GM12878 Homo sapiens 1 B-lymphocyte, lymphoblastoid, International HapMap Project - CEPH/Utah - European Caucasion, Epstein-Barr Virus mesoderm blood normal F ENCODE Coriell GM12878 BTO:0002062 GM12878 H1-hESC Homo sapiens 1 embryonic stem cells inner cell mass embryonic stem cell normal M ENCODE WiCell Research Institute WA01 CL:0000007 H1-hESC K562 Homo sapiens 1 leukemia, "The continuous cell line K-562 was established by Lozzio and Lozzio from the pleural effusion of a 53-year-old female with chronic myelogenous leukemia in terminal blast crises." - ATCC mesoderm blood cancer F ENCODE ATCC CCL-243 BTO:0000664 K562 A549 Homo sapiens 2 epithelial cell line derived from a lung carcinoma tissue. (PMID: 175022), "This line was initiated in 1972 by D.J. Giard, et al. through explant culture of lung carcinomatous tissue from a 58-year-old caucasian male." - ATCC, newly promoted to tier 2: not in 2011 analysis endoderm epithelium cancer M Myers ATCC CCL-185 BTO:0000018 A549 CD20+ Homo sapiens 2 B cells from donors RO01778 and RO01794, newly promoted to tier 2: not in 2011 analysis mesoderm blood normal F Stam Dr. Heimfeld Lab at FHCRC CD20+ BTO:0000776 B-cells CD20+ CD20+ RO01778 Homo sapiens 2 B cells, caucasian, draw number 1, newly promoted to tier 2: not in 2011 analysis mesoderm blood normal F Stam Rajinder Kaul, UW CD20+_RO01778 BTO:0000776 B-cells CD20+ (RO01778) CD20+ RO01794 Homo sapiens 2 B cells, African American, draw number 1, newly promoted to tier 2: not in 2011 analysis mesoderm blood normal F Stam Rajinder Kaul, UW CD20+_RO01794 BTO:0000776 B cells CD20+ RO01794 H1-neurons Homo sapiens 2 neurons derived from H1 embryonic stem cells, newly promoted to tier 2: not in 2011 analysis ectoderm neurons normal M Cellular Dynamics International Batch 1 CDI TBD BTO:0000938 H1-neurons HeLa-S3 Homo sapiens 2 cervical carcinoma ectoderm cervix cancer F ENCODE ATCC CCL-2.2 BTO:0000568 HeLa-S3 HepG2 Homo sapiens 2 hepatocellular carcinoma endoderm liver cancer M ENCODE ATCC HB-8065 BTO:0000599 HepG2 HUVEC Homo sapiens 2 umbilical vein endothelial cells mesoderm blood vessel normal U ENCODE Lonza CC-2517 BTO:0001949 HUVEC IMR90 Homo sapiens 2 fetal lung fibroblasts, newly promoted to tier 2: not in 2011 analysis endoderm lung normal F Stam ATCC CCL-186 BTO:0001229 IMR90 LHCN-M2 Homo sapiens 2 skeletal myoblasts derived from satellite cells from the pectoralis major muscle of a 41 year old caucasian heart transplant donor, immortalized with lox-hygro-hTERT ("LH"), and Cdk4-neo ("CN"), Zhu et al. (2007) in Aging Cell, vol. 6, pp 515-523, newly promoted to tier 2: not in 2011 analysis. mesoderm skeletal muscle myoblast M Wold Dr. Woodring Wright Missing BTO:0005046 LHCN-M2 MCF-7 Homo sapiens 2 mammary gland, adenocarcinoma. (PMID: 4357757), newly promoted to tier 2: not in 2011 analysis ectoderm breast cancer F Crawford ATCC HTB-22 BTO:0000093 MCF-7 Monocytes-CD14+ Homo sapiens 2 Monocytes-CD14+ are CD14-positive cells from human leukapheresis production, from donor RO 01746 (draw 1 ID is RO 01746, draw 2 ID is RO 01826), newly promoted to tier 2: not in 2011 analysis mesoderm monocytes normal F Stam S. Heimfeld Laboratory, FHCRC Monocytes-CD14+ BTO:0000876 Monocytes CD14+ Monocytes-CD14+ RO01746 Homo sapiens 2 Monocytes-CD14+ are CD14-positive cells from human leukapheresis production, from donor RO 01746 (draw 1 ID is RO 01746, draw 2 ID is RO 01826), Monocytes-CD14+_RO01746 and Monocytes-CD14+_RO01826 are being used as replicates, newly promoted to tier 2: not in 2011 analysis mesoderm monocytes normal F Stam S. Heimfeld Laboratory, FHCRC Monocytes-CD14+_RO01746 BTO:0000876 Monocytes CD14+ RO01746 Monocytes-CD14+ RO01826 Homo sapiens 2 Monocytes-CD14+ are CD14-positive cells from human leukapheresis production, Monocytes-CD14+_RO01826 is a second draw being used as a replicate for Monocytes-CD14+_RO01746, newly promoted to tier 2: not in 2011 analysis mesoderm monocytes normal F Stam S. Heimfeld Laboratory, FHCRC Monocytes-CD14+_RO01826 BTO:0000876 Monocytes CD14+ RO01826 SK-N-SH Homo sapiens 2 neuroblastoma, newly promoted to tier 2: not in 2011 analysis, the SK-N-SH line was established from a neuroblastoma in a 4 year old individual. ectoderm brain cancer F Myers ATCC HTB-11 BTO:0001620 SK-N-SH 8988T Homo sapiens 3 pancreas adenocarcinoma (PA-TU-8988T), "established in 1985 from the liver metastasis of a primary pancreatic adenocarcinoma from a 64-year-old woman" - DSMZ endoderm liver cancer F Crawford DSMZ ACC 162 BTO:0001521 (non-specific) 8988T Adult CD4 naive Homo sapiens 3 CD4+ cells isolated from human blood and enriched for naive populations mesoderm blood normal B Crawford Stam Dr. David Randolph at University of Alabama, Birmingham Adult_CD4_naive BTO:0000782 T cells CD4+ naive adult Adult CD4 Th0 Homo sapiens 3 CD4+ cells isolated from human blood and enriched for Th0 populations mesoderm blood normal B Crawford Dr. David Randolph at University of Alabama, Birmingham Adult_CD4_Th0 BTO:0000782 T cells CD4+ Th0 adult Adult CD4 Th1 Homo sapiens 3 CD4+ cells isolated from human blood and enriched for Th1 populations mesoderm blood normal B Crawford Stam Dr. David Randolph at University of Alabama, Birmingham Adult_CD4_Th1 BTO:0000782 T cells CD4+ Th1 adult AG04449 Homo sapiens 3 fetal buttock/thigh fibroblast skin normal M Stam Coriell AG04449 BTO:0001253 AG04449 AG04450 Homo sapiens 3 fetal lung fibroblast endoderm lung normal M Stam Coriell AG04450 BTO:0000763 AG04450 AG09309 Homo sapiens 3 adult toe fibroblast from apparently healthy 21 year old, "7% of the cells examined showing random chromosome loss/gain" -Coriell skin F Stam Coriell AG09309 BTO:0001253 AG09309 AG09319 Homo sapiens 3 gum tissue fibroblasts from apparently heathly 24 year old gingival normal F Stam Coriell AG09319 BTO:0004138 AG09319 AG10803 Homo sapiens 3 abdominal skin fibroblasts from apparently heathly 22 year old, "8% of the cells examined showing random chromosome loss, 2% showing random chromosome gain, and 2% showing 69,XYY" -Coriell skin M Stam Coriell AG10803 BTO:0001253 AG10803 AoAF Homo sapiens 3 aortic adventitial fibroblast cells mesoderm blood vessel normal F Stam Lonza CC-7014, CC-7014T75 BTO:0000135 AoAF AoSMC Homo sapiens 3 aortic smooth muscle cells mesoderm blood vessel normal U Crawford Lonza CC-2571 BTO:0001685 AoSMC BC Adipose UHN00001 Homo sapiens 3 adipose tissue, donor UHN0001, age 35, African American, DNA extract adipose tissue normal F Myers BioChain D4234003_A701166 BTO:0001487 Adipose BC UHN00001 BC Adrenal Gland H12803N Homo sapiens 3 adrenal gland, donor H12803N, age 88, caucasian, DNA extract ectoderm, mesoderm adrenal gland normal F Myers BioChain D1234004_B103117 BTO:0000047 Adrenal Gland BC H12803N BC Bladder 01-11002 Homo sapiens 3 urinary bladder, donor 01-11002, age 83, caucasian, DNA extract endoderm urinary bladder normal F Myers BioChain CP-S12-D1234010-05_B402059 BTO:0001418 Bladder BC 01-11002 BC Brain H11058N Homo sapiens 3 brain, donor H11058N, age 66, Asian, DNA extract ectoderm brain normal M Myers BioChain D4234035_A810101 BTO:0000142 Brain BC H11058N BC Breast 02-03015 Homo sapiens 3 breast, donor 02-03015, age 21, caucasian, DNA extract ectoderm breast normal F Myers BioChain D4234086_A710031 BTO:0000149 Breast BC 02-03015 BC Colon 01-11002 Homo sapiens 3 colon, donor 01-11002, age 83, caucasian, DNA and RNA extract endoderm colon normal F Myers BioChain CP-S12-D1234090-05_A903056 BTO:0000269 Colon BC 01-11002 BC Colon H12817N Homo sapiens 3 colon, donor H12817N, age 71, caucasian, DNA and RNA extract endoderm colon normal M Myers BioChain CP-S13-D1234090-05_B111123 BTO:0000269 Colon BC H12817N BC Esophagus 01-11002 Homo sapiens 3 esophagus, donor 01-11002, age 83, caucasian, DNA and RNA extract endoderm esophagus normal F Myers BioChain CP-S12-D1234106-05_A803198 BTO:0000959 Esophagus BC 01-11002 BC Esophagus H12817N Homo sapiens 3 esophagus, donor H12817N, age 71, caucasian, DNA extract endoderm esophagus normal M Myers BioChain CP-S13-D1234106-05_B302113 BTO:0000959 Esophagus BC H12817N BC Jejunum H12817N Homo sapiens 3 jejunum, donor H12817N, age 71, caucasian, DNA and RNA extract endoderm jejunum normal M Myers BioChain CP-S13-D1234230-05_B402068 BTO:0000657 Jejunum BC H12817N BC Kidney 01-11002 Homo sapiens 3 kidney, donor 01-11002, age 83, caucasian, DNA and RNA extract mesoderm kidney normal F Myers BioChain CP-S12-D1234142-05_B402060 BTO:0000671 Kidney BC 01-11002 BC Kidney H12817N Homo sapiens 3 kidney, donor H12817N, age 71, caucasian, DNA and RNA extract mesoderm kidney normal M Myers BioChain CP-S13-D1234142-05_B402061 BTO:0000671 Kidney BC H12817N BC Left Ventricle N41 Homo sapiens 3 left ventricle, donor N41, age 26, Asian, DNA extract mesoderm left ventricle normal M Myers BioChain D1234138_A705026 BTO:0001629 Left Ventricle BC N41 BC Leukocyte UHN00204 Homo sapiens 3 peripheral blood mononuclear cell, donor UHN00204, age 54, caucasian, DNA extract mesoderm blood normal M Myers BioChain D4234148_A612197 BTO:0001025 Leukocyte BC UHN00204 BC Liver 01-11002 Homo sapiens 3 liver, donor 01-11002, age 83, caucasian, DNA and RNA extract endoderm liver normal F Myers BioChain CP-S12-D1234149-05_B209118 BTO:0000759 Liver BC 01-11002 BC Lung 01-11002 Homo sapiens 3 lung, donor 01-11002, age 83, caucasian, DNA and RNA extract endoderm lung normal F Myers BioChain CP-S12-D1234152-05_A610240 BTO:0000763 Lung BC 01-11002 BC Lung H12817N Homo sapiens 3 lung, donor H12817N, age 71, caucasian, DNA and RNA extract endoderm lung normal M Myers BioChain CP-S13-D1234152-05_B402062 BTO:0000763 Lung BC H12817N BC Pancreas H12817N Homo sapiens 3 pancreas, donor H12817N, age 71, caucasian, DNA and RNA extract endoderm pancreas normal M Myers BioChain CP-S13-D1234188-05_B402063 BTO:0000988 Pancreas BC H12817N BC Penis H12817N Homo sapiens 3 penis, donor H12817N, age 71, caucasian, DNA extract mesoderm penis normal M Myers BioChain CP-S13-D1234194-05_B402064 BTO:0000405 Penis BC H12817N BC Pericardium H12529N Homo sapiens 3 pericardium, donor H12529N, age 70, caucasian, DNA extract mesoderm pericardium normal F Myers BioChain D1234133_A712271 BTO:0000717 Pericardium BC H12529N BC Placenta UHN00189 Homo sapiens 3 placenta, donor UHN00189, age 29 extraembryonic mesoderm, trophectoderm placenta normal F Myers BioChain D4234200_A603104 BTO:0001078 Placenta BC UHN00189 BC Prostate Gland H12817N Homo sapiens 3 prostate gland, donor H12817N, age 71, caucasian, DNA extract endoderm prostate gland normal M Myers BioChain CP-D1234201-05_B101058 BTO:0001129 Prostate Gland BC H12817N BC Rectum N29 Homo sapiens 3 rectum, donor N29, age 29, Asian, DNA extract endoderm rectum normal M Myers BioChain D4234206_A712205 BTO:0001158 Rectum BC N29 BC Skeletal Muscle 01-11002 Homo sapiens 3 skeletal muscle, donor 01-11002, age 83, caucasian, DNA and RNA extract mesoderm skeletal muscle normal F Myers BioChain CP-S12-D1234171-05_A610262 BTO:0001103 Skeletal Muscle BC 01-11002 BC Skeletal Muscle H12817N Homo sapiens 3 skeletal muscle, donor H12817N, age 71, caucasian, DNA and RNA extract mesoderm skeletal muscle normal M Myers BioChain CP-S13-D1234171-05_B402065 BTO:0001103 Skeletal Muscle BC H12817N BC Skin 01-11002 Homo sapiens 3 skin, donor 01-11002, age 83, caucasian, DNA extract ectoderm, mesoderm skin normal F Myers BioChain CP-S12-D1234218-05_B402066 BTO:0001253 Skin BC 01-11002 BC Small Intestine 01-11002 Homo sapiens 3 small intestine, donor 01-11002, age 83, caucasian, DNA and RNA extract endoderm small intestine normal F Myers BioChain CP-S12-D1234226-05_B402067 BTO:0000651 Small Intestine BC 01-11002 BC Spleen H12817N Homo sapiens 3 spleen, donor H12817N, age 71, caucasian, DNA and RNA extract mesoderm spleen normal M Myers BioChain CP-S13-D1234246-05_B402069 BTO:0001281 Spleen BC H12817N BC Stomach 01-11002 Homo sapiens 3 stomach, donor 01-11002, age 83, caucasian, DNA extract endoderm stomach normal F Myers BioChain CP-S12-D1234248-05_A808008 BTO:0001307 Stomach BC 01-11002 BC Stomach H12817N Homo sapiens 3 stomach, donor H12817N, age 71, caucasian, DNA and RNA extract endoderm stomach normal M Myers BioChain CP-S13-D1234248-05_B402070 BTO:0001307 Stomach BC H12817N BC Testis N30 Homo sapiens 3 testis, donor N30, age 41, Asian, DNA extract mesoderm testis normal M Myers BioChain D4234260_A711169 BTO:0001363 Testis BC N30 BC Uterus BN0765 Homo sapiens 3 uterus, donor BN0765, age 44, Asian, DNA extract uterus normal F Myers BioChain D4234274_A810099 BTO:0001424 Uterus BC BN0765 BE2 C Homo sapiens 3 neuroblastoma, BE-C is a clone of the SK-N-BE neuroblastoma cell line (see ATCC CRL-2271) that was established in November of 1972 from a bone marrow biopsy taken from a 2-year-old individual with disseminated neuroblastoma after repeated courses of chemotherapy and radiotherapy. ectoderm brain cancer M Stam ATCC CRL-2268 BTO:0001620 BE(2)-C BG02ES Homo sapiens 3 embryonic stem cell (hESC), BG02, treatment: H9 conditioned medium inner cell mass embryonic stem cell normal M Myers BresaGen, Inc. BG02 (hESBGN.02) BTO:0001086 BG02ES BG02ES-EBD Homo sapiens 3 embryonic stem cell (hESC), BG02, embryoid body-derived inner cell mass embryonic stem cell normal M Myers BresaGen, Inc. BG02 (hESBGN.02) BTO:0001086 BG02ES-EBD BJ Homo sapiens 3 skin fibroblast, "The line was established from skin taken from normal foreskin." - ATCC. (PMID: 9916803) skin normal M Stam ATCC CRL-2522 BTO:0001255 BJ bone marrow HS27a Homo sapiens 3 HS27a Human Marrow Stromal Cells are fibroblastoid cells immortalized with HPV16 E6/E7 genes as described in Roecklein and Torok-Storb, 1995 Blood 85:997-1005, insert DNA is LXSN-16 E6E7 packaged in PA31. bone marrow normal M Stam Dr. Beverly Torok-Storb at Fred Hutchison Cancer Research Center HS27a BTO:0000141 Bone Marrow HS27a bone marrow HS5 Homo sapiens 3 HS5 Human Marrow Stromal Cells are fibroblastoid cells immortalized with HPV16 E6/E7 genes as described in Roecklein and Torok-Storb, 1995 Blood 85:997-1005, insert DNA is LXSN-16 E6E7 packaged in PA31. bone marrow normal M Stam Dr. Beverly Torok-Storb at Fred Hutchison Cancer Research Center HS5 BTO:0000141 Bone Marrow HS27a bone marrow MSC Homo sapiens 3 These cells are primary fibroblastoid cells obtained from human bone marrow of normal donors as described in Roecklein and Torok-Storb, 1995 Blood 85:997-1005. bone marrow normal M Stam Dr. Beverly Torok-Storb at Fred Hutchison Cancer Research Center MSC BTO:0000141 Bone Marrow HS27a Breast OC Homo sapiens 3 Primary frozen breast tissue from NCTC donor IDs 11-0068A (Rep B1) and 11-0067A (Rep B2), both African American breast normal F Crawford NCTC 11-0068A BTO:0000149 Breast_OC Caco-2 Homo sapiens 3 colorectal adenocarcinoma. (PMID: 1939345) endoderm colon cancer M Stam ATCC HTB-37 BTO:0000195 Caco-2 CD34+ Mobilized Homo sapiens 3 hematopoietic progenitor cells- mobilized, from donor RO01679. blood M Stam Dr. Heimfeld Lab at FHCRC FHCRC BTO:0000725 CD34+ Mobilized CD4+ Naive Wb11970640 Homo sapiens 3 CD4+ naive sorted cells, donor is Caucasian, male 26 year old, primary pheresis of single normal subject mesoderm blood normal M Crawford Stam Dr. John Stamatoyannopoulos at UW Wb11970640 BTO:0000782 CD4+_Naive_Wb11970640 CD4+ Naive Wb78495824 Homo sapiens 3 CD4+ naive sorted cells, donor is Causasian, female 35 year old, primary pheresis of single normal subject mesoderm blood normal F Crawford Stam Dr. John Stamatoyannopoulos at UW Wb78495824 BTO:0000782 CD4+_Naive_Wb78495824 Cerebellum OC Homo sapiens 3 Primary frozen cerebellum tissue from NICHD donor IDs 1104 (Rep B1), 602 (Rep B2), 1442 (Rep B3), all Caucasian cerebellum normal M Crawford NICHD 1104 BTO:0000232 Cerebellum_OC Cerebrum frontal OC Homo sapiens 3 Primary frozen frontal cerebrum tissue from NICHD donor IDs 1104 (Rep B1), 602 (Rep B2), 1442 (Rep B3), all Caucasian frontal cerebrum normal M Crawford NICHD 1104 BTO:0000239 Cerebrum_frontal_OC Chorion Homo sapiens 3 chorion cells (outermost of two fetal membranes), fetal membranes were collected from women who underwent planned cesarean delivery at term, before labor and without rupture of membranes. extraembryonic mesoderm, trophectoderm fetal membrane U Crawford Dr. Amy Murtha at Duke University BTO:0000252 Chorion CLL Homo sapiens 3 chronic lymphocytic leukemia cell, T-cell lymphocyte mesoderm blood cancer F Crawford Dr. Jennifer Brown at Harvard Medical School. CLL BTO:0001546 CLL CMK Homo sapiens 3 acute megakaryocytic leukemia cells, "established from the peripheral blood of a 10-month-old boy with Down's syndrome and acute megakaryocytic leukemia (AML M7) at relapse in 1985" - DSMZ. (PMID: 3016165) mesoderm blood cancer M Stam DSMZ ACC-392 BTO:0004962 CMK Colo829 Homo sapiens 3 malignant melanoma skin cancer M Crawford ATCC CRL-1974 BTO:0000849 Colo829 Colon BC Homo sapiens 3 colon, parent cell type to donors BC_01-11002 and BC_H12817N endoderm colon normal B Myers BioChain CP-S12-D1234090-05_A903056 BTO:0000269 Colon BC Colon OC Homo sapiens 3 Primary frozen colon tissue from NCTC donor IDs 10-0005A (Rep B1) and 10-0170A (Rep B2), African American and caucasian colon normal B Crawford NCTC 10-0005A BTO:0000269 Colon OC Cord CD4 naive Homo sapiens 3 CD4+ cells isolated from cord blood and enriched for naive populations mesoderm blood normal B Crawford Stam Dr. David Randolph at University of Alabama, Birmingham Cord_CD4_naive BTO:0000782 T cells CD4+ naive cord blood Cord CD4 Th0 Homo sapiens 3 CD4+ cells isolated from cord blood and enriched for Th0 populations mesoderm blood normal B Crawford Dr. David Randolph at University of Alabama, Birmingham Cord_CD4_Th0 BTO:0000782 T cells CD4+ Th0 cord blood Cord CD4 Th1 Homo sapiens 3 CD4+ cells isolated from cord blood and enriched for Th1 populations mesoderm blood normal B Crawford Stam Dr. David Randolph at University of Alabama, Birmingham Cord_CD4_Th1 BTO:0000782 T cells CD4+ Th1 cord blood Decidua Homo sapiens 3 decidua cells (part of the mucous membrane lining uterus), Fetal membranes were collected from women who underwent planned cesarean delivery at term, before labor and without rupture of membranes decidua cervix F Crawford Dr. Amy Murtha at Duke University (Durham, NC). BTO:0001360 Decidua Dnd41 Homo sapiens 3 T cell leukemia with Notch mutation mesoderm blood cancer M Bernstein DSMZ Dnd41 BTO:0001106 Dnd41 ECC-1 Homo sapiens 3 epithelial cell line derived from an endometrium adenocarcinoma, fetal membranes were collected from women who underwent planned cesarean delivery at term, before labor and without rupture of membranes endoderm luminal epithelium cancer F Myers ATCC CRL-2923 BTO:0000194 ECC-1 Endometrium OC Homo sapiens 3 Endometrium isolated from uterine lining endometrium normal F Crawford Dr. Steven Young Endometrium_OC BTO:0001422 Endometrium OC Esophagus BC Homo sapiens 3 esophagus, parental cell type to donors 01-11002 and H12817N endoderm esophagus normal B Myers BioChain CP-S12-D1234106-05_A803198 BTO:0000959 Esophagus BC Fibrobl Homo sapiens 3 child fibroblast skin normal F Crawford Coriell AG08470 BTO:0000452 Fibrobl Fibrobl GM03348 Homo sapiens 3 skin fibroblast skin normal M Crawford Coriell GM03348 BTO:0001255 Fibrobl_GM03348 FibroP Homo sapiens 3 fibroblasts taken from individuals with Parkinson's disease, AG20443, AG08395 and AG08396 were pooled for this sample skin normal U Crawford Paul Tesar at Case Western University FibroP BTO:0000452 FibroP FibroP AG08395 Homo sapiens 3 fibroblasts taken from individuals with Parkinson's disease skin fibroblast F Crawford Coriell AG08395 BTO:0000452 FibroP_AG08395 FibroP AG08396 Homo sapiens 3 fibroblasts taken from individuals with Parkinson's disease lung fibroblast F Crawford Coriell AG08396 BTO:0000452 FibroP_AG08396 FibroP AG20443 Homo sapiens 3 fibroblasts taken from individuals with Parkinson's disease skin fibroblast M Crawford Coriell AG20443 BTO:0000452 FibroP_AG20443 Frontal cortex OC Homo sapiens 3 Primary ventromedial prefrontal cortex, from KPBBB donor IDs 673 (Rep B1) and 913 (Rep B2) frontal cortex normal F Crawford Kathleen Price Bryan Brain 673 BTO:0000484 Frontal cortex OC GC B cell Homo sapiens 3 Germinal center B cells (CD77+) isolated from de-identified tonsillectomy tonsil normal U Crawford Dr. Yanwen Jiang GC_B_cell BTO:0003671 GC_B_cell Gliobla Homo sapiens 3 glioblastoma, these cells (aka H54 and D54) come from a surgical resection from a patient with glioblastoma multiforme (WHO Grade IV). D54 is a commonly studied glioblastoma cell line (Bao et al., 2006) that has been thoroughly described by S Bigner (1981). (PMID: 7252524) ectoderm brain cancer U Crawford Dr. Darrell Bigner at Duke University Medical Center D54 BTO:0000527 Gliobla GM04503 Homo sapiens 3 adult twin pair fibroblasts, monozygotic twin of GM04504 skin normal F Stam Coriell GM04503D BTO:0001253 GM04503 GM04504 Homo sapiens 3 adult twin pair fibroblasts, monozygotic twin of GM04503, 13% of the cells examined show random chromosome loss skin normal F Stam Coriell GM04504A BTO:0001253 GM04504 GM06990 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah, treatment: Epstein-Barr Virus transformed mesoderm blood F Stam Coriell GM06990 BTO:0002062 (non-specific) GM06990 GM08714 Homo sapiens 3 lymphoblastoid cell line, Instability of heterochromatin of chromosomes 1, 9, and 16 with variable combined immunodeficiency; dysmorphic facial features, developmental delay, malabsorption, and recurrent infections; see GM08747 Fibroblast; donor subject is a compound heterozygote: one allele has a G>A transition at nucleotide 1807 (1807G>A) of the DNMT3B gene resulting in an Ala to Thr substitution at codon 603 [Ala603Thr (A603T)], the mutation occurring in a region between motifs I and IV within the catalytic domain of DNMT3B; the second allele has a G>A transition within intron 22 located 11 nucleotides 5-prime of the normal splice acceptor site [IVS22AS,G>A,-11] resulting in the generation of a novel splice acceptor site and a 9-bp insertion in the processed RNA. This results in the insertion of 3 amino acids (serine, threonine, and proline) at codon 744 (744ins3). The insertion was within the conserved region of the catalytic domain, which is likely to be disrupted by the insertion of a proline residue. This mutation was de novo. mesoderm blood F Farnham Coriell GM08714 BTO:0002062 GM08714 GM10248 Homo sapiens 3 lymphoblastoid cell line, Clinically normal; 4 paternal cousins have Cornelia de Lange syndrome; 46,XY, t(3;22)(q25.3;p12) mesoderm blood normal M Crawford Coriell GM10248 BTO:0002062 GM10248 GM10266 Homo sapiens 3 lymphoblastoid cell line, De Lange phenotype; developmental delay; profound retardation; seizures; 3 cousins are also affected; 46,XY,-22,+der (22)t(3;22)(q25.3;p12) mesoderm blood affected M Crawford Coriell GM10266 BTO:0002062 GM10266 GM10847 Homo sapiens 3 lymphoblastoid, International HapMap Project, CEPH/Utah, treatment: Epstein-Barr Virus transformed mesoderm blood F Snyder Coriell GM10847 BTO:0002062 (non-specific) GM10847 GM12801 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah, treatment: Epstein-Barr Virus transformed mesoderm blood M Stam Coriell GM12801 BTO:0002062 (non-specific) GM12801 GM12812 Homo sapiens 3 B-Lymphocyte, Lymphoblastoid, International HapMap Project, CEPH/Utah, Treatment: Epstein-Barr Virus transformed mesoderm blood M Stam Coriell GM12812 BTO:0002062 GM12812 GM12813 Homo sapiens 3 B-Lymphocyte, Lymphoblastoid, International HapMap Project, CEPH/Utah, Treatment: Epstein-Barr Virus transformed mesoderm blood F Stam Coriell GM12813 BTO:0002062 GM12813 GM12864 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed mesoderm blood M Stam Coriell GM12864 BTO:0002062 (non-specific) GM12864 GM12865 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed mesoderm blood F Stam Coriell GM12865 BTO:0002062 (non-specific) GM12865 GM12866 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed. mesoderm blood M Stam Coriell GM12866 BTO:0002062 (non-specific) GM12866 GM12867 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed. mesoderm blood F Stam Coriell GM12867 BTO:0002062 (non-specific) GM12867 GM12868 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed. mesoderm blood F Stam Coriell GM12868 BTO:0002062 (non-specific) GM12868 GM12869 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed. mesoderm blood F Stam Coriell GM12869 BTO:0002062 (non-specific) GM12869 GM12870 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed. mesoderm blood M Stam Coriell GM12870 BTO:0002062 (non-specific) GM12870 GM12871 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed. mesoderm blood M Stam Coriell GM12871 BTO:0002062 (non-specific) GM12871 GM12872 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed mesoderm blood M Stam Coriell GM12872 BTO:0002062 (non-specific) GM12872 GM12873 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed mesoderm blood F Stam Coriell GM12873 BTO:0002062 (non-specific) GM12873 GM12874 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed mesoderm blood M Stam Coriell GM12874 BTO:0002062 (non-specific) GM12874 GM12875 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1459, treatment: Epstein-Barr Virus transformed mesoderm blood F Stam Coriell GM12875 BTO:0002062 (non-specific) GM12875 GM12878-XiMat Homo sapiens 3 B-lymphocyte, lymphoblastoid, cloned for maternal X inactivation, International HapMap Project, CEPH/Utah, Epstein-Barr Virus mesoderm blood normal F Myers Hunt Willard at Duke University GM12878-XiMat BTO:0002062 GM12878-XiMat GM12891 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1463, treatment: Epstein-Barr Virus transformed mesoderm blood M Crawford Coriell GM12891 BTO:0002062 (non-specific) GM12891 GM12892 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, CEPH/Utah pedigree 1463, treatment: Epstein-Barr Virus transformed mesoderm blood F Crawford Coriell GM12892 BTO:0002062 (non-specific) GM12892 GM13976 Homo sapiens 3 lymphoblastoid cell line, clinically normal; monozygotic twin sister with Cornelia De Lange syndrome is GM13977 mesoderm blood normal F Crawford Coriell GM13976 BTO:0002062 GM13976 GM13977 Homo sapiens 3 lymphoblastoid cell line, Clinically affected; microcephaly; low frontal hairline; synophris; "penciled" arched eyebrows; short nose; crescent shaped mouth; hirsutism; micromelia; short thumbs; mental retardation; clinically normal monozygotic twin sister is GM13976 mesoderm blood affected F Crawford Coriell GM13977 BTO:0002062 GM13977 GM15510 Homo sapiens 3 lymphoblastoid NIGMS Human Genetic Cell Repository, DNA Polymorphism Discovery Resource Collection, treatment: Epstein-Barr Virus transformed mesoderm blood U Snyder Coriell GM15510 BTO:0002062 (non-specific) GM15510 GM18505 Homo sapiens 3 lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epstein-Barr Virus transformed mesoderm blood F Snyder Coriell GM18505 BTO:0002062 (non-specific) GM18505 GM18507 Homo sapiens 3 lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epstein-Barr Virus transformed mesoderm blood M ENCODE Coriell GM18507 BTO:0002062 (non-specific) GM18507 GM18526 Homo sapiens 3 lymphoblastoid, International HapMap Project, Han Chinese in Beijing, China, treatment: Epstein-Barr Virus transformed mesoderm blood F Snyder Coriell GM18526 BTO:0002062 (non-specific) GM18526 GM18951 Homo sapiens 3 lymphoblastoid, International HapMap Project, Japanese in Tokyo, Japan, treatment: Epstein-Barr Virus transformed mesoderm blood F Snyder Coriell GM18951 BTO:0002062 (non-specific) GM18951 GM19099 Homo sapiens 3 lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epstein-Barr Virus transformed mesoderm blood F Snyder Coriell GM19099 BTO:0002062 (non-specific) GM19099 GM19193 Homo sapiens 3 lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epstein-Barr Virus transformed mesoderm blood F Snyder Coriell GM19193 BTO:0002062 (non-specific) GM19193 GM19238 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epstein-Barr Virus transformed mesoderm blood F Crawford Coriell GM19238 BTO:0002062 (non-specific) GM19238 GM19239 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epstein-Barr Virus transformed mesoderm blood M Crawford Coriell GM19239 BTO:0002062 (non-specific) GM19239 GM19240 Homo sapiens 3 B-lymphocyte, lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epstein-Barr Virus transformed mesoderm blood F Crawford Coriell GM19240 BTO:0002062 (non-specific) GM19240 GM20000 Homo sapiens 3 lymphoblastoid cell line, De Lange phenotype; developmental delay; profound retardation mesoderm blood affected M Crawford Coriell GM20000 BTO:0002062 GM20000 H0287 Homo sapiens 3 EBV-transformed lymphoblastoid cell line (LCL) was derived from peripheral blood donated by a normal healthy male. mesoderm blood normal M Stam Dr. John Stamatoyannopoulos at UW H0287 BTO:0002807 H0287 H7-hESC Homo sapiens 3 undifferentiated embryonic stem cells inner cell mass U StamAndCrawford WiCell Research Institute WA07 (H7) BTO:0001086 H7-hESC H9ES Homo sapiens 3 embryonic stem cell (hESC) H9 inner cell mass embryonic stem cell F Myers WiCell Research Institute WA09 (H9) BTO:0001086 H9ES H9ES-AFP+ Homo sapiens 3 embryonic stem cell (hESC), H9-derived, treatment: H9 AFP+ inner cell mass embryonic stem cell F Myers WiCell Research Institute WA09 (H9) BTO:0001086 H9ES-AFP+ H9ES-AFP- Homo sapiens 3 embryonic stem cell (hESC), H9-derived, treatment: H9 AFP- inner cell mass embryonic stem cell F Myers WiCell Research Institute WA09 (H9) BTO:0001086 H9ES-AFP- H9ES-CM Homo sapiens 3 embryonic stem cell (hESC) H9, treatment: H9 conditioned medium inner cell mass embryonic stem cell F Myers WiCell Research Institute WA09 (H9) BTO:0001086 H9ES-CM H9ES-E Homo sapiens 3 embryonic stem cell (hESC) H9, endoderm inner cell mass embryonic stem cell F Myers WiCell Research Institute WA09 (H9) BTO:0001086 H9ES-E H9ES-EB Homo sapiens 3 embryonic stem cell (hESC) H9, embryoid bodies inner cell mass embryonic stem cell F Myers WiCell Research Institute WA09 (H9) BTO:0001086 H9ES-EB H9ES-EBD Homo sapiens 3 embryonic stem cell (hESC) H9, embryoid body-derived inner cell mass embryonic stem cell F Myers WiCell Research Institute WA09 (H9) BTO:0001086 H9ES-EBD HA-h Homo sapiens 3 astrocytes-hippocampal ectoderm brain hippocampus normal U Stam ScienCell 1830 BTO:0000099 HA-h HA-sp Homo sapiens 3 astrocytes spinal cord ectoderm spinal cord normal U Stam ScienCell 1820 BTO:0000099 HA-sp HAc Homo sapiens 3 astrocytes-cerebellar ectoderm cerebellar normal U Stam ScienCell 1810 BTO:0000099 HAc HAEpiC Homo sapiens 3 amniotic epithelial cells epithelium normal U Stam ScienCell 7110 BTO:0004660 HAEpiC HAL Homo sapiens 3 adult liver, genomic DNA purified from surgically excised adult human liver endoderm liver U Myers Asterand, Inc. HAL BTO:0000759 HAL HAoAF Homo sapiens 3 Aortic Adventitial Fibroblasts from two individuals, HAoAF_6090101.11 and HAoAF_6111301.9 from tunica adventitia mesoderm blood vessel normal B Gingeras PromoCell HAoAF BTO:0000135 HAoAF HAoAF 6090101.11 Homo sapiens 3 Aortic Adventitial Fibroblasts from tunica adventitia mesoderm blood vessel normal M Gingeras PromoCell C-14037 BTO:0000135 HAoAF_6090101.11 HAoAF 6111301.9 Homo sapiens 3 Aortic Adventitial Fibroblasts from tunica adventitia mesoderm blood vessel normal F Gingeras PromoCell C-14037 BTO:0000135 HAoAF_6111301.9 HAoEC Homo sapiens 3 Aortic Endothelial Cells (thoracic) from two individuals, HAoEC_7071706.1 and HAoEC_8061102.1 mesoderm blood vessel normal B Gingeras PromoCell HAoEC BTO:0000394 HAoEC HAoEC 7071706.1 Homo sapiens 3 Aortic Endothelial Cells mesoderm blood vessel normal F Gingeras PromoCell C-14023 BTO:0000394 HAoEC_7071706.1 HAoEC 8061102.1 Homo sapiens 3 Aortic Endothelial Cells from throracic mesoderm blood vessel normal M Gingeras PromoCell C-14023 BTO:0000394 HAoEC_8061102.1 HBMEC Homo sapiens 3 brain microvascular endothelial cells mesoderm blood vessel normal U Stam ScienCell 1000 BTO:0003636 HBMEC HBVP Homo sapiens 3 brain vascular pericytes mesoderm blood vessel normal U Stam ScienCell 1200 BTO:0002441 HBVP HBVSMC Homo sapiens 3 brain vascular smooth muscle cells. mesoderm blood vessel normal F Stam ScienCell 1100 BTO:0002488 HBVSMC HCF Homo sapiens 3 cardiac fibroblasts mesoderm heart normal U Stam ScienCell 6300 BTO:0003093 HCF HCFaa Homo sapiens 3 cardiac fibroblasts- adult atrial mesoderm heart normal F Stam ScienCell 6320 BTO:0003093 HCFaa HCH Homo sapiens 3 Undifferentiated Chondrocytes from two individuals, HCH_8100808.2 and HCH_0011308.2P from knee joint missing cartilage normal M Gingeras PromoCell HCH BTO:0000249 HCH HCH 0011308.2P Homo sapiens 3 Undifferentiated Chondrocytes from knee joint missing cartilage normal F Gingeras PromoCell C-14070 BTO:0000249 HCH_0011308.2P HCH 8100808.2 Homo sapiens 3 Undifferentiated Chondrocytes from knee joint missing cartilage normal M Gingeras PromoCell C-14070 BTO:0000249 HCH_8100808.2 HCM Homo sapiens 3 cardiac myocytes mesoderm heart normal U Stam ScienCell 6200 BTO:0001539 HCM HConF Homo sapiens 3 conjunctival fibroblast ectoderm eye U Stam ScienCell 6570 BTO:0003415 HConF HCPEpiC Homo sapiens 3 choroid plexus epithelial cells ectoderm epithelium normal U Stam ScienCell 1310 BTO:0000258 HCPEpiC HCT-116 Homo sapiens 3 colorectal carcinoma (PMID: 7214343) endoderm colon cancer M ENCODE ATCC CCL-247 BTO:0002254 HCT-116 Heart OC Homo sapiens 3 Primary frozen heart tissue from NICHD donor IDs 1104 (Rep B1 DNase), 602 (Rep B2 DNase), 1442 (Rep B3 DNase), 1863 (Rep B1 FAIRE), 4548 (Rep B2 FAIRE) heart normal B Crawford NICHD 1104 BTO:0000562 Heart_OC Heart STL003 Homo sapiens 3 Standard procurement of heart tissue from a 34 year old caucasian male. heart normal M Snyder lab STL003 BTO:0000562 Heart_STL003 HEEpiC Homo sapiens 3 esophageal epithelial cells endoderm epithelium normal U Stam ScienCell 2720 BTO:0001578 HEEpiC HEK293 Homo sapiens 3 embryonic kidney, cells contain Adenovirus 5 DNA (PMID: 11967234) mesoderm kidney U Stam ATCC CRL-1573 BTO:0000007 HEK293 HEK293-T-REx Homo sapiens 3 embryonic kidney cells transformed with Adenovirus 5 DNA stably expressing tetracycline repressor, HEK293 (ATCC number CRL-1573) is the parental cell line, hypotriploid, XXX mesoderm kidney F Farnham Invitrogen r71007 BTO:0000007 HEK293-T-REx HEK293T Homo sapiens 3 embryonic kidney that expresses SV40 large T antigen, HEK293 (ATCC number CRL-1573) is the parental cell line mesoderm kidney F Crawford Thermo Scientific Open Biosystems HCL4517 BTO:0000007 HEK293T Hepatocytes Homo sapiens 3 primary hepatocytes, liver perfused by enzymes to generate single cell suspension endoderm liver normal B Crawford zen-bio Missing BTO:0000575 Hepatocytes HFDPC Homo sapiens 3 Follicle Dermal Papilla Cells from two individuals, HFDPC_0100503.2 and HFDPC_0102703.3 from lateral scalp (brown, blond) missing skin normal F Gingeras PromoCell HFDPC BTO:0001849 HFDPC HFDPC 0100503.2 Homo sapiens 3 Follicle Dermal Papilla Cells from lateral scalp (brown) missing skin normal F Gingeras PromoCell C-14005 BTO:0001849 HFDPC_0100503.2 HFDPC 0102703.3 Homo sapiens 3 Follicle Dermal Papilla Cells from lateral scalp (blond) missing skin normal F Gingeras PromoCell C-14005 BTO:0001849 HFDPC_0102703.3 HFF Homo sapiens 3 foreskin fibroblast foreskin normal M Stam Dr. Beverly Torok-Storb at Fred Hutchison Cancer Research Center HFF BTO:0002245 HFF HFF-Myc Homo sapiens 3 foreskin fibroblast cells expressing canine cMyc fibroblast foreskin normal M Stam Dr. Beverly Torok-Storb at Fred Hutchison Cancer Research Center HFF-Myc BTO:0002245 HFF-Myc HFL11W Homo sapiens 3 fetal liver 11 weeks, consented fetal liver samples were isolated from legally aborted fetuses at 11 weeks gestation endoderm liver U ENCODE Unknown HFL11W BTO:0000759 HFL11W HFL24W Homo sapiens 3 fetal liver 24 weeks, consented fetal liver samples were isolated from legally aborted fetuses at 24 weeks gestation endoderm liver U Myers Unknown HFL24W BTO:0000759 HFL24W HGF Homo sapiens 3 gingival fibroblasts gingiva normal U Stam ScienCell 2620 BTO:0000519 (non-specific) HGF HHSEC Homo sapiens 3 hepatic sinusoidal endothelial cells endoderm liver U Stam ScienCell 5000 BTO:0001251 HHSEC HIPEpiC Homo sapiens 3 iris pigment epithelial cells ectoderm epithelium normal U Stam ScienCell 6560 BTO:0000653 HIPEpiC HL-60 Homo sapiens 3 promyelocytic leukemia cells, (PMID: 276884) mesoderm blood cancer F Stam ATCC CCL-240 BTO:0000738 HL-60 HMEC Homo sapiens 3 mammary epithelial cells ectoderm breast normal U Bernstein Lonza CC-2551 BTO:0002178 HMEC HMEpC Homo sapiens 3 Mammary Epithelial Cells (placeholder, waiting on second lot/donor from PromoCell) ectoderm mammary gland normal F Gingeras PromoCell HMEpC BTO:0002178 HMEpC HMEpC 6022801.3 Homo sapiens 3 Mammary Epithelial Cells ectoderm mammary gland normal F Gingeras PromoCell C-14066 BTO:0002178 HMEpC_6022801.3 HMF Homo sapiens 3 mammary fibroblasts mammary F Stam ScienCell 7630 BTO:0000817 HMF hMNC-CB Homo sapiens 3 Mononuclear Cells (umbilical cord blood-single donor) from two individuals, hMNC-CB_9111701.6 and hMNC-CB_8072802.6 missing blood normal B Gingeras PromoCell hMNC-CB BTO:0004054 hMNC-CB hMNC-CB 8072802.6 Homo sapiens 3 Mononuclear Cells, umbilical cord blood-single donor missing blood normal M Gingeras PromoCell C-14096 BTO:0004054 hMNC-CB_8072802.6 hMNC-CB 9111701.6 Homo sapiens 3 Mononuclear Cells, umbilical cord blood-single donor missing blood normal F Gingeras PromoCell C-14096 BTO:0004054 hMNC-CB_9111701.6 hMNC-PB Homo sapiens 3 Mononuclear Cells (peripheral blood-single donor) from two individuals, hMNC-PB_0022330.9 and hMNC-PB_0082430.9 missing blood normal B Gingeras PromoCell hMNC-PB BTO:0001025 hMNC-PB hMNC-PB 0022330.9 Homo sapiens 3 Mononuclear Cells, peripheral blood-single donor missing blood normal M Gingeras PromoCell C-14098 BTO:0001025 hMNC-PB_0022330.9 hMNC-PB 0082430.9 Homo sapiens 3 Mononuclear Cells, peripheral blood-single donor missing blood normal F Gingeras PromoCell C-14098 BTO:0001025 hMNC-PB_0082430.9 hMSC-AT Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from two individuals, hMSC-AT_9061601.12 and hMSC-AT_0102604.12 from subcutaneous abdomen adipose tissue missing adipose normal F Gingeras PromoCell hMSC-AT BTO:0003298 hMSC-AT hMSC-AT 0102604.12 Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from subcutaneous abdomen adipose tissue missing adipose normal F Gingeras PromoCell C-14092 BTO:0003298 hMSC-AT_0102604.12 hMSC-AT 9061601.12 Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from abdomen missing subcutaneous adipose tissue normal F Gingeras PromoCell C-14092 BTO:0003298 hMSC-AT_9061601.12 hMSC-BM Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from two individuals, hMSC-BM_0050602.11 and hMSC-BM_0051105.11 from femoral head missing bone marrow normal B Gingeras PromoCell hMSC-BM BTO:0003298 hMSC-BM hMSC-BM 0050602.11 Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from femoral head missing bone marrow normal M Gingeras PromoCell C-14090 BTO:0003298 hMSC-BM_0050602.11 hMSC-BM 0051105.11 Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from femoral head missing bone marrow normal F Gingeras PromoCell C-14090 BTO:0003298 hMSC-BM_0051105.11 hMSC-UC Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from two individuals, hMSC-UC_0081101.7 and hMSC-UC_0052501.7 from matrix (Wharton's Jelly) missing umbilical cord normal B Gingeras PromoCell hMSC-UC BTO:0003298 hMSC-UC hMSC-UC 0052501.7 Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from matrix (Wharton's Jelly) missing umbilical cord normal M Gingeras PromoCell C-14091 BTO:0003298 hMSC-UC_0052501.7 hMSC-UC 0081101.7 Homo sapiens 3 Undifferentiated Mesenchymal Stem Cells from matrix (Wharton's Jelly) missing umbilical cord normal F Gingeras PromoCell C-14091 BTO:0003298 hMSC-UC_0081101.7 HMVEC-dAd Homo sapiens 3 adult dermal microvascular endothelial cells. blood vessel normal F Stam Lonza CC-2543,CC-3202 BTO:0001854 HMVEC-dAd HMVEC-dBl-Ad Homo sapiens 3 adult blood microvascular endothelial cells, dermal-derived mesoderm blood vessel normal F Stam Lonza CC-2811, CC-2811T75 BTO:0004574 HMVEC-dBl-Ad HMVEC-dBl-Neo Homo sapiens 3 neonatal blood microvascular endothelial cells, dermal-derived mesoderm blood vessel normal M Stam Lonza CC-2813, CC-2813T75 BTO:0004574 HMVEC-dBl-Neo HMVEC-dLy-Ad Homo sapiens 3 adult lymphatic microvascular endothelial cells, dermal-derived mesoderm blood vessel normal F Stam Lonza CC-2810, CC-2810T75 BTO:0004574 HMVEC-dLy-Ad HMVEC-dLy-Neo Homo sapiens 3 neonatal lymphatic microvascular endothelial cells, dermal-derived mesoderm blood vessel normal M Stam Lonza CC-2812, CC-2812T25 BTO:0004574 HMVEC-dLy-Neo HMVEC-dNeo Homo sapiens 3 neonatal microvascular endothelial cells (single donor), dermal-derived mesoderm blood vessel normal M Stam Lonza CC-2505, CC-2505T225 BTO:0004574 HMVEC-dNeo HMVEC-LBl Homo sapiens 3 blood microvascular endothelial cells, lung-derived mesoderm blood vessel normal F Stam Lonza CC-2815, CC-2815T75 BTO:0003599 HMVEC-LBl HMVEC-LLy Homo sapiens 3 lymphatic microvascular endothelial cells, lung-derived mesoderm blood vessel normal F Stam Lonza CC-2814, CC-2814T25 BTO:0003599 HMVEC-LLy HNPCEpiC Homo sapiens 3 non-pigment ciliary epithelial cells epithelium normal U Stam ScienCell 6580 BTO:0001770 HNPCEpiC HOB Homo sapiens 3 Undifferentiated Osteoblasts from two individuals, HOB_0090202.1 and HOB_0091301 from femoral head missing cancellous bone normal M Gingeras PromoCell HOB BTO:0004324 HOB HOB 0090202.1 Homo sapiens 3 Undifferentiated Osteoblasts from femoral head missing cancellous bone normal M Gingeras PromoCell C-14071 BTO:0004324 HOB_0090202.1 HOB 0091301 Homo sapiens 3 Undifferentiated Osteoblasts from femoral head missing cancellous bone normal F Gingeras PromoCell C-14071 BTO:0004324 HOB_0091301 HPAEC Homo sapiens 3 pulmonary artery endothelial cells. mesoderm blood vessel normal F Stam Lonza CC-2530,CC-3162 BTO:0001141 HPAEC HPAEpiC Homo sapiens 3 pulmonary alveolar epithelial cells epithelium normal U Stam ScienCell 3200 BTO:0003511 HPAEpiC HPAF Homo sapiens 3 pulmonary artery fibroblasts mesoderm blood vessel normal U Stam ScienCell 3120 BTO:0000778 HPAF HPC-PL Homo sapiens 3 Undifferentiated Pericytes from HPC-PL_0032601.13 and HPC-PL_0101504.13 missing placenta normal B Gingeras PromoCell pericytes BTO:0001975 HPC-PL HPC-PL 0032601.13 Homo sapiens 3 Undifferentiated Pericytes missing placenta normal M Gingeras PromoCell C-14095 BTO:0001975 HPC-PL_0032601.13 HPC-PL 0101504.13 Homo sapiens 3 Undifferentiated Pericytes missing placenta normal F Gingeras PromoCell C-14095 BTO:0001975 HPC-PL_0101504.13 HPDE6-E6E7 Homo sapiens 3 pancreatic duct cells immortalized with E6E7 gene of HPV endoderm pancreatic duct normal F Crawford Dr. Ming-Sound Tsao, Ontario Cancer Institute HPDE6-E6E7 BTO:0002362 HPDE6-E6E7 HPdLF Homo sapiens 3 periodontal ligament fibroblasts epithelium normal M Stam Lonza CC-7049 BTO:0001020 HPdLF HPF Homo sapiens 3 pulmonary fibroblasts isolated from lung tissue lung normal U Stam ScienCell 3300 BTO:0000764 HPF HPIEpC Homo sapiens 3 Placental Epithelial Cells amniotic membrane missing placenta normal B Gingeras PromoCell human-placental-epithelial-cells-hplepc BTO:0001975 HPIEpC HPIEpC 9012801.2 Homo sapiens 3 Placental Epithelial Cells amniotic membrane missing placenta normal F Gingeras PromoCell C-14069 BTO:0001975 HPIEpC_9012801.2 HPIEpC 9041503.2 Homo sapiens 3 Placental Epithelial Cells amniotic membrane missing placenta normal M Gingeras PromoCell C-14069 BTO:0001975 HPIEpC_9041503.2 HRCEpiC Homo sapiens 3 renal cortical epithelial cells mesoderm epithelium normal U Stam Lonza CC-2554 BTO:0000059 (non-specific) HRCEpiC HRE Homo sapiens 3 renal epithelial cells mesoderm epithelium normal U Stam Lonza CC-2556 BTO:0000059 (non-specific) HRE HRGEC Homo sapiens 3 renal glomerular endothelial cells mesoderm kidney normal U Stam ScienCell 4000 BTO:0001176 HRGEC HRPEpiC Homo sapiens 3 retinal pigment epithelial cells ectoderm epithelium normal U Stam ScienCell 6540 BTO:0001177 HRPEpiC HSaVEC Homo sapiens 3 Saphenous Vein Endothelial Cells from two individuals, HSaVEC_9100101.15 and HSaVEC_0022202.16 from thigh mesoderm blood vessel normal M Gingeras PromoCell HSaVEC BTO:0003275 HSaVEC HSaVEC 0022202.16 Homo sapiens 3 Saphenous Vein Endothelial Cells from thigh mesoderm blood vessel normal M Gingeras PromoCell C-14025 BTO:0003275 HSaVEC_0022202.16 HSaVEC 9100101.15 Homo sapiens 3 Saphenous Vein Endothelial Cells from thigh mesoderm blood vessel normal M Gingeras PromoCell C-14025 BTO:0003275 HSaVEC_9100101.15 HSMM Homo sapiens 3 skeletal muscle myoblasts mesoderm muscle normal U Bernstein Refer to the protocol documents for differing sources CC-2580 BTO:0000256 (non-specific) HSMM HSMM emb Homo sapiens 3 embryonic myoblast muscle U Crawford Duke/UNC/UT/EBI ENCODE group fetal myoblast cell strain (H246 and H275) from Dr Stephen Hauschka- U. of Washington 1980 BTO:0000222 HSMM_emb HSMM FSHD Homo sapiens 3 primary myoblast from Facioscapulohumeral Muscular Dystrophy (FSHD) patients, muscle needle biopsies muscle U Crawford Duke/UNC/UT/EBI ENCODE group HSMM_FSHD BTO:0000222 HSMM_FSHD HSMMtube Homo sapiens 3 skeletal muscle myotubes differentiated from the HSMM cell line mesoderm muscle normal U Bernstein Lonza See HSMM BTO:0001760 (non-specific) HSMMtube HSMMtube emb Homo sapiens 3 embryonic myotube muscle U Crawford Duke/UNC/UT/EBI ENCODE group fetal myoblast cell strain (H246 and H275) from Dr Stephen Hauschka- U. of Washington 1980 BTO:0001760 HSMMtube_emb HSMMtube FSHD Homo sapiens 3 myotube from Facioscapulohumeral Muscular Dystrophy (FSHD) patient, muscle needle biopsies muscle U Crawford Duke/UNC/UT/EBI ENCODE group HSMMtube_FSHD BTO:0001760 HSMMtube_FSHD HT-1080 Homo sapiens 3 epithelial cell line derived from a fibrosarcoma, (PMID: 4132053), pseudo-diploid male with a modal chromosome number of 46, numerous chromosome abnormalities mesoderm epithelium cancer M missing ATCC CCL-121 BTO:0001282 HT-1080 HTR8svn Homo sapiens 3 trophoblast (HTR-8/SVneo) cell line, a thin layer of ectoderm that forms the wall of many mammalian blastulas and functions in the nutrition and implantation of the embryo ectoderm blastula normal F Crawford Charles H. Graham, Department of Anatomy & Cell Biology, Queen's University at Kingston, Kingston, Ontario, Canada HTR8svn BTO:0001079 HTR8svn Huh-7 Homo sapiens 3 hepatocellular carcinoma endoderm liver cancer M Crawford Dr. Ravi Jhaveri at Duke University Huh-7 BTO:0001950 Huh-7 Huh-7.5 Homo sapiens 3 hepatocellular carcinoma, hepatocytes selected for high levels of hepatitis C replication endoderm liver cancer M Crawford Dr. Ravi Jhaveri at Duke University Huh-7.5 BTO:0001950 Huh-7.5 HVMF Homo sapiens 3 villous mesenchymal fibroblast cells connective normal U Stam ScienCell 7130 BTO:0002625 HVMF HVMF 6091203.3 Homo sapiens 3 Villous Mesenchymal Fibroblasts from villous tissue missing placenta normal M Gingeras PromoCell C-14034 BTO:0001975 HVMF_6091203.3 HVMF 6100401.3 Homo sapiens 3 Villous Mesenchymal Fibroblasts from villous tissue missing placenta normal F Gingeras PromoCell C-14034 BTO:0001975 HVMF_6100401.3 HWP Homo sapiens 3 Undifferentiated White Preadipocytes from two individuals, HWP_0092205 and HWP_8120201.5, subcutaneous adipose tissue from abdomen / upper arm missing adipose normal B Gingeras PromoCell HWP BTO:0004042 HWP HWP 0092205 Homo sapiens 3 Undifferentiated White Preadipocytes from abdomen missing subcutaneous adipose tissue normal M Gingeras PromoCell C-14072 BTO:0004042 HWP_0092205 HWP 8120201.5 Homo sapiens 3 Undifferentiated White Preadipocytes from upper arm missing subcutaneous adipose tissue normal F Gingeras PromoCell C-14072 BTO:0004042 HWP_8120201.5 iPS Homo sapiens 3 induced pluripotent stem cell derived from skin fibroblast induced pluripotent stem cell derived from skin fibroblast induced pluripotent stem cell B Crawford Josh Chenoweth, Laboratory of Molecular Biology, National Institutes of Health, NINDS iPS BTO:0000001 (nonspecific) iPS iPS CWRU1 Homo sapiens 3 iPS cells derived from MSC658 fibroblast induced pluripotent cell (iPS) M Crawford Paul Tesar at Case Western University iPS_CWRU1 BTO:0000001 iPS_CWRU1 iPS hFib2 iPS4 Homo sapiens 3 induced pluripotent stem cell line 4 derived from skin fibroblast of a 30 year old donor, same donor as iPS_hFib2_iPS5 missing induced pluripotent cell (iPS) normal M Gilbert HSCI iPS Cell Core Facility hFib2_iPS4 BTO:0000001 iPS_hFib2_iPS4 iPS hFib2 iPS5 Homo sapiens 3 induced pluripotent stem cell line 5 derived from skin fibroblast of a 30 year old donor, same donor as iPS_hFib2_iPS4 missing induced pluripotent cell (iPS) normal M Gilbert HSCI iPS Cell Core Facility hFib2_iPS5 BTO:0000001 iPS_hFib2_iPS5 iPS NIHi11 Homo sapiens 3 iPS cells derived from AG20443 fibroblast induced pluripotent cell (iPS) M Crawford Josh Chenoweth, Laboratory of Molecular Biology, National Institutes of Health, NINDS iPS_NIHi11 BTO:0000001 iPS_NIHi11 iPS NIHi7 Homo sapiens 3 iPS cells derived from AG08395 fibroblast induced pluripotent cell (iPS) F Crawford Josh Chenoweth, Laboratory of Molecular Biology, National Institutes of Health, NINDS iPS_NIHi7 BTO:0000001 iPS_NIHi7 Ishikawa Homo sapiens 3 endometrial adenocarcinoma uterus F Crawford Sigma-Aldrich 99040201 BTO:0000658 Ishikawa Jurkat Homo sapiens 3 T lymphoblastoid derived from an acute T cell leukemia, "The Jurkat cell line was established from the peripheral blood of a 14 year old boy by Schneider et al., and was originally designated JM." - ATCC. (PMID: 68013) mesoderm blood cancer M Myers ATCC TIB-152 BTO:0001948 Jurkat Kidney BC Homo sapiens 3 kidney, parental cell type to donors 01-11002 and H12817N mesoderm kidney normal B Myers BioChain CP-S12-D1234142-05_B402060 BTO:0000671 Kidney BC Kidney OC Homo sapiens 3 Primary frozen kidney tissue from NICHD donor IDs 1104 (Rep B1 DNase), 602 (Rep B2 DNase), 1442 (Rep B3 DNase), 1863 (Rep B3 FAIRE) and NCTC donor ID 10-0022A (Rep B1 FAIRE) kidney normal B Crawford NICHD 1104 BTO:0000671 Kidney OC LHSR Homo sapiens 3 prostate epithelial cells (PrEC), multiple human donors, all of whom are HIV-1, Hepatitis B and Hepatitis C negative, treatment: to create LHSR, cells were infected with amphotropic retroviruses encoding the SV40 large T antigen (L), the telomerase catalytic subunit hTERT (H), the SV40 small T antigen (S) and an oncogenic allele of H-ras (R). endoderm epithelium normal U Crawford William Hahn at the Dana Farber Cancer Institute, Boston, MA LHSR BTO:0002398 LHSR Liver OC Homo sapiens 3 Primary frozen liver tissue from NICHD donor IDs 1104 (Rep B1), 602 (Rep B2), 1442 (Rep B3) liver normal M Crawford NICHD 1104 BTO:0000759 Liver_OC Liver STL004 Homo sapiens 3 Primary liver tissue from the right portion of a standard liver procurement from a 6 year old female. liver normal F Snyder lab STL004 BTO:0000759 Liver_STL004 Liver STL011 Homo sapiens 3 Primary liver tissue of a standard liver procurement from a 36 year old caucasian male. liver normal M Snyder lab STL011 BTO:0000759 Liver_STL011 LNCaP Homo sapiens 3 prostate adenocarcinoma, "LNCaP clone FGC was isolated in 1977 by J.S. Horoszewicz, et al., from a needle aspiration biopsy of the left supraclavicular lymph node of a 50-year-old caucasian male (blood type B+) with confirmed diagnosis of metastatic prostate carcinoma." - ATCC. (Horoszewicz et al. LNCaP Model of Human Prostatic Carcinoma. Cancer Research 43, 1809-1818, April 1983.) endoderm prostate cancer M Crawford ATCC CRL-1740 BTO:0002021 LNCaP Loucy Homo sapiens 3 T cell leukemia mesoderm blood cancer F Bernstein DSMZ Loucy BTO:0002104 Loucy Lung BC Homo sapiens 3 lung, parental cell type to donors 01-11002 and H12817N endoderm lung normal B Myers BioChain CP-S12-D1234152-05_A610240 BTO:0000763 Lung BC Lung OC Homo sapiens 3 Primary frozen lung tissue from NICHD donor IDs 1104 (Rep B1 DNase), 602 (Rep B2 DNase), 1442 (Rep B3 DNase) and CF Center donor IDs DD006I (Rep B1 FAIRE) and DD007I (Rep B2 FAIRE) Lung normal B Crawford NICHD 1104 BTO:0000763 Lung_OC Lymphoblastoid cell line Homo sapiens 3 parental cell type to lymphoblastoid cell lines mesoderm blood normal B Stam Coriell various GMXXXXX cell lines BTO:0002062 (non-specific) Lymphoblastoid_cell_line M059J Homo sapiens 3 malignant glioblastoma, glioma, lack DNA-dependent protein kinase activity, deficient in repair of DNA double strand breaks, the cells are negative for glial fibrillary acidic protein (GFAP), tumor specimen taken from a 33 year old ectoderm brain cancer M Stam ATCC CRL-2366 BTO:0000527 M059J MCF10A-Er-Src Homo sapiens 3 mammary gland, non-tumorigenic epithelial, inducible cell line, derived from the MCF-10A parental cells and contain ER-Src, a derivative of the Src kinase oncoprotein (v-Src) that is fused to the ligand-binding domain of the estrogen receptor (ER) ectoderm breast F Struhl Struhl laboratory MCF10A-Er-Src BTO:0001939 MCF10A-Er-Src MDA-MB-231 Homo sapiens 3 breast adenocarcinoma, epithelial cell line, derived from metastatic site: pleural effusion. (PMID: 730202) ectoderm breast cancer F Struhl ATCC HTB-26 BTO:0000815 MDA-MB-231 Medullo Homo sapiens 3 medulloblastoma (aka D721), surgical resection from a patient with medulloblastoma as described by Darrell Bigner (1997) ectoderm brain cancer U Crawford Dr. Darrell Bigner at Duke University Medical Center BTO:0001359 Medullo Medullo D341 Homo sapiens 3 Medulloblastoma cell line of neuron or neuron precurosr origin brain cancer U Crawford Dr. Darrell Bigner at Duke University Medical Center Medullo_D341 BTO:0001757 Medullo_D341 Mel 2183 Homo sapiens 3 Melanoma Cell line Melanoma cell line derived from melanoma metastasis cancer U Crawford Dr. Yardena Samuels Mel_2183 BTO:0000849 Mel_2183 Melano Homo sapiens 3 epidermal melanocytes ectoderm skin normal U Crawford ScienCell 2200 BTO:0000847 Melano MRT A204 Homo sapiens 3 Malignant rhabdoid tumor (MRT) line, rhabdomyosarcoma missing muscle cancer F Crawford ATCC HTB-82 BTO:0002062 MRT A204 MRT G401 Homo sapiens 3 Malignant renal rhabdoid tumor line missing kidney cancer M Crawford ATCC CRL-1441 BTO:0002062 MRT G401 MRT TTC549 Homo sapiens 3 Malignant Hepatic Rhabdoid tumor line missing liver cancer M Crawford ATCC TTC549 BTO:0002062 MRT TTC549 Myometr Homo sapiens 3 myometrial cells myometrium normal F Crawford Dr. Jennifer Condon of Magee Women's Research Institute BTO:0000907 Myometr Naive B cell Homo sapiens 3 Naive B cells (IgD+) isolated from de-identified tonsillectomy tonsil normal U Crawford Dr. Yanwen Jiang Naive_B_cell BTO:0000776 Naive_B_cell NB4 Homo sapiens 3 acute promyelocytic leukemia cell line. (PMID: 1995093) mesoderm blood cancer U ENCODE Refer to protocol documents for differing sources, UW: DSMZ (Deutsche Sammlung von Mikroorganismen und Zellkulturen) ACC-207 http://www.dsmz.de/ or Yale (Stanford): National Cell Culture Center http://www.nccc.com/ NB4 BTO:0002489 NB4 NH-A Homo sapiens 3 astrocytes (also called Astrocy) ectoderm brain normal U Bernstein Lonza CC-2565 BTO:0000099 NH-A NHBE Homo sapiens 3 bronchial epithelial cells endoderm epithelium normal F Crawford Lonza CC-2541 BTO:0002022 NHBE NHBE RA Homo sapiens 3 bronchial epithelial cells with retinoic acid bronchial epithelium normal F UW Stam Lonza CC-2540, CC3170 BTO:0001845 NHBE_RA NHDF Homo sapiens 3 Dermal Fibroblasts from temple / breast missing skin normal F Gingeras PromoCell NHDF BTO:0003185 NHDF NHDF-Ad Homo sapiens 3 adult dermal fibroblasts mesoderm skin normal F Stam Lonza CC-2511, CC-2511T225 BTO:0004419 NHDF-Ad NHDF-neo Homo sapiens 3 neonatal dermal fibroblasts mesoderm skin normal U Stam Lonza CC-2509 BTO:0004419 NHDF-neo NHDF 0060801.3 Homo sapiens 3 Dermal Fibroblasts from temple missing skin normal F Gingeras PromoCell C-14031 BTO:0003185 NHDF_0060801.3 NHDF 7071701.2 Homo sapiens 3 Dermal Fibroblasts from breast missing skin normal F Gingeras PromoCell C-14031 BTO:0003185 NHDF_7071701.2 NHEK Homo sapiens 3 epidermal keratinocytes ectoderm skin normal U ENCODE Lonza CC-2501 BTO:0000375 NHEK NHEM.f M2 Homo sapiens 3 Epidermal Melanocytes from two individuals, NHEM.f_M2_5071302.2 and NHEM.f_M2_6022001 from foreskin missing skin normal M Gingeras PromoCell NHEM BTO:0000847 NHEM.f M2 NHEM.f M2 5071302.2 Homo sapiens 3 Epidermal Melanocytes (foreskin) missing skin normal M Gingeras PromoCell C-14042 BTO:0000847 NHEM.f M2 (5071302.2) NHEM.f M2 6022001 Homo sapiens 3 Epidermal Melanocytes (foreskin) missing skin normal M Gingeras PromoCell C-14042 BTO:0000847 NHEM.f M2 (6022001) NHEM M2 Homo sapiens 3 Epidermal Melanocytes (adult) from two individuals, NHEM_M2_7011001.2 and NHEM_M2_7012303 from cheek / temple missing skin normal B Gingeras PromoCell NHEM BTO:0000847 NHEM M2 NHEM M2 7011001.2 Homo sapiens 3 Epidermal Melanocytes (adult) from cheek missing skin normal M Gingeras PromoCell C-14043 BTO:0000847 NHEM M2 (7011001.2) NHEM M2 7012303 Homo sapiens 3 Epidermal Melanocytes (adult) from temple missing skin normal F Gingeras PromoCell C-14043 BTO:0000847 NHEM M2 (7012303) NHLF Homo sapiens 3 lung fibroblasts endoderm lung normal U Bernstein Lonza CC-2512 BTO:0000161 (non-specific) NHLF NT2-D1 Homo sapiens 3 malignant pluripotent embryonal carcinoma (NTera-2), "The NTERA-2 cl.D1 cell line is a pluripotent human testicular embryonal carcinoma cell line derived by cloning the NTERA-2 cell line." - ATCC. (PMID: 6694356) inner cell mass testis cancer M ENCODE ATCC CRL-1973 BTO:0000946 NT2-D1 Olf neurosphere Homo sapiens 3 Human olfactory neurosphere-derived cells from mucosal biopsies Nasal biopsy normal U Crawford Alan Mackay-Sim Olf_neurosphere termId BTO:0000961 Olfactory neurosphere Osteobl Homo sapiens 3 osteoblasts (NHOst) mesoderm bone normal U Crawford Lonza CC-2538 BTO:0001593 Osteoblasts ovcar-3 Homo sapiens 3 ovarian adenocarcinoma, "the NIH: OVCAR-3 line was established in 1982 by T.C. Hamilton, et al. from the malignant ascites of a patient with progressive adenocarcinoma of the ovary." - ATCC. (PMID: 6604576) mesoderm ovary cancer F Stam ATCC HTB-161 BTO:0000812 ovcar-3 PANC-1 Homo sapiens 3 pancreatic carcinoma, (PMID: 1140870) PANC-1 was established from a pancreatic carcinoma, which was extracted via pancreatico-duodenectomy specimen from a 56-year-old Caucasian individual. Malignancy of this cell line was verified via in vitro and in vivo assays. endoderm pancreas cancer M Myers ATCC CRL-1469 BTO:0000304 PANC-1 Pancreas OC Homo sapiens 3 Primary frozen pancreas tissue from NCTC donor IDs 09-0144A (Rep B1) and 10-0021A (Rep B2) pancreas normal M Crawford NCTC 09-0144A BTO:0000988 Pancreas OC PanIsletD Homo sapiens 3 dedifferentiated human pancreatic islets from the National Disease Research Interchange (NDRI), same source as PanIslets endoderm pancreas B Crawford National Disease Research Interchange PanIsletD BTO:0000991 (non-specific) PanIsletD PanIslets Homo sapiens 3 pancreatic islets from 2 donors, the sources of these primary cells are cadavers from National Disease Research Interchange (NDRI) and another sample isolated as in Bucher, P. et al., Assessment of a novel two-component enzyme preparation for human islet isolation and transplantation. Transplantation 79, 917 (2005) endoderm pancreas normal M Crawford Refer to publication or NDRI PanIslets BTO:0000991 (non-specific) PanIslets PBDE Homo sapiens 3 peripheral blood-derived erythroblasts mesoderm blood M Farnham Dr. Peggy Farnham at USC PBDE BTO:0000574 (non-specific) PBDE PBDEFetal Homo sapiens 3 peripheral blood-derived erythroblasts from 16-19 week human fetal liver mesoderm liver normal U Farnham Bouhassira Lab FetalPBDE BTO:0000553 PBDEFetal PBMC Homo sapiens 3 peripheral blood mononuclear cells mesoderm blood M Farnham Dr. E.H. Bresnick at UW Madison PBMC BTO:0001025 PBMC PFSK-1 Homo sapiens 3 neuroectodermal cell line derived from a cerebral brain tumor, (PMID: 1316433) ectoderm brain cancer M Myers ATCC CRL-2060 BTO:0000690 (non-specific) PFSK-1 pHTE Homo sapiens 3 primary tracheal epithelial cells endoderm epithelium U Crawford Dr. Cal Cotton at Case Western Reserve University BTO:0001120 (non-specific) pHTE Pons OC Homo sapiens 3 Primary frozen pons mid-brain tissue from NICHD donor IDs 1104 (Rep B1), 602 (Rep B2), 1442 (Rep B3) pons mid-brain normal M Crawford NICHD 1104 BTO:0001101 Pons_OC PrEC Homo sapiens 3 prostate epithelial cell line epithelial prostate normal U Stam Lonza CC-2555 BTO:0002398 PrEC ProgFib Homo sapiens 3 fibroblasts, Hutchinson-Gilford progeria syndrome (cell line HGPS, HGADFN167, progeria research foundation) skin M Crawford Progeria Research Foundation HGADFN167 BTO:0001255 (non-specific) ProgFib prostate Homo sapiens 3 prostate tissue purchased for CSHL project endoderm prostate M Gingeras ATCC Missing BTO:0001129 Prostate Prostate OC Homo sapiens 3 Primary frozen prostate tissue from NICHD donor IDs 1669 (Rep B1) and 1540 (Rep B2) prostate normal M Crawford NICHD 1669 BTO:0001129 Prostate_OC Psoas muscle OC Homo sapiens 3 Primary frozen psoas muscle tissue from NICHD donor IDs 1104 (Rep B1 DNase), 602 (Rep B2 DNase), 1442 (Rep B3 DNase), 1540 (Rep B1), 1863 (Rep B2 FAIRE) psoas muscle normal B Crawford NICHD 1104 BTO:0001140 Psoas_muscle_OC Raji Homo sapiens 3 B lymphocyte, "The Raji line of lymphoblast-like cells was established by R.J.V. Pulvertaft in 1963 from a Burkitt's lymphoma of the left maxilla of an 11-year-old Black male." - ATCC. (PMID: 14086209) mesoderm blood cancer M Farnham ATCC CCl-86 BTO:0001154 Raji RCC 7860 Homo sapiens 3 renal cell adenocarcinmoma kidney cancer M Crawford ATCC CRL-1932 BTO:0000037 RCC 7860 RPMI-7951 Homo sapiens 3 Human Skin Malignant Melanoma Cells, This is a hyperdiploid human cell line with the modal chromosome number of 49, occurring in 24% of cells. Polyploid cells occurred at 22%, which is high. ectoderm skin cancer F Stam ATCC HTB-66 BTO:0003508 RPMI-7951 RPTEC Homo sapiens 3 renal proximal tubule epithelial cells epithelium normal U Stam Lonza CC-2553, CC-2553T225 BTO:0001498 RPTEC RWPE1 Homo sapiens 3 prostate epithelial prostate normal M Crawford ATCC CRL-11609 BTO:0002397 RWPE1 SAEC Homo sapiens 3 small airway epithelial cells endoderm epithelium normal U Stam Lonza CC-2547 BTO:0002022 (non-specific) SAEC SH-SY5Y Homo sapiens 3 neuroblastoma clonal subline of the neuroepithelioma cell line SK-N-SH from the 1970 bone marrow biopsy of a 4-year-old girl with metastatic neuroblastoma, trisomy of 1q ectoderm brain cancer F Farnham ATCC CC-2266 BTO:0000793 SH-SY5Y SK-N-MC Homo sapiens 3 neuroepithelioma cell line derived from a metastatic supra-orbital human brain tumor, "SK-N-MC was isolated in September of l971 and was found to have moderate dopamine - beta - hydroxylase activity as well as formaldehyde induced fluorescence indicative of intracellular catecholamines." - ATCC. (Biedler, et al. Morphology and Growth, Tumorigenicity, and Cytogenetics of Human Neuroblastoma Cells in Continuous Culture. Cancer Research 33, 2643-2652, November 1973.) ectoderm brain cancer F Myers ATCC HTB-10 BTO:0002372 (non-specific) SK-N-MC SK-N-SH RA Homo sapiens 3 neuroblastoma cell line, treatment: differentiated with retinoic acid, (Biedler, et al. Morphology and Growth, Tumorigenicity, and Cytogenetics of Human Neuroblastoma Cells in Continuous Culture. Cancer Research 33, 2643-2652, November 1973.) ectoderm brain cancer F Stam ATCC HTB-11 BTO:0002372 (non-specific) SK-N-SH (Retinoic Acid) Skeletal Muscle BC Homo sapiens 3 skeletal muscle, parental cell type to donors 01-11002 and H12817N mesoderm skeletal muscle normal B Myers BioChain CP-S12-D1234171-05_A610262 BTO:0001103 Skeletal Muscle BC SkMC Homo sapiens 3 Skeletal Striated Muscle Cells from two individuals, SkMC_9011302 SkMC_8121902.17 from M. pectoralis / Mm. intercostales missing muscle normal B Gingeras PromoCell SkMC BTO:0002916 SkMC SKMC Homo sapiens 3 skeletal muscle cells mesoderm muscle normal U Stam Lonza CC-2561 BTO:0001801 (non-specific) SkMC SkMC 8121902.17 Homo sapiens 3 Skeletal Muscle Cells from Mm. intercostales missing striated muscle normal M Gingeras PromoCell C-14060 BTO:0002916 SkMC_8121902.17 SkMC 9011302 Homo sapiens 3 Skeletal Muscle Cells from M. pectoralis missing striated muscle normal F Gingeras PromoCell C-14060 BTO:0002916 SkMC_9011302 Small intestine OC Homo sapiens 3 Primary frozen small intestine tissue from NCTC donor IDs 10-0063A (Rep B1) and 09-0143A (Rep B2) small intestine normal M Crawford NCTC 10-0063A BTO:0000651 Small intestine OC Spleen OC Homo sapiens 3 Primary frozen spleen tissue from NICHD donor IDs 1863 (Rep B1) and 4548 (Rep B2) spleen normal F Crawford NICHD 1863 BTO:0001281 Spleen_OC Stellate Homo sapiens 3 hepatic stellate cells, liver that was perfused with collagenase and sellected for hepatic stellate cells by density gradient endoderm liver normal F Crawford Dr. Steve Choi at Duke University Stellate BTO:0002316 Stellate Stomach BC Homo sapiens 3 stomach, parental cell type to donors 01-11002 and H12817N endoderm stomach normal B Myers BioChain CP-S12-D1234248-05_A808008 BTO:0001307 Stomach BC T-47D Homo sapiens 3 epithelial cell line derived from a mammary ductal carcinoma. breast cancer F Stam and Myers ATCC HTB-133 BTO:0001248 T-47D T98G Homo sapiens 3 fibroblast cell line derived from a glioblastoma multiforme. (PMID: 222778) ectoderm brain cancer M missing ATCC CRL-1690 BTO:0001583 T98G T cells CD4+ Homo sapiens 3 Parent cell line for T cells CD4+. mesoderm blood unknown B Crawford Stam Dr. David Randolph at University of Alabama, Birmingham vary BTO:0000782 T cells CD4+ TBEC Homo sapiens 3 trachea and bronchial epithelial cells from frush lung tissue provided by National Disease Research Interchange, passage 2 primary, non-immortalized cells, donor was 21 years old endoderm epithelium M Crawford National Disease Research Interchange DD009C BTO:0001389 (non-specific) TBEC Th1 Homo sapiens 3 primary Th1 T cells mesoderm blood U Stam Dr. John Stamatoyannopoulos at UW None (primary pheresis of single normal subject) BTO:0001678 Th1 Th17 Homo sapiens 3 T helper cells expressing IL-17, primary pheresis of single normal subject mesoderm blood normal B Stam Dr. John Stamatoyannopoulos at UW Th17 BTO:0002417 Th17 Th1 Wb33676984 Homo sapiens 3 Th1 cells in vivo isolation mesoderm blood normal donor is Asian, female 26 year old, primary pheresis of single normal subject F Stam Dr. John Stamatoyannopoulos at UW Wb33676984 BTO:0001678 Th1_Wb33676984 Th1 Wb54553204 Homo sapiens 3 Th1 cells in vivo isolation, donor is Caucasian, male 33 year old, primary pheresis of single normal subject mesoderm blood normal M Stam Dr. John Stamatoyannopoulos at UW Wb54553204 BTO:0001678 Th1_Wb54553204 Th2 Homo sapiens 3 primary Th2 T cells mesoderm blood U Stam Dr. John Stamatoyannopoulos at UW None (primary pheresis of single normal subject) BTO:0001679 Th2 Th2 Wb33676984 Homo sapiens 3 Th2 cells in vivo isolation, donor is Asian, female 26 year old, primary pheresis of single normal subject mesoderm blood normal F Stam Dr. John Stamatoyannopoulos at UW Wb33676984 BTO:0001679 Th2_Wb33676984 Th2 Wb54553204 Homo sapiens 3 Th2 cells in vivo isolation, donor is Caucasian, male 33 year old, primary pheresis of single normal subject mesoderm blood normal M Stam Dr. John Stamatoyannopoulos at UW Wb54553204 BTO:0001679 Th2_Wb54553204 Treg Wb78495824 Homo sapiens 3 T regulatory cells in vivo isolation mesoderm blood normal donor is Causasian, female 35 year old, primary pheresis of single normal subject F Stam Dr. John Stamatoyannopoulos at UW Wb78495824 BTO:0004520 Treg_Wb78495824 Treg Wb83319432 Homo sapiens 3 T regulatory cells in vivo isolation, donor is Caucasian, male 28 year old, primary pheresis of single normal subject mesoderm blood normal M Stam Dr. John Stamatoyannopoulos at UW Wb83319432 BTO:0004520 Treg_Wb83319432 U2OS Homo sapiens 3 osteosarcoma from the tibia of a 15 year old, J. Ponten and E. Saksela derived this line (originally 2T) in 1964 from a moderately differentiated sarcoma, viruses were not detected during co-cultivation with WI-38 cells or in CF tests against SV40, RSV or adenoviruses, mycoplasma contamination was detected and eliminated in 1972, (PMID: 6081590) mesoderm bone cancer F Farnham ATCC HTB-96 BTO:0000970 U2OS U87 Homo sapiens 3 glioblastoma, astrocytoma, (PMID: 4332744) ectoderm brain cancer M Myers ATCC HTB-14 BTO:0002036 U87 UCH-1 Homo sapiens 3 chordoma cell line ectoderm chordoma cancer M Crawford Chordoma Research Foundation BTO:0001768 UCH-1 Urothelia Homo sapiens 3 primary ureter cell culture of urothelial cells derived from a 12 year-old girl and immortalized by transfection with a temperature-sensitive SV-40 large T antigen gene urothelium normal F Crawford Dr. D Sens at University of N. Dakota Urothelia BTO:0001245 Urothelia WERI-Rb-1 Homo sapiens 3 retinoblastoma (PMID: 844036) ectoderm eye cancer F Stam ATCC HTB-169 BTO:0001178 (non-specific) WERI-Rb-1 WI-38 Homo sapiens 3 embryonic lung fibroblast cells, hTERT immortalized, includes Raf1 construct endoderm embryonic lung normal F Stam Dr. Carl Mann, SBIGeM WI-38 BTO:0001958 WI-38 3134 Mus musculus Mm Mammary cellLine Mammary M Stam Stam lab 3134 7035 3134 416B Mus musculus Mm myeloid progenitor cells, CD34+ cellLine Blood M Stam UW lab 416B 7043 416B A20 Mus musculus Mm B cell lymphoma line derived from a spontaneous reticulum cell neoplasm cellLine Blood M Stam ATCC TIB-208 7069 A20 AtT-20 Mus musculus Mm Pituitary tumor LAF1 cellLine Cortex M ENCODE ATCC CCL-89 7087 AtT-20 B-cell (CD19+) Mus musculus Mm B Cell , CD19+ primaryCells Blood M Stam Stam lab B-cell_(CD19+) 7069 B-cell_(CD19+) B-cell (CD43-) Mus musculus Mm mouse spleen B cells, CD43-,CD11b- primaryCells Blood M Stam M. Bender (FHCRC) B-cell_(CD43-) 7069 B-cell_(CD43-) BoneMarrow Mus musculus Mm Bone Marrow Tissue Bone U Ren LICR lab BoneMarrow 6943 BoneMarrow C2C12 Mus musculus Mm Myoblast cell line derived from thigh muscle of C3H mice after crush injury cellLine Skeletal Muscle F Wold Barbara Wold lab C2C12 7125 C2C12 Cerebellum Mus musculus Mm Cerebellum Tissue Cerebellum U Ren Stam Mus musculus Mm LICR lab Cerebellum 7012 Cerebellum Cerebrum Mus musculus Mm Cerebrum Tissue Cerebrum U Stam UW Lab Cerebrum Cerebrum CH12 Mus musculus Mm B-cell lymphoma (GM12878 analog) cellLine Blood F Weissman Weissman lab CH12 7069 CH12 Colon Mus musculus Mm Colon Tissue Colon U Ren LICR lab Colon 6984 Colon Cortex Mus musculus Mm Cortex Tissue Cortex U Ren LICR lab Cortex 4465 Cortex Erythrobl Mus musculus Mm Erythroblast, ter119+ cells from liver primaryCells Blood U Hardison Mitch Weiss lab Erythroblast 7079 Erythrobl ES-Bruce4 Mus musculus Mm mouse embryonic stem cells primaryCells M Ren University of California, San Diego Transgenic Core and Embryonic Stem Cell ES-Bruce4 ES-Bruce4 ES-CJ7 Mus musculus Mm ES-cells were originally isolated from 129S1/SVImJ mice by Swiatek PJ et al. in 1993 ("Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20". Swiatek PJ, Gridley T. Genes Dev. 1993 Nov,7(11):2071-84.) primaryCells U Stam Uw lab ES-CJ7 ES-CJ7 FatPad Mus musculus Mm Adipose tissue Tissue Adipose U Stam UW lab FatPad 7108 FatPad Fibroblast Mus musculus Mm Fibroblast Tissue Lung U Stam UW lab Fibroblast 6948 Fibroblast ForelimbBud Mus musculus Mm embryo forelimb buds Tissue Limb U Stam Selleri lab, Cornell ForelimbBud 3883 ForelimbBud G1E Mus musculus Mm Gata1- erythroid progenitor cellLine Blood U Hardison Mitch Weiss lab 7079 G1E G1E-ER4+E2 Mus musculus Mm Gata1 restored erythroid cells, differentiation induced by estradiol (E2) cellLine Blood U Hardison Mitch Weiss lab 7079 G1E-ER4+E2 GenitalFatPad Mus musculus Mm Genital Adipose tissue Tissue Adipose U Stam UW lab GenitalFatPad 16230 GenitalFatPad HeadlessEmbryo Mus musculus Mm Whole embryos with heads removed Tissue Embryo U Stam Selleri lab, Cornell HeadlessEmbryo 3341 HeadlessEmbryo Heart Mus musculus Mm Heart Tissue Heart U Ren LICR lab Heart 7103 Heart HindlimbBud Mus musculus Mm embryo hindlimb buds Tissue Limb U Stam Selleri lab, Cornell HindlimbBud 3891 HindlimbBud Kidney Mus musculus Mm Kidney Tissue Kidney U Stam UW lab Kidney Kidney Limb Mus musculus Mm Limb Tissue Limb U Ren LICR lab Limb 7127 Limb Liver Mus musculus Mm Liver Tissue Liver U Ren Stam Mus musculus Mm LICR lab Liver 6963 Liver Lung Mus musculus Mm Lung Tissue Lung U Ren LICR lab Lung 6948 Lung MEF Mus musculus Mm Mouse Embryonic Fibroblast primaryCells Embryonic Fibroblast U Ren LICR lab MEF 6948 MEF Megakaryo Mus musculus Mm Megakaryocyte primaryCells Blood U Hardison Mitch Weiss lab 7054 Megakaryo MEL Mus musculus Mm Leukemia (K562 analog) cellLine Blood M Weissman Stam Mus musculus Mm Weissman lab MEL MEL Mesoderm Mus musculus Mm axial somatic and lateral plate mesoderm from eviscerated headless, limbless embryos Tissue Mesoderm U Stam Selleri lab, Cornell Mesoderm 3342 Mesoderm Muscle Mus musculus Mm Muscle Tissue Blood U Hardison lab 7054 Muscle Myocyte Mus musculus Mm Myocyte cellLine Blood U Hardison Myocyte NIH-3T3 Mus musculus Mm fibroblast cellLine Blood M Stam ATCC CRL-1658 7146 NIH-3T3 OlfactBulb Mus musculus Mm Olfactory Bulb Tissue Olfactory Bulb U Ren LICR lab Olfactory Bulb 7015 OlfactBulb Pancreas Mus musculus Mm Pancreas Tissue Pancreas U Ren LICR lab Pancreas 7015 Pancreas Patski Mus musculus Mm Mouse Embryonic Kidney Fibroblast. As described in Lingenfelter et al., 1998 (Nat Genet. 1998 18:212-3) and Yang et al., 2010 (Genome Res. 2010 20:614-22), PATSKI is a female interspecific mouse fibroblast that was derived from the embryonic kidney of an M.spretus x C57BL/6J hybrid mouse such that the C57Bl/6J X chromosome (maternal) is always the inactive X. This is an adherent cell line. cellLine Kidney F Stam Dr. Christine Disteche (University of Washington) Patski 6948 Patski Placenta Mus musculus Mm Placenta Tissue Placenta U Ren LICR lab Placenta 6957 Placenta SmIntestine Mus musculus Mm Small Intestine Tissue Small Intestine U Ren LICR lab Small Intestine 6978 SmIntestine Spleen Mus musculus Mm Spleen Tissue Spleen U Ren LICR lab Spleen 7038 Spleen T-Naive Mus musculus Mm Naive T cells: CD4+, CD25- primaryCells Blood U Stam UW lab T-Naive 7060 T-Naive Testis Mus musculus Mm Testis Tissue Testis U Ren LICR lab Testis 9201 Testis Thymus Mus musculus Mm Thymus Tissue Thymus U Ren Stam Mus musculus Mm LICR lab Thymus 7037 Thymus TReg Mus musculus Mm Regulatory T cells CD4+,CD25+ primaryCells Blood U Stam UW lab TReg 7060 TReg WholeBrain Mus musculus Mm Whole Brain Tissue Brain U Stam UW lab Whole Brain 7005 WholeBrain ZhBTc4 Mus musculus Mm Undifferentiated mouse embryonic stem cells primaryCells M Stam Dr. Levasseur (University of Iowa) ZhBTc4 ZhBTc4