Mascot Search Results

Protein View

Match to: gi|6754816 Score: 692
septin 2; neural precursor cell expressed, developmentally down-regulated gene 5 [Mus musculus]
Found in search of C:\sequest_txt\043_022604_4.txt

Nominal mass (Mr): 41526; Calculated pI value: 6.10
NCBI BLAST search of gi|6754816 against nr
Unformatted sequence string for pasting into other applications

Taxonomy: Mus musculus
Links to retrieve other entries containing this sequence from NCBI Entrez:
gi|1346679 from Mus musculus
gi|677953 from Mus musculus
gi|26389442 from Mus musculus

Variable modifications: Acetyl (N-term),Oxidation (M),Propionamide (C),Sulphone (M)
Cleavage by Trypsin: cuts C-term side of KR unless next residue is P
Sequence Coverage: 41%

Matched peptides shown in Bold Red

     1 MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK 
    51 STLINSLFLT DLYPERIIPG AAEKIERTVQ IEASTVEIEE RGVKLRLTVV 
   101 DTPGYGDAIN CRDCFKTIIS YIDEQFERYL HDESGLNRRH IIDNRVHCCF 
   151 YFISPFGHGL KPLDVAFMKA IHNKVNIVPV IAKADTLTLK ERERLKKRIL 
   201 DEIEEHSIKI YHLPDAESDE DEDFKEQTRL LKASIPFSVV GSNQLIEAKG 
   251 KKVRGRLYPW GVVEVENPEH NDFLKLRTML ITHMQDLQEV TQDLHYENFR 
   301 SERLKRGGRK VENEDMNKDQ ILLEKEAELR RMQEMIARMQ AQMQMQMQGG 
   351 DSDSGALGQH V

  Residue Number  Increasing Mass  Decreasing Mass 

 Start - End   Observed  Mr(expt) Mr(calc)   Delta   Miss Sequence
    51 - 66      941.70  1881.38  1882.14    -0.77     0  STLINSLFLTDLYPER  (Ions score 58)
    67 - 74      798.61   797.61   797.95    -0.34     0  IIPGAAEK  (Ions score 32)
    78 - 91      802.75  1603.49  1603.75    -0.25     0  TVQIEASTVEIEER  (Ions score 84)
   117 - 128     757.99  1513.96  1513.67     0.29     0  TIISYIDEQFER  (Ions score 76)
   129 - 138     602.62  1203.23  1203.28    -0.05     0  YLHDESGLNR  (Ions score 67)
   175 - 183     477.21   952.40   952.21     0.19     0  VNIVPVIAK  (Ions score 48)
   184 - 190     761.62   760.61   760.89    -0.28     0  ADTLTLK  (Ions score 38)
   199 - 209     664.05  1326.09  1325.48     0.60     0  ILDEIEEHSIK  (Ions score 66)
   233 - 249     881.43  1760.85  1760.02     0.83     0  ASIPFSVVGSNQLIEAK  (Ions score 67)
   310 - 325     973.93  1945.84  1946.20    -0.36     2  KVENEDMNKDQILLEK  (Ions score 83)
   332 - 338     878.61   877.60   878.07    -0.47     0  MQEMIAR  (Ions score 35)
   339 - 361    1218.36  2434.70  2435.70    -1.00     0  MQAQMQMQMQGGDSDSGALGQHV  (Ions score 45)

Error Distribution


LOCUS NP_035021 361 aa linear ROD 23-JAN-2004 DEFINITION septin 2; neural precursor cell expressed, developmentally down-regulated gene 5 [Mus musculus]. ACCESSION NP_035021 VERSION NP_035021.1 GI:6754816 DBSOURCE REFSEQ: accession NM_010891.1 KEYWORDS . SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. REFERENCE 1 AUTHORS Kinoshita,M., Field,C.M., Coughlin,M.L., Straight,A.F. and Mitchison,T.J. TITLE Self- and actin-templated assembly of Mammalian septins JOURNAL Dev. Cell 3 (6), 791-802 (2002) PUBMED 12479805 REFERENCE 2 AUTHORS Kinoshita,A., Noda,M. and Kinoshita,M. TITLE Differential localization of septins in the mouse brain JOURNAL J. Comp. Neurol. 428 (2), 223-239 (2000) PUBMED 11064363 REFERENCE 3 AUTHORS Kinoshita,A., Kinoshita,M., Akiyama,H., Tomimoto,H., Akiguchi,I., Kumar,S., Noda,M. and Kimura,J. TITLE Identification of septins in neurofibrillary tangles in Alzheimer's disease JOURNAL Am. J. Pathol. 153 (5), 1551-1560 (1998) PUBMED 9811347 REFERENCE 4 AUTHORS Kinoshita,M., Kumar,S., Mizoguchi,A., Ide,C., Kinoshita,A., Haraguchi,T., Hiraoka,Y. and Noda,M. TITLE Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures JOURNAL Genes Dev. 11, 1353-1547 (1997) COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D49382.2. FEATURES Location/Qualifiers source 1..361 /organism="Mus musculus" /db_xref="taxon:10090" /chromosome="1" Protein 1..361 /product="septin 2" /function="cytoskeletal component interacting with actin-based structures" /note="neural precursor cell expressed, developmentally down-regulated gene 5" Region 34..313 /region_name="Cell division protein" /note="GTP_CDC" /db_xref="CDD:7746" CDS 1..361 /gene="Sept2" /coded_by="NM_010891.1:54..1139" /note="go_function: GTP binding [goid 0005525] [evidence IEA]; go_function: ATP binding [goid 0005524] [evidence ISS] [pmid 12466851]; go_process: cytokinesis [goid 0016288] [evidence IEA]; go_process: cell cycle [goid 0007049] [evidence IEA]; go_process: cytokinesis [goid 0000910] [evidence IEA]" /db_xref="GeneID:18000" /db_xref="LocusID:18000" /db_xref="MGI:97298"

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