@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix uniprot: <http://purl.uniprot.org/uniprot/> .
@prefix taxonomy: <http://identifiers.org/taxonomy/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#>
@prefix unimod: <http://www.unimod.org/obo/unimod.obo#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix faldo: <http://biohackathon.org/resource/faldo#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix px: <https://github.com/PX-RDF/ontology/blob/master/px.owl#> .
@prefix pxd: <http://proteomecentral.proteomexchange.org/dataset/> .
@prefix jpost: <http://rdf.jpostdb.org/ontology/jpost.owl#> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix jrepo: <https://repository.jpostdb.org/entry/> .
@prefix bid: <http://rdf.jpostdb.org/bid/> .
@prefix : <http://rdf.jpostdb.org/entry/> .
    
:JPST000798	a	jpost:Project	;
	dct:title	"ATPome-wide selectivity profiling of (s)-crizotinib"	;
	rdfs:label	"ATPome-wide selectivity profiling of (s)-crizotinib"	;
	dct:identifier	"JPST000798"	;
	rdfs:seeAlso	pxd:RPXD018472	;
	rdfs:seeAlso	jrepo:JPST000123	;
	dct:description	"ATPome-wide selectivity profiling of a kinase inhibitor  (s)-crizotinib"	;
	foaf:page	jrepo:JPST000798	;
	dct:dateSubmitted	"2016-06-24"^^xsd:date	;
	dct:date	"2017-06-25"^^xsd:date	.
:JPST000798	dct:contributor	[	rdf:type	obo:MS_1002332	;
	rdf:type	foaf:Person	;
	foaf:name	"Takeshi Tomonaga"	]	.

:JPST000798	dct:contributor	[	rdf:type	obo:MS_1002037	;
	rdf:type	foaf:Person	;
	foaf:name	"Jun Adachi"	;
	vcard:organization-name	"National Institutes of Biomedical Innovation, Health and Nutrition"	]	.

bid:SMP798_1
	jpost:species	taxonomy:9606	;
	jpost:sampleType	ncit:C16403	;
	jpost:cellLine	obo:CLO_0003696	;
	rdfs:comment	"Enrichment of kinases in Hela-S3 cell lysate treated with 0 nM (non-treated with) (S)-Crizotinib, an inhibitor of 7,8-dihydro-8-oxoguanine triphosphatase MTH1"	;
	a	sio:SIO_001050	;
	a	jpost:Sample	.
bid:FRC798_1
	jpost:hasFractionationType	[
	a	jpost:PeptideFractionation	;
	rdfs:label	"Enrichment of ATP binding proteins using Thermo Scientific Pierce Kinase Enrichment Kit (Catalog number: 88310)"	;
	jpost:fractions	1	;
	jpost:replicates	1	]	;
	a	jpost:Fractionation	.
bid:ENZ798_1
	jpost:enzyme	obo:MS_1001313	;
	jpost:species	taxonomy:9606	;
	jpost:fixedModification	[	
	a	unimod:UNIMOD_4	;
	jpost:modificationSite	"C"	;
	jpost:modificationClass	jpost:JPO_025	]	;
	jpost:variableModification	[	
	a	unimod:UNIMOD_1031	;
	jpost:modificationSite	"K"	;
	jpost:modificationClass	jpost:JPO_025	]	;
	jpost:variableModification	[	
	a	unimod:UNIMOD_35	;
	jpost:modificationSite	"M"	;
	jpost:modificationClass	jpost:JPO_026	]	;
	jpost:variableModification	[	
	a	unimod:UNIMOD_259	;
	jpost:modificationSite	"K"	;
	jpost:modificationClass	jpost:JPO_031	]	;
	jpost:variableModification	[	
	a	unimod:UNIMOD_267	;
	jpost:modificationSite	"R"	;
	jpost:modificationClass	jpost:JPO_031	]	;
	a	jpost:EnzymeAndModification	.
bid:MSM798_1
	jpost:instrument	obo:MS_1001911	;
	jpost:instrumentMode	jpost:JPO_005	;
	jpost:instrumentPurpose	jpost:JPO_011	;
	jpost:quantificationPlatform	jpost:JPO_014	;
	jpost:quantificationMethod	obo:MS_1001835	;
	jpost:plexNumber	2	;
	a	jpost:MsMode	.
bid:PRF798_1
	jpost:hasSample	bid:SMP798_1	;
	jpost:hasFractionation	bid:FRC798_1	;
	jpost:hasEnzymeAndModification	bid:ENZ798_1	;
	jpost:hasMsMode	bid:MSM798_1	;
	a	jpost:Profile	.
bid:PRF798_1	jpost:hasPlex	bid:PLX798_1_1	.
bid:PLX798_1_1	rdfs:label	"SILAC-Light"	;
	dct:description	"treated with 0 nM (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_1	jpost:hasPlex	bid:PLX798_1_2	.
bid:PLX798_1_2	rdfs:label	"SILAC-Heavy"	;
	dct:description	"non-treated with (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_1	jpost:hasRawData	bid:RAW798_1_1	.
bid:RAW798_1_1	rdfs:label	"140611_AAS_1crizotinib0nM02.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:PRF798_1	jpost:hasRawData	bid:RAW798_1_2	.
bid:RAW798_1_2	rdfs:label	"140611_AAS_1crizotinib0nM01.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:SMP798_2
	jpost:species	taxonomy:9606	;
	jpost:sampleType	ncit:C16403	;
	jpost:cellLine	obo:CLO_0003696	;
	rdfs:comment	"Enrichment of kinases in Hela-S3 cell lysate treated with 10 nM (S)-Crizotinib, an inhibitor of 7,8-dihydro-8-oxoguanine triphosphatase MTH1"	;
	a	sio:SIO_001050	;
	a	jpost:Sample	.
bid:PRF798_2
	jpost:hasSample	bid:SMP798_2	;
	jpost:hasFractionation	bid:FRC798_1	;
	jpost:hasEnzymeAndModification	bid:ENZ798_1	;
	jpost:hasMsMode	bid:MSM798_1	;
	a	jpost:Profile	.
bid:PRF798_2	jpost:hasPlex	bid:PLX798_2_1	.
bid:PLX798_2_1	rdfs:label	"SILAC-Light"	;
	dct:description	"treated with 10 nM (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_2	jpost:hasPlex	bid:PLX798_2_2	.
bid:PLX798_2_2	rdfs:label	"SILAC-Heavy"	;
	dct:description	"non-treated with (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_2	jpost:hasRawData	bid:RAW798_2_1	.
bid:RAW798_2_1	rdfs:label	"140611_AAS_1crizotinib10nM02.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:PRF798_2	jpost:hasRawData	bid:RAW798_2_2	.
bid:RAW798_2_2	rdfs:label	"140611_AAS_1crizotinib10nM01.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:SMP798_3
	jpost:species	taxonomy:9606	;
	jpost:sampleType	ncit:C16403	;
	jpost:cellLine	obo:CLO_0003696	;
	rdfs:comment	"Enrichment of kinases in Hela-S3 cell lysate treated with 100 nM (S)-Crizotinib, an inhibitor of 7,8-dihydro-8-oxoguanine triphosphatase MTH1"	;
	a	sio:SIO_001050	;
	a	jpost:Sample	.
bid:PRF798_3
	jpost:hasSample	bid:SMP798_3	;
	jpost:hasFractionation	bid:FRC798_1	;
	jpost:hasEnzymeAndModification	bid:ENZ798_1	;
	jpost:hasMsMode	bid:MSM798_1	;
	a	jpost:Profile	.
bid:PRF798_3	jpost:hasPlex	bid:PLX798_3_1	.
bid:PLX798_3_1	rdfs:label	"SILAC-Light"	;
	dct:description	"treated with 100 nM (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_3	jpost:hasPlex	bid:PLX798_3_2	.
bid:PLX798_3_2	rdfs:label	"SILAC-Heavy"	;
	dct:description	"non-treated with (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_3	jpost:hasRawData	bid:RAW798_3_1	.
bid:RAW798_3_1	rdfs:label	"140611_AAS_1crizotinib100nM02.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:PRF798_3	jpost:hasRawData	bid:RAW798_3_2	.
bid:RAW798_3_2	rdfs:label	"140611_AAS_1crizotinib100nM01.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:SMP798_4
	jpost:species	taxonomy:9606	;
	jpost:sampleType	ncit:C16403	;
	jpost:cellLine	obo:CLO_0003696	;
	rdfs:comment	"Enrichment of kinases in Hela-S3 cell lysate treated with 1 µM (S)-Crizotinib, an inhibitor of 7,8-dihydro-8-oxoguanine triphosphatase MTH1"	;
	a	sio:SIO_001050	;
	a	jpost:Sample	.
bid:PRF798_4
	jpost:hasSample	bid:SMP798_4	;
	jpost:hasFractionation	bid:FRC798_1	;
	jpost:hasEnzymeAndModification	bid:ENZ798_1	;
	jpost:hasMsMode	bid:MSM798_1	;
	a	jpost:Profile	.
bid:PRF798_4	jpost:hasPlex	bid:PLX798_4_1	.
bid:PLX798_4_1	rdfs:label	"SILAC-Light"	;
	dct:description	"treated with 1 µM (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_4	jpost:hasPlex	bid:PLX798_4_2	.
bid:PLX798_4_2	rdfs:label	"SILAC-Heavy"	;
	dct:description	"non-treated with (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_4	jpost:hasRawData	bid:RAW798_4_1	.
bid:RAW798_4_1	rdfs:label	"140611_AAS_1crizotinib1uM02.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:PRF798_4	jpost:hasRawData	bid:RAW798_4_2	.
bid:RAW798_4_2	rdfs:label	"140611_AAS_1crizotinib1uM01.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:SMP798_5
	jpost:species	taxonomy:9606	;
	jpost:sampleType	ncit:C16403	;
	jpost:cellLine	obo:CLO_0003696	;
	rdfs:comment	"Enrichment of kinases in Hela-S3 cell lysate treated with 10 µM (S)-Crizotinib, an inhibitor of 7,8-dihydro-8-oxoguanine triphosphatase MTH1"	;
	a	sio:SIO_001050	;
	a	jpost:Sample	.
bid:PRF798_5
	jpost:hasSample	bid:SMP798_5	;
	jpost:hasFractionation	bid:FRC798_1	;
	jpost:hasEnzymeAndModification	bid:ENZ798_1	;
	jpost:hasMsMode	bid:MSM798_1	;
	a	jpost:Profile	.
bid:PRF798_5	jpost:hasPlex	bid:PLX798_5_1	.
bid:PLX798_5_1	rdfs:label	"SILAC-Light"	;
	dct:description	"treated with 10 µM (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_5	jpost:hasPlex	bid:PLX798_5_2	.
bid:PLX798_5_2	rdfs:label	"SILAC-Heavy"	;
	dct:description	"non-treated with (S)-Crizotinib"	;
	a	jpost:Plex	.
bid:PRF798_5	jpost:hasRawData	bid:RAW798_5_1	.
bid:RAW798_5_1	rdfs:label	"140611_AAS_1crizotinib10uM02.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
bid:PRF798_5	jpost:hasRawData	bid:RAW798_5_2	.
bid:RAW798_5_2	rdfs:label	"140611_AAS_1crizotinib10uM01.raw"	;
	foaf:page	jrepo:JPST000798	;
	a	jpost:RawData	.
