ^pNLgl̉̐^pNłC͂C}^pNƂĂ̈ʂDC<em>mahjong</em>ψٍזE͋ɐ̕NC}^̍זEƂ͈قȂ錻ۂłƂ<a href="#R11"><sup>11)</sup></a>DLTCNiG1CSCG2CMjj{TCNiGCSjւƓ]闑hEזEpɂCזEɂ<em>mahjong</em>ψٍזE̔r͕~זEɂĂN邱Ƃꂽ<a href="#R12"><sup>12)</sup></a>D̕~זE̍זÉC<em>Minute</em>ψقɂĂN<a href="#R12"><sup>12)</sup></a>D܂CfɂāCIȍpזEЂN邱ƂC@BIȋimechanical competitionj̊TO񏥂ꂽ<a href="#R13"><sup>13)</sup></a>DVEWEoG̔w̔fɂɂCזEߖƂɑB̍ɂ萶@BIȎhᑝB̍זEɃA|g[VXUƂ@BIȋ̎Ⴊꂽ<a href="#R14"><sup>14)</sup></a>D

<h2>4D<em>Minute</em>/<em>Myc</em>^̍זE̐@\</h2>
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ibjÐHfDҍזEsҍזEÐHD
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@<em>Myc</em>^̍זE̐@\ɂẮgFlower-Azot䃂fhсgRƉuVOi䃂fh񏥂ĂD2̃fƂC<em>Myc</em>^̍זE̐@\<em>Minute</em>^̍זEɂKp\ł邱ƂCҍזEƔsҍזEƂ̒ړIȐڐGזE̔rɕKvǂƂ_2̃f͈قȂD܂Cۂ̍זEɂāCꂼ̐@\ǂ̂炢^邩ɂẮC݁CmȃRZTX͓ĂȂD
@<strong>Flower-Azot䃂f</strong>F<em>Myc</em>`q̍ɂ蒴ЂNVEWEoGɂĈ`q̃vt@C͂邱ƂɂC<em>flower</em>`qC<em>SPARC</em>`qC<em>azot</em>`qƂזE𐧌䂷3̈`q肳ꂽ<a href="#R16"><sup>16-18)</sup></a>DÄ`wIȉ͂ɂC<em>Myc</em>`qזEƖ쐶^̍זEƂ̒ړIȐڐGɂC쐶^̍זEɂFlower-AzotVOi`BoHƂf񏥂ꂽi<a href="#F4">}4a</a>jDђʃ^pNR[h<em>flower</em>`q͑IIXvCVOɂ3ނ̃AC\tH[YD̂ЂƂ͏ҍזECc2͔sҍזEɂĎYꂽƂCFlower͏ҍזEƔsҍזEW^pNłƍlꂽ<a href="#R17"><sup>17)</sup></a>DsҍזE^FlowerYזÉCҍזE^FlowerYזEƂ̒ړIȐڐG<em>azot</em>`q̔UDAzot̓A|g[VXU`qł<em>hid</em>`q̔U邱ƂɂsҍזE̔rЂN<a href="#R16"><sup>16)</sup></a>DCsҍזEɂĂ͊ꖌ\镪^pNSPARC̔U<a href="#R18"><sup>18)</sup></a>DSPARĆCAzotɂA|g[VX̗Uɑ΂}Iɂ͂炭ƂɂCꎞIɓKxቺ̍זEsKvɔr̂}ƂDFlower-AzotVOi`BoHɂ鏟ҍזEƔsҍזE̕WэזE̗ÚC<em>Minute</em>^̍זEɂĂlɋ@\邱ƂꂽD

<a name="F4"></a><div id="fig4-caption-text" style="display: none;"><strong>}4@<em>Minute</em>/<em>Myc</em>^̍זEɂ鐧@\</strong>
iajFlower-Azot䃂fD
ibjRƉuVOi䃂fD
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@<strong>RƉuVOi䃂f</strong>FҍזE͂Ȃđ݂sҍזEɂĂA|g[VXN_ɒڂCזE̐ɂtq̏dv񏥂ꂽ<a href="#R19"><sup>19)</sup></a>D̂̂CTCgJCSpatzleToll֘AéiToll-related receptorFTRRjɂ鎩RƉuVOiĔsҍזErƂVȃf񏥂ꂽ<a href="#R20"><sup>20)</sup></a>i<a href="#F4">}4b</a>jD<em>Myc</em>`q̍ɂ钴ɂ鎩RƉuVOi̊֗^ׂCOA׋ۂɑ΂鉞oHłImdVOi`BoH̍\^pNłPGRP-LCCFADDCEct4CDreddCCasperCRelish̍זEɕKvł邱ƂꂽDsҍזEɂȂ쐶^̍זEɂāCTCgJCSpatzleTRR2CTRR3CTRR8CTRR9ƌẴVOi`BoHCɂ]ʈqRelish<em>hid</em>`q̓]ʂUA|g[VXND<em>Minute</em>^̍זEɂẮCsҍזEɂȂ<em>Minute</em>ψٍזEɂTRR3TRR9Đ^ۂɑ΂鉞oHłTollVOi`BoHC̉̍\^pNłCactusCdlCDifăA|g[VXU^pNReaper̔UA|g[VXNDsҍזEɂTRR2CTRR8CTRR9̔U邱ƂCꂪזẼgK[ɂȂ\lD

<h2>5D}^̍זE̐@\</h2>
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ibjɐ̕󂵂זEɂāCJNKVOiEGFẽVOi̋ɂ肪񉻂D
<a href="http://leading.lifesciencedb.jp/wordpress/wp-content/uploads/2017/12/Igaki-6.e008-Fig.5.jpg" target="_blank">[Download]</a></div>[hs_figure id=5&amp;image=/wordpress/wp-content/uploads/2017/12/Igaki-6.e008-Fig.5.png&amp;caption=fig5-caption-text]

@<strong>sҍזE̕IȔr</strong>Fɐ̕󂵂זÊӂ܂̂ЂƂƂāCw̒[邢͊ꑤւ̗EmĂDVEWEoG̈`wIȃXN[jOɂC<em>scrib</em>ψٍזEɂJNKVOi̓A|g[VX̗Û݂Ȃ炸sҍזE̕IȔrɂ֗^邱Ƃꂽ<a href="#R21"><sup>21)</sup></a>i<a href="#F5">}5a</a>jDȂ킿CJNKVOi͐_o̓˂̐Ɋ֗^SlitCRobo2CEnabled̔UCɂ<em>scrib</em>ψٍזEɂSlit-Robo2VOiẲ̕WIłEnabledDEnabled̓AN`^pN̂ЂƂłCAhwXWNV\EJhw̕זẺ^̑iɂ<em>scrib</em>ψٍזȄw̕IȔr𑣐iDRobo2-EnabledVOi`BoHJNKVOi邱ƂmFCזE̔rɂÃVOi͐̃tB[hobN`ƍlD
@<strong>sҍזȆB̗}эזE̗U</strong>Fɐ̕ɂЂNזEɂẮCҍזEƔsҍזEƂ̔F2̍זE\ʂ̖^pNSasPtp10Dɂ萧䂳邱Ƃꂽ<a href="#R23"><sup>23)</sup></a>i<a href="#F5">}5a</a>jDSasPtp10D́CSlitCRobo2CEnabledƓlɐ_o̓˂̐Ɋ֗^CSasKhƂāCPtp10DêƂċ@\DSasPtp10D͏זEł͂ƂɍזE̒[ɋǍ݂CאڂזEɂނʂɒ񎦂邱Ƃ͂ȂDCgDɂċɐ󂵂<em>scrib</em>ψٍזEoƁC<em>scrib</em>ψٍזEƖ쐶^̍זEƂ̋EʂɂāC쐶^̍זESasC<em>scrib</em>ψٍזEPtp10DזȆʂɒ񎦂CsҍזEɂSas-Ptp10DVOigXɊDSas-Ptp10DVOiɂ鑝B̗}𗝉ɂ́Cɐ̕󂵂זEɂ邪̌`@\𗝉Kvi<a href="#F5">}5b</a>jDזEɂɐ́̕CJNKVOiɂ킦EGFẽVOi̊ЂNDJNKVOiEGFẽVOi͋Iɋ@\邱ƂɂJubDJub̊̓AN`̍ĕҐHippoVOi}CʂƂāCזẺߏȑB邢͂񉻂ЂN<a href="#R25"><sup>25)</sup></a>DŁCSas-Ptp10DVOȋ݉ł́CSasɂɐ̕󂵂זEɂĊPtp10DEGFê炭ړIɒE_邱Ƃɂ肻̃VOi}DɂCJNKVOiA|g[VX̗UVOiƂċ@\悤ɂȂDɁCJNKVOiHippoVOiɑ΂iIɂ͂炭ƂɂזȆB}DSas-Ptp10DVOíC<em>Minute</em>ψفC<em>Myc</em>`q̍CHippoVOi̒ቺɂזEɂ͊֗^ȂƂC<em>Minute</em>/<em>Myc</em>^̍זEƂ}^̍זEł͐@\傫قȂƍlD

<h2>6DMނɂזE</h2>
@VEWEoGɂČoꂽזEƓl̋IȍזE̔rMނ̃fɂĂώ@悤ɂȂCזELۑꂽזEԂ̃R~jP[Vłƍl悤ɂȂD
@Ck̏琫̔|{זEłMDCKזEpāC`qł<em>Ras</em>`q邢<em>Src</em>`qזEȍזEɂ܂ƁCPw|{r邱Ƃoꂽ<a href="#R26"><sup>26,27)</sup></a>D̂ƂCҍזEɂȂ쐶^̍זEɂẮCAN`^pNFilamin<em>Ras</em>`q邢<em>Src</em>`qזEƂ̋EʂɏWςCVimentin̑𑣐i邱ƂɂזE̔rЂN<a href="#R28"><sup>28)</sup></a>DŁCsҍזEɂȂ<em>Ras</em>`q邢<em>Src</em>`qזEɂẮCAN`^pNłEPLINW邱ƂɂII^~IVveCLi[[ACgD̗Ei<a href="#R29"><sup>29)</sup></a>DEPLINPDK4ă~gRhȀQщ𓜌n̘iЂN<a href="#R30"><sup>30)</sup></a>i<a href="http://first.lifesciencedb.jp/archives/16452" target="_blank">V_r[</a> łfځjDPDK4ɂ~gRhȀQsҍזE̔rɕKvłƂCזEɂӂזEɂďdvȋ@\\ꂽD
@̑̎̃fł<em>DPPIV</em>ψك}EX̊̑ɖ쐶^َ̑e̊̊זEڐAƁCڐAזȆBыߐڂ<em>DPPIV</em>ψٍזẼA|g[VXɂ͖̑쐶^̍זEɒuĂƂoCזEgD̍č\z̉\ꂽ<a href="#R31"><sup>31)</sup></a>D܂C}EX̔畆gDɂѕɒڂC񌴐̕ψٍזE쐶^̍זEr邱Ƃoꂽ<a href="#R32"><sup>32)</sup></a>Dѕ͐ƑލsԂƂIȑӃVXeCψٍזE͑ލsɂđgD珜D̍זE̔r͎ӂ̖쐶^̍זȆ݂ɈˑċN邱ƂCזEł\D
@<em>Minute</em>/<em>Myc</em>^̍זE͚Mނ̌̂ɂĂoꂽDL}EXpnɂāCVEWEoGƓlɃ{\[^pN`q̕ψٍזẺߒɂčזEɂ̂r邱Ƃꂽ<a href="#R33"><sup>33)</sup></a>D܂C}EX̏̃GsuXg<em>Myc</em>^̍זEɂIʂ邱Ƃꂽ<a href="#R34"><sup>34,35)</sup></a>D}EXɂזEÐH֗^邱ƂCVEWEoGɂזEƂ̗ގDC<em>scrib</em>ψقɂזEMނ̍זEɂČoꂽD<em>scrib</em>`qmbN_EMDCKזEMDCKזEɂ܂ƔsҍזEƂȂr邱Ƃꂽ<a href="#R36"><sup>36)</sup></a>D<em>scrib</em>ψقɂЂNMDCKזE̔ŕCJNKł͂Ȃp38 MAPKċNDʂ̌O[v́C<em>scrib</em>ψٍזȄ@BIȋłƂĂ<a href="#R37"><sup>37)</sup></a>D̂悤ɁCזEɂזE̔r̋@\̓VEWEoGƚMނƂŕKʂĂȂDŁC<em>mahjong</em>`qmbN_EMDCKזEɂẮCVEWEoGƓl̋@\ŃA|g[VXɂr邱Ƃꂽ<a href="#R11"><sup>11)</sup></a>D
@HippoVOi`BoHזEMނ̃fɂĕ񍐂ꂽD}EX̔|{זEłNIH3T3זEpāCHippoVOi`BoHꂽ<a href="#R38"><sup>38)</sup></a>DMނɂHippoVOỉɂė}YaṕC]ʈqTeadƌĕWIɂȂ`q̓]ʂUDTead̊x̑΍NIH3T3זE̍זEЂNCTead̊ƏҍזECTead̊ႢƔsҍזEɂȂ邱ƂꂽD܂CTead<em>Myc</em>`q̔U邱ƂCMނɂHippo-MycVOi`BoH݂̑ꂽDŁCʂ̌O[vɂCMDCKזEɂĂYap̊זEזEɂĔsҍזEɂȂ邱Ƃꂽ<a href="#R39"><sup>39)</sup></a>DזEƏזEƂłHippoVOi`BoHɕψقזÊӂ܂قȂ̂ȂD

<h2>7DזE̐IȈӋ`</h2>
@זEɂזȄWc̕iǗ́CƎȍזEaςזȆgD̔r\ɂƍlDCזEۂɐ̃VXëێɂċ@\邱Ƃ𒼐ړIɎ񍐂͏ȂD́C܂ōזE̋@\̂͂邱ƂłƂlΓR̂ƂȂDȂCזE쓮זEԂ̃R~jP[Vɂ͂炭^pN肳ꂽƂɂC̐IȈӋ`̉͂\ɂȂĂDזE̐Iȋ@\ƂāC̗}CQזE̔rC̂ɂ锭̐ɂĉD
@<strong>̗}</strong>F<em>Minute</em>/<em>Myc</em>^̍זEт}^̍זEƂC̐Ƃ̖ڂȊ֌W\zDŁCۂɍזE̔邢͐iWɊ^Ƃ؋͂܂قƂǂȂD̂ȂłCqĝgDɂčRSPARCR̂pĔsҍזEW邱ƂɂזE̗LׂCۂɁCXǑBƔrĖ쐶^̍זESPARC邱Ƃꂽ<a href="#R40"><sup>40)</sup></a>D̕aςɂSPARC̔̕ϓɂĂ͉ߋɂ̕񍐂C̐iWƍזEƂ̊֌WD܂C}EXɂ<em>flower</em>`q̃zOł<em>mflower</em>`q}EX쐻CU̔畆ps[}̑B}邱Ƃꂽ<a href="#R41"><sup>41)</sup></a>ĎʂCזE҂ɂȂ邱ƂőgDɂĊg傷\ꂽDCqgɂPtp10D̃zOłPTPRJ͂}^pNƂċ@\邱ƂmĂ<a href="#R42"><sup>42)</sup></a>DPTPRJ̓VEWEoGPtp10DƓlEGFêɑ΂}\Ƃ킩ĂCqĝɂĂVEWEoGƓl̍זE̗}̋N\DCSPARCCmFlowerCPTPRJɂ邪̐䂪זE̂ł邩ǂɂĂ͂܂\ɒׂĂȂDMނ̃fɂ邪ƍזE̊֌WɂẮCȂ͂KvłD
@<strong>QזE̔r</strong>FזE̐񂪂݂΁CזEɂזȄWc̕iǗgĎ퐫̈ێɍv\͍DCזEƑgDɂP퐫Ƃ̈ʊ֌WɂĎ񍐂͂܂ȂDAzot̉͂āCזEQזE̔rɊ֗^邱Ƃ񏥂ꂽ<a href="#R16"><sup>16)</sup></a>DVEWEoG͗čɌɐ邪C̎ɎȌƎ˂ɂזEQXgXĂ̌`Ɉُ͐ȂDC<em>azot</em>ψّ͎̂ȌƎ˂ɂ茰ȈُĎʂČ`Ɉُ𐶂悤ȏQזE͓ݐ̍זEɂr邱ƂDۂɁC<em>azot</em>ψّ̂ɂُ̈́C<em>azot</em>`q̃GnT[ɈˑăA|g[VXU邱Ƃɂ背XL[D܂CAzotɂA|g[VX̗U̂̎L΂ƂCgD̍P퐫̈ێɂזȄdv񎦂ꂽD
@<strong>̂ɂ锭̐</strong>F̂̔̉ߒɂčזE̐𐧌䂷iƂāCזEߏɎŶsvȍזE菜Ƃ͂߂炵͂ȂDזE͂̂悤ȉߒɂĕsvȍזȄDǂȍזȆIɊ֗^\ꂽDFlower-AzotVOi`BoHזEVEWEoGɂ镡̔̉ߒɂĐsvȎ_o邱Ƃ񍐂ꂽ<a href="#R16"><sup>16,43)</sup></a>DȑOČ`̉ߒɂĂ͕Ӊ̃j[A|g[VXNƂmĂC̍זE̔r͔sҍזE^FlowerɂsvȍזEsҍזEƂĕW邱ƂɂN邱ƂꂽDC<em>Myc</em>^̍זE}EX̏̔ɂėDǂȃGsuXg̑IʂɊ^邱Ƃ񍐂ꂽ<a href="#R34"><sup>34,35)</sup></a>D󔭐̏̊זEv[ɂčזEɂDǂȍזEIʂƂ̕񍐂́C炾Â̍{ɍזE݂邱ƂC傫ȃCpNgD

<h2></h2>
@זE̔40NC悤₭̌ۂ̕qԂ̗iłDFlower-AzotVOi`BoHSas-Ptp10DVOiɂ鏟ҍזEƔsҍזẼR~jP[V̋@\݂ĂƂɂCזEǂoH݂̑mȂ̂ɂȂDŁC<em>Minute</em>/<em>Myc</em>^̍זE̐@\ɂẮC܂RZTXɂĂȂDזE쓮זE̓Kx̌@\эזE̔r̋@\𗝉邤ŁC<em>Minute</em>/<em>Myc</em>^̍זȆSẻ𖾂͕K{łDC}^̍זE̐ɂ^pNƂāC_o̓˂̐Ɋ֗^^pN肳ꂽƂ͋[D_o̓˂̐́CقȂזE̔FƂɉזE̋\ɂ邷ꂽnłCזE̐Ƃʂ_DŁCׂĂ̍זEFlower-AzotVOi`BoH邢Sas-Ptp10DVOiɂ킯ł͂ȂC̑Se͈ˑRƂđ̓ɂ܂ĂDߔNC܂܂ȃ^Cv̍זEoꂽƂɂCזẼgK[ɂȂq␧@\͑lł邱Ƃ킩ĂDŁC瑽lȍזE͂ގזE̋̂́C͂܂قȂ鐶݂̉Ă\DClȍזEɒʒꂷ{oƂɂC^̈ӖōזE悤ɂȂƎvD
@VEWEoGɂČoꂽ<em>Minute</em>/<em>Myc</em>^̍זEт}^̍זEMނɂ݂C̐@\ɂގ_Ƃ͏dvłDCזĚ瓾ꂽmC͂߂Ƃ܂܂Ȏ̗₻̎Ö@̊Jɉp邱Ƃ\ɂȂ邩ȂD܂CזE͕sǂȍזEDǂȍזEɒu邱Ƃ\ȃVXełC̉pɂĐÂ⍜ڐAȂǂ܂܂ȈÂւ̍v҂DCזE̐IȈӋ`̉𖾂ɂCזEԂ̃R~jP[V̂̔邢͐̂̈ێ̋@\̍{IȗCɂ́CזEȂR~jeB錴ɂ܂邱Ƃł邩ȂDזE̂ɂ锭̃CxgɊ֗^Ƃ͏dvȈӖDȂ킿C̂̔͒PɔvOɂAIȈ`q݂̂Ő̂ł͂ȂCזEIm_IȍזEԂ̑ݍpэזE^̐v邱ƂD

<h2> </h2>
<ol>
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<li id="R18"><span class='au'>Portela, M., Casas-Tinto, S., Rhiner, C. et al.</span>: <span class="ti"><em>Drosophila</em> SPARC is a self-protective signal expressed by loser cells during cell competition.</span> <span class='so'>Dev. Cell, 19, 562-573 (2010)[<a href="http://www.ncbi.nlm.nih.gov/pubmed/20951347" target="_blank">PubMed</a>]</span></li>
<li id="R19"><span class='au'>Senoo-Matsuda, N. & Johnston, L. A.</span>: <span class="ti">Soluble factors mediate competitive and cooperative interactions between cells expressing different levels of <em>Drosophila</em> Myc.</span> <span class='so'>Proc. Natl. Acad. Sci. USA, 104, 18543-18548 (2007)[<a href="http://www.ncbi.nlm.nih.gov/pubmed/18000039" target="_blank">PubMed</a>]</span></li>
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</ol>
<div class="au-profile">
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<span class="author">J YiKiichiro Taniguchij</span>
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