The database of an integrated information resource of diseases, drugs, and health-related substances, aiming to bring the genomic revolution to society.
Data name | README |
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Description of data contents | HTML file to describe "KEGG MEDICUS" data. |
File | README_e.html (English) |
Data name | Drug |
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Description of data contents | KEGG DRUG is a comprehensive drug information resource for approved drugs in Japan, USA, and Europe unified based on the chemical structures and/or the chemical components, and associated with target, metabolizing enzyme, and other molecular interaction network information. |
File | kegg_medicus_drug_en.zip (1.1 MB) |
Data item | Description |
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D number | Unique identifier of the KEGG DRUG entry. |
Classification | Shown when the drug is Mixture, Crude or Formula. |
Name | The generic name and selected trade names of the drug. |
Component | |
Formula | The molecular formula of the drug structure. |
Exact mass | The exact mass of the drug structure. |
Mol weight | The molecular weight of the drug structure. |
Structural formula | Chemical structural formula. (Simple search only) |
Sequence | Sequence data when the drug is a peptide or a polyketide. |
Sequence type | Sequence type (NRP, PK, Peptide). |
Source | Biological source when the drug is derived from a natural product. |
Upper DGroup | Upper DGroup. |
Remark | This field contains Therapeutic category, ATC code, and also identical entries in the COMPOUND database. |
Activity | Efficacy and activity of the drug. |
Disease | The desease healed by the drug. |
Comment | Free text comment. |
Target | Target information of the drug with appropriate links to human genes and KEGG Orthology. |
Metabolism | Information about drug metabolizing enzyme and transporter. |
Interaction | Other interaction information, including CYP induction and inhibition, genomic biomarkers, etc. |
Other DBs | Links to outside databases. |
KCF data | The KCF (KEGG Chemical Function) representation of the chemical structure can be displayed here. It contains the KEGG atom type information for use in chemical structure comparisons. |
Data name | Environ |
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Description of data contents | KEGG ENVIRON is a collection of crude drugs, essential oils, and other health-promoting substances, which are mostly natural products. KEGG ENVIRON supplements KEGG DRUG that contains officially approved drugs. |
File | kegg_medicus_environ_en.zip (74 KB) |
Data item | Description |
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E number | Unique identifier of the KEGG ENVIRON entry. |
Name | Name of the natural product. |
Category | Category (Crude drug, Essential oil or Medicinal herb). |
Component | Chemical components and corresponding C/D numbers. |
Source | Biological source with links to NCBI taxonomy IDs. |
Remark | D number of the same crude drug, etc. when available. |
Comment | Free text comment. |
Other DBs | Links to outside databases. |
Data name | Disease |
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Description of data contents | The KEGG DISEASE database is a collection of human diseases, each represented as a list of disease genes, environmental factors, pathogens, etc. with links to corresponding KEGG objects, thus enabling computational processing and analysis of disease data. |
File | kegg_medicus_disease_en.zip (1.4 MB) |
Data item | Description |
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H number | Unique identifier of the KEGG DISEASE entry. |
Name | Disease names including alternative names. |
Description | A brief summary of the disease. |
Category | The category of the disease. |
Gene | Known disease genes with links to the KEGG GENES and KO databases. |
Pathogen | Known pathogens with links to the KEGG GENOME and VGENOME databases. |
Env factor | Known other environmental factors with links to the KEGG COMPOUND and other databases. |
Carcinogen | Known carcinogens with links to the KEGG COMPOUND and other databases. |
Marker | Typical diagnostic markers with links to the KEGG GENES and COMPOUND databases. |
Drug | Typical therapeutic drugs with links to the KEGG DRUG database. |
Comment | Free text comment. |
Other DBs | Links to outside databases. |
Reference | Reference information. |
Data name | DGroup |
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Description of data contents | KEGG DGROUP is a new database under development for structurally and functionally related groups of drugs, especially from the viewpoint of drug interaction networks. |
File | kegg_medicus_dgroup_en.zip (269 KB) |
Data item | Description |
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DG number | Unique identifier of the KEGG DGROUP entry. |
Classification | Shown when the group is "Chemical". |
Name | Name of the DGroup. |
Stem | Stem of drugs in the DGroup. |
Structural formula | Chemical structural formula. (Simple search only) |
Member | List of drugs and D numbers in the DGroup. |
Upper DGroup | Upper DGroup. |
Remark | ATC code. |
Comment | Free text comment. |
Target | Target information of the drug with appropriate links to human genes and KEGG Orthology. |
Metabolism | Information about drug metabolizing enzyme and transporter. |
Interaction | Other interaction information, including CYP induction and inhibition, genomic biomarkers, etc. |
You may use this database in compliance with the terms and conditions of the license described below. The license specifies the license terms regarding the use of this database and the requirements you must follow in using this database.
The license for this database is specified in the Creative Commons Attribution-Share Alike 4.0 International.
If you use data from this database, please be sure attribute this database as follows: "KEGG MEDICUS © Minoru Kanehisa (Kyoto Univ.) licensed under CC Attribution-Share Alike 4.0 International".
The summary of the Creative Commons Attribution-Share Alike 4.0 International is found here.
With regard to this database, you are licensed to:
under the license, as long as you comply with the following conditions:
Institute for Chemical Research, Kyoto University
Uji, Kyoto 611-0011, Japan
TEL: +81-774-38-4521
http://www.genome.jp/feedback/
You can freely provide links to all contents in this database. But, contents might be changed without notice.
Date | Update contents |
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2017/12/15 | Archive V2 is released. |
2014/05/09 | KEGG MEDICUS English archive site is opened.(Archive V1) |
2010/10/01 | KEGG MEDICUS (http://www.kegg.jp/kegg/medicus/) is opened. |
Institute for Chemical Research, Kyoto University
Uji, Kyoto 611-0011, Japan
TEL: +81-774-38-4521
http://www.genome.jp/feedback/