Match to: gi|8393784 Score: 310 septin 9; MLL septin-like fusion; SL3-3 integration site 1 [Mus musculus] Found in search of C:\sequest_txt\043_022704_5.txt Nominal mass (Mr): 38599; Calculated pI value: 7.67 NCBI BLAST search of gi|8393784 against nr Unformatted sequence string for pasting into other applications Taxonomy: Mus musculus Links to retrieve other entries containing this sequence from NCBI Entrez: gi|6165419 from Mus musculus gi|17980682 from Mus musculus gi|26327589 from Mus musculus Variable modifications: Acetyl (N-term),Oxidation (M),Propionamide (C),Sulphone (M) Cleavage by Trypsin: cuts C-term side of KR unless next residue is P Sequence Coverage: 15% Matched peptides shown in Bold Red 1 MADNPRDAML KQAPASRNEK APMEFGYVGI DSILEQMRRK AMKQGFEFNI 51 MVVGQSGLGK STLINTLFKS KISRKSVQPT SEERIPKTIE IKSITHDIEE 101 KGVRMKLTVI DTPGFGDHIN NENCWQPIMK FINDQYEKYL QEEVNINRKK 151 RIPDTRVHCC LYFIPATGHS LRPLDIEFMK RLSKVVNIVP VIAKADTLTL 201 EERVYFKQRI TADLLSNGID VYPQKEFDED AEDRLVNEKF REMIPFAVVG 251 SDHEYQVNGK RILGRKTKWG TIEVENTTHC EFAYLRDLLI RTHMQNIKDI 301 TSNIHFEAYR VKRLNEGNSA MANGIEKEPE AQEM
Residue Number Increasing Mass Decreasing Mass
Start - End Observed Mr(expt) Mr(calc) Delta Miss Sequence 75 - 84 581.49 1160.97 1160.25 0.72 1 KSVQPTSEER (Ions score 50) 76 - 84 517.13 1032.24 1032.08 0.17 0 SVQPTSEER (Ions score 38) 131 - 138 529.26 1056.50 1056.14 0.36 0 FINDQYEK (Ions score 44) 181 - 194 526.61 1576.80 1577.97 -1.18 2 RLSKVVNIVPVIAK Acetyl (N-term) (Ions score 30) 185 - 194 526.61 1051.20 1051.34 -0.14 0 VVNIVPVIAK (Ions score 38) 292 - 298 436.88 871.75 871.02 0.73 0 THMQNIK (Ions score 37) 299 - 310 733.79 1465.56 1465.59 -0.03 0 DITSNIHFEAYR (Ions score 78) LOCUS NP_059076 334 aa linear ROD 24-DEC-2003 DEFINITION septin 9; MLL septin-like fusion; SL3-3 integration site 1 [Mus musculus]. ACCESSION NP_059076 VERSION NP_059076.1 GI:8393784 DBSOURCE REFSEQ: accession NM_017380.1 KEYWORDS . SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. REFERENCE 1 (residues 1 to 334) AUTHORS Sorensen,A.B., Lund,A.H., Ethelberg,S., Copeland,N.G., Jenkins,N.A. and Pedersen,F.S. TITLE Sint1, a common integration site in SL3-3-induced T-cell lymphomas, harbors a putative proto-oncogene with homology to the septin gene family JOURNAL J. Virol. 74 (5), 2161-2168 (2000) PUBMED 10666245 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ250723.1. FEATURES Location/Qualifiers source 1..334 /organism="Mus musculus" /db_xref="taxon:10090" /chromosome="11" Protein 1..334 /product="septin 9" /function="putative proto-oncogene" /note="MLL septin-like fusion; SL3-3 integration site 1" Region 10..334 /region_name="Septin CDC10 and related P-loop GTPases [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms, Cytoskeleton]" /note="KOG1547" /db_xref="CDD:19335" CDS 1..334 /gene="Sept9" /coded_by="NM_017380.1:178..1182" /note="go_function: DNA binding [goid 0003677] [evidence ISS] [pmid 12466851]; go_function: DNA topoisomerase type II activity [goid 0003918] [evidence ISS] [pmid 12466851]; go_function: ATP binding [goid 0005524] [evidence ISS] [pmid 12466851]; go_process: DNA metabolism [goid 0006259] [evidence ISS] [pmid 12466851]; go_process: DNA topological change [goid 0006265] [evidence ISS] [pmid 12466851]" /db_xref="GeneID:53860" /db_xref="LocusID:53860" /db_xref="MGI:1858222"