Mascot Search Results

Protein View

Match to: gi|8393784 Score: 310
septin 9; MLL septin-like fusion; SL3-3 integration site 1 [Mus musculus]
Found in search of C:\sequest_txt\043_022704_5.txt

Nominal mass (Mr): 38599; Calculated pI value: 7.67
NCBI BLAST search of gi|8393784 against nr
Unformatted sequence string for pasting into other applications

Taxonomy: Mus musculus
Links to retrieve other entries containing this sequence from NCBI Entrez:
gi|6165419 from Mus musculus
gi|17980682 from Mus musculus
gi|26327589 from Mus musculus

Variable modifications: Acetyl (N-term),Oxidation (M),Propionamide (C),Sulphone (M)
Cleavage by Trypsin: cuts C-term side of KR unless next residue is P
Sequence Coverage: 15%

Matched peptides shown in Bold Red

     1 MADNPRDAML KQAPASRNEK APMEFGYVGI DSILEQMRRK AMKQGFEFNI 
    51 MVVGQSGLGK STLINTLFKS KISRKSVQPT SEERIPKTIE IKSITHDIEE 
   101 KGVRMKLTVI DTPGFGDHIN NENCWQPIMK FINDQYEKYL QEEVNINRKK 
   151 RIPDTRVHCC LYFIPATGHS LRPLDIEFMK RLSKVVNIVP VIAKADTLTL 
   201 EERVYFKQRI TADLLSNGID VYPQKEFDED AEDRLVNEKF REMIPFAVVG 
   251 SDHEYQVNGK RILGRKTKWG TIEVENTTHC EFAYLRDLLI RTHMQNIKDI 
   301 TSNIHFEAYR VKRLNEGNSA MANGIEKEPE AQEM

  Residue Number  Increasing Mass  Decreasing Mass 

 Start - End   Observed  Mr(expt) Mr(calc)   Delta   Miss Sequence
    75 - 84      581.49  1160.97  1160.25     0.72     1  KSVQPTSEER  (Ions score 50)
    76 - 84      517.13  1032.24  1032.08     0.17     0  SVQPTSEER  (Ions score 38)
   131 - 138     529.26  1056.50  1056.14     0.36     0  FINDQYEK  (Ions score 44)
   181 - 194     526.61  1576.80  1577.97    -1.18     2  RLSKVVNIVPVIAK  Acetyl (N-term) (Ions score 30)
   185 - 194     526.61  1051.20  1051.34    -0.14     0  VVNIVPVIAK  (Ions score 38)
   292 - 298     436.88   871.75   871.02     0.73     0  THMQNIK  (Ions score 37)
   299 - 310     733.79  1465.56  1465.59    -0.03     0  DITSNIHFEAYR  (Ions score 78)

Error Distribution


LOCUS NP_059076 334 aa linear ROD 24-DEC-2003 DEFINITION septin 9; MLL septin-like fusion; SL3-3 integration site 1 [Mus musculus]. ACCESSION NP_059076 VERSION NP_059076.1 GI:8393784 DBSOURCE REFSEQ: accession NM_017380.1 KEYWORDS . SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. REFERENCE 1 (residues 1 to 334) AUTHORS Sorensen,A.B., Lund,A.H., Ethelberg,S., Copeland,N.G., Jenkins,N.A. and Pedersen,F.S. TITLE Sint1, a common integration site in SL3-3-induced T-cell lymphomas, harbors a putative proto-oncogene with homology to the septin gene family JOURNAL J. Virol. 74 (5), 2161-2168 (2000) PUBMED 10666245 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ250723.1. FEATURES Location/Qualifiers source 1..334 /organism="Mus musculus" /db_xref="taxon:10090" /chromosome="11" Protein 1..334 /product="septin 9" /function="putative proto-oncogene" /note="MLL septin-like fusion; SL3-3 integration site 1" Region 10..334 /region_name="Septin CDC10 and related P-loop GTPases [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms, Cytoskeleton]" /note="KOG1547" /db_xref="CDD:19335" CDS 1..334 /gene="Sept9" /coded_by="NM_017380.1:178..1182" /note="go_function: DNA binding [goid 0003677] [evidence ISS] [pmid 12466851]; go_function: DNA topoisomerase type II activity [goid 0003918] [evidence ISS] [pmid 12466851]; go_function: ATP binding [goid 0005524] [evidence ISS] [pmid 12466851]; go_process: DNA metabolism [goid 0006259] [evidence ISS] [pmid 12466851]; go_process: DNA topological change [goid 0006265] [evidence ISS] [pmid 12466851]" /db_xref="GeneID:53860" /db_xref="LocusID:53860" /db_xref="MGI:1858222"

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