Entity
--
e1
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane
--
--
--
csml-variable:Double
m1
0
infinite
0
--
--
e10
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cytosol
--
--
--
csml-variable:Double
m10
0
infinite
0
--
LPS:LBP
--
e11
cso30:c:Complex
cso30:i:CC_Extracellular
--
csml-variable:Double
m11
0
infinite
0
--
CD14
--
e12
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m12
0
infinite
0
--
IL-1beta
--
e13
cso30:c:mRNA
cso30:i:CC_Nucleoplasm
--
csml-variable:Double
m13
0
infinite
0
--
csml-variable:Double
m14
0
infinite
0
--
TNF-alpha
--
e15
cso30:c:Protein
cso30:i:CC_Cytosol
--
--
csml-variable:Double
m15
0
infinite
0
--
CD14 mAb
--
e16
cso30:c:Protein
cso30:i:CC_Extracellular
--
csml-variable:Double
m16
0
infinite
0
--
csml-variable:Double
m17
0
infinite
0
--
IL-1
--
e18
cso30:c:Protein
cso30:i:CC_Cytosol
--
--
csml-variable:Double
m18
0
infinite
0
--
csml-variable:Double
m19
0
infinite
0
--
--
e2
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane_ExternalSideOfPlasmaMembrane_
--
--
--
csml-variable:Double
m2
0
infinite
0
--
IL-6
--
e20
cso30:c:Protein
cso30:i:CC_Cytosol
--
--
csml-variable:Double
m20
0
infinite
0
--
csml-variable:Double
m21
0
infinite
0
--
IL-8
--
e22
cso30:c:Protein
cso30:i:CC_Cytosol
--
--
csml-variable:Double
m22
0
infinite
0
--
TNF-alpha
--
e23
cso30:c:Protein
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m23
0
infinite
0
--
TNFR
--
e24
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m24
0
infinite
0
--
TNF-alpha:TNFR
--
e25
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m25
0
infinite
0
--
csml-variable:Double
m26
0
infinite
0
--
GM-CSF
--
e27
cso30:c:Protein
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m27
0
infinite
0
--
GM-CSFR
--
e28
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m28
0
infinite
0
--
GM-CSF:GMCSFR
--
e29
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m29
0
infinite
0
--
--
e3
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
--
csml-variable:Double
m3
0
infinite
0
--
G-CSF
--
e30
cso30:c:Protein
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m30
0
infinite
0
--
GCSFR
--
e31
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m31
0
infinite
0
--
G-CSF:G-CSFR
--
e32
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m32
0
infinite
0
--
formyl peptide
--
e33
cso30:c:Protein
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m33
0
infinite
0
--
sCD14
--
e34
cso30:c:Protein
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m34
0
infinite
0
--
LPS:sCD14
--
e35
cso30:c:Complex
cso30:i:CC_Extracellular
--
csml-variable:Double
m35
0
infinite
0
--
csml-variable:Double
m36
0
infinite
0
--
LPS:CD14
--
e38
cso30:c:Complex
cso30:i:CC_Extracellular
--
csml-variable:Double
m38
0
infinite
0
--
IL-1beta
--
e39
cso30:c:Protein
cso30:i:CC_Cytosol
--
--
csml-variable:Double
m39
0
infinite
0
--
--
e4
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane_InternalSideOfPlasmaMembrane_
--
--
--
csml-variable:Double
m4
0
infinite
0
--
CD11a:CD18
--
e40
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m40
0
infinite
0
--
LPS:CD11a:CD18
--
e41
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m41
0
infinite
0
--
Cd11b:CD18
--
e42
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m42
0
infinite
0
--
LPS:CD11b:CD18
--
e43
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m43
0
infinite
0
--
CD11c:CD18
--
e44
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m44
0
infinite
0
--
LPS:CD11c:CD18
--
e45
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m45
0
infinite
0
--
csml-variable:Double
m46
0
infinite
0
--
csml-variable:Double
m47
0
infinite
0
--
p73
--
e48
cso30:c:Protein
cso30:i:CC_Extracellular
--
csml-variable:Double
m48
0
infinite
0
--
LPS:p73
--
e49
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m49
0
infinite
0
--
LPS
--
e5
cso30:c:SmallMolecule
cso30:i:CC_Extracellular
--
csml-variable:Double
m5
0
infinite
0
--
--
e50
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearEnvelopeLumen
--
--
--
csml-variable:Double
m50
0
infinite
0
--
--
e51
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearPore
--
--
--
csml-variable:Double
m51
0
infinite
0
--
--
e52
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearInnerMembrane
--
--
--
csml-variable:Double
m52
0
infinite
0
--
--
e53
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearLumen
--
--
--
csml-variable:Double
m53
0
infinite
0
--
--
e54
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearOuterMembrane
--
--
--
csml-variable:Double
m54
0
infinite
0
--
--
e55
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Nucleus
--
--
--
csml-variable:Double
m55
0
infinite
0
--
--
e56
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Nucleoplasm
--
--
--
csml-variable:Double
m56
0
infinite
0
--
--
e57
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearBody
--
--
--
csml-variable:Double
m57
0
infinite
0
--
--
e58
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Nucleolus
--
--
--
csml-variable:Double
m58
0
infinite
0
--
--
e59
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearEnvelope
--
--
--
csml-variable:Double
m59
0
infinite
0
--
LBP
--
e6
cso30:c:Protein
cso30:i:CC_Extracellular
--
csml-variable:Double
m6
0
infinite
0
--
--
e60
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Chromatin
--
--
--
csml-variable:Double
m60
0
infinite
0
--
--
e61
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearChromosome
--
--
--
csml-variable:Double
m61
0
infinite
0
--
--
e62
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearCentromere
--
--
--
csml-variable:Double
m62
0
infinite
0
--
mAb3D7
--
e63
cso30:c:Protein
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m63
0
infinite
0
--
mAb5D3
--
e64
cso30:c:Protein
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m64
0
infinite
0
--
peptidoglycan:p73
--
e65
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m65
0
infinite
0
--
peptidoglycan
--
e66
cso30:c:SmallMolecule
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m66
0
infinite
0
--
unknown recptor
--
e67
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m67
0
infinite
0
--
LPS:Unknown receptor
--
e68
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m68
0
infinite
0
--
--
e7
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cell
--
--
--
csml-variable:Double
m7
0
infinite
0
--
--
e8
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cell_WithoutCellWall_
--
--
--
csml-variable:Double
m8
0
infinite
0
--
--
e9
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cytoplasm
--
--
--
csml-variable:Double
m9
0
infinite
0
--
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c1 : 1
stoichiometry:c2 : 1
stoichiometry:c3 : 1
m5*m6*0.1
nodelay
--
0
PMID: 7542643, 1698311 CD14 has been assigned a functional role, serving as a receptor for LPS in association with LBP in which heparinized human blood cultured for 16 h with LPS resulted in TNF-alpha production, whose synthesis and release could be nearly eliminated by pre-treatment with a CD14 blocking mAb
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c27 : 1
stoichiometry:c30 : 1
stoichiometry:c31 : 1
stoichiometry:c28 : 1
m21*m38*0.1
nodelay
--
0
PMID: 7542643, 7681082 A recent report described the importance of CD14 in LPS recognition by human monocytes and alveolar macrophages, leading to the synthesis and release of TNF-alpha, IL-6, and IL-8. The LPS-induced synthesis of these cytokines could be blocked with the anti-CD14 mAb MEM-18.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c32 : 1
stoichiometry:c33 : 1
stoichiometry:c34 : 1
m23*m24*0.1
nodelay
--
0
PMID: 7542643, 1708813 TNF-alpha, GM-CSF, G-CSF, and formyl peptide have been shown to induce a twofold increase in CD14 expression.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c36 : 1
stoichiometry:c35 : 1
m25*0.1
nodelay
--
0
PMID: 7542643, 1708813 TNF-alpha, GM-CSF, G-CSF, and formyl peptide have been shown to induce a twofold increase in CD14 expression.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c37 : 1
stoichiometry:c38 : 1
stoichiometry:c39 : 1
m27*m28*0.1
nodelay
--
0
PMID: 7542643, 1708813 TNF-alpha, GM-CSF, G-CSF, and formyl peptide have been shown to induce a twofold increase in CD14 expression.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c41 : 1
stoichiometry:c40 : 1
m29*0.1
nodelay
--
0
PMID: 7542643, 1708813 TNF-alpha, GM-CSF, G-CSF, and formyl peptide have been shown to induce a twofold increase in CD14 expression.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c42 : 1
stoichiometry:c43 : 1
stoichiometry:c44 : 1
m30*m31*0.1
nodelay
--
0
PMID: 7542643, 1708813 TNF-alpha, GM-CSF, G-CSF, and formyl peptide have been shown to induce a twofold increase in CD14 expression.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c46 : 1
stoichiometry:c45 : 1
m32*0.1
nodelay
--
0
PMID: 7542643, 1708813 TNF-alpha, GM-CSF, G-CSF, and formyl peptide have been shown to induce a twofold increase in CD14 expression.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c48 : 1
stoichiometry:c47 : 1
m38*0.1
nodelay
--
0
PMID: 7542643 LPS appears to upregulate CD 14 transcripts, followed by increased expression of CDI4 protein on the cell surface.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c50 : 1
stoichiometry:c51 : 1
stoichiometry:c49 : 1
m26*m38*0.1
nodelay
--
0
PMID: 7542643 LPS appears to upregulate CD 14 transcripts, followed by increased expression of CDI4 protein on the cell surface.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c52 : 1
stoichiometry:c53 : 1
stoichiometry:c54 : 1
m5*m34*0.1
nodelay
--
0
PMID: 7542643 recombinant sCD14 produced using a baculovirus expression system was shown to specifically bind LPS
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c4 : 1
stoichiometry:c5 : 1
stoichiometry:c12 : 1
stoichiometry:c61 : 1
stoichiometry:c62 : 1
m12*m11*0.1
nodelay
--
0
PMID: 7542643, 1698311 CD14 has been assigned a functional role, serving as a receptor for LPS in association with LBP in which heparinized human blood cultured for 16 h with LPS resulted in TNF-alpha production, whose synthesis and release could be nearly eliminated by pre-treatment with a CD14 blocking mAb. Binding of erythrocyte- LPS complexes to macrophages could be inhibited by preincubation of macrophages with anti-CD14 blocking mAb.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c56 : 1
stoichiometry:c92 : 1
stoichiometry:c55 : 1
m35*0.1
nodelay
--
0
PMID: 7542643 Inhibition of LPS induced IL-6 and E-selectin expression by anti-CD14 mAb was maximal at low concentrations of LPS.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c59 : 1
stoichiometry:c11 : 1
stoichiometry:c58 : 1
m35*0.1
nodelay
--
0
PMID: 7542643 Inhibition of LPSinduced IL-6 and E-selectin expression by anti-CD14 mAb was maximal at low concentrations of LPS.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c63 : 1
stoichiometry:c6 : 1
m11*0.1
nodelay
--
0
PMID: 7542643, 2402637 In rabbit peritoneal macrophages, addition of LBP enhanced TNF-alpha production when cells were stimulated with LPS. This increase in TNF-alpha protein was accompanied by a concomitant increase in the rate and synthesis of TNF-alpha mRNA as visualized on Northern blots.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c64 : 1
stoichiometry:c66 : 1
stoichiometry:c91 : 1
stoichiometry:c65 : 1
m14*m11*0.1
nodelay
--
0
PMID: 7542643, 2402637 In rabbit peritoneal macrophages, addition of LBP enhanced TNF-alpha production when cells were stimulated with LPS. This increase in TNF-alpha protein was accompanied by a concomitant increase in the rate and synthesis of TNF-alpha mRNA as visualized on Northern blots. PMID: 7542643, 1698311 CD14 has been assigned a functional role, serving as a receptor for LPS in association with LBP in which heparinized human blood cultured for 16 h with LPS resulted in TNF-alpha production, whose synthesis and release could be nearly eliminated by pre-treatment with a CD14 blocking mAb
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c68 : 1
stoichiometry:c67 : 1
m11*0.1
nodelay
--
0
PMID: 7542643, 1607653 when LBP was added during LPS stimulation, macrophages responded with a more rapid induction of TNF-alpha and IL-lbeta mRNA, higher steady state mRNA levels, and increased mRNA stability which was shown to correlate with increased TNF-alpha and IL-lbeta protein.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c69 : 1
stoichiometry:c71 : 1
stoichiometry:c70 : 1
m13*m11*0.1
nodelay
--
0
PMID: 7542643, 1607653 when LBP was added during LPS stimulation, macrophages responded with a more rapid induction of TNF-alpha and IL-lbeta mRNA, higher steady state mRNA levels, and increased mRNA stability which was shown to correlate with increased TNF-alpha and IL-lbeta protein.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c72 : 1
stoichiometry:c73 : 1
stoichiometry:c74 : 1
m40*m5*0.1
nodelay
--
0
PMID: 7542643 All three members of the CD18 family (CDlla/CD18, CDllb/CD18, and CD 1Ic/CD 18) are capable of binding LPS.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c75 : 1
stoichiometry:c76 : 1
stoichiometry:c77 : 1
m5*m42*0.1
nodelay
--
0
PMID: 7542643 All three members of the CD18 family (CDlla/CD18, CDllb/CD18, and CD 1Ic/CD 18) are capable of binding LPS.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c78 : 1
stoichiometry:c79 : 1
stoichiometry:c80 : 1
m5*m44*0.1
nodelay
--
0
PMID: 7542643 All three members of the CD18 family (CDlla/CD18, CDllb/CD18, and CD 1Ic/CD 18) are capable of binding LPS.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c83 : 1
stoichiometry:c90 : 1
stoichiometry:c81 : 1
m38*0.1
nodelay
--
0
PMID: 7542643, 1717586 LPS treatment has been shown to induce a rapid upregulation of CDllb/ CD 18 expression on human neutrophils, believed to be mediated by CD14, since anti-CD14 mAb specifically inhibited LPS-induced CDllb/CD18 expression (Lynn et al., 1991).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c8 : 1
stoichiometry:c7 : 1
m38*0.1
nodelay
--
0
PMID: 7542643, 1698311 CD14 has been assigned a functional role, serving as a receptor for LPS in association with LBP in which heparinized human blood cultured for 16 h with LPS resulted in TNF-alpha production, whose synthesis and release could be nearly eliminated by pre-treatment with a CD14 blocking mAb
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c84 : 1
stoichiometry:c89 : 1
stoichiometry:c82 : 1
m38*0.1
nodelay
--
0
PMID: 7542643, 1717586 LPS treatment has been shown to induce a rapid upregulation of CDllb/ CD 18 expression on human neutrophils, believed to be mediated by CD14, since anti-CD14 mAb specifically inhibited LPS-induced CDllb/CD18 expression (Lynn et al., 1991).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c85 : 1
stoichiometry:c86 : 1
stoichiometry:c88 : 1
stoichiometry:c99 : 1
stoichiometry:c87 : 1
m5*m48*0.1
nodelay
--
0
PMID: 7542643, 2456339 one of the most well-characterized LPS receptors in addition to CD18 and CD14, is the 73 kDa (80 kDa) receptor. PMID: 7542643 Two mAb were obtained from a series of clones, designated mAb 3D7 and mAb 5D3 were able to inhibit the interaction of LPS with the 73 kDa LPS receptor in a dose-dependent manner, reflecting specificity.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c93 : 1
stoichiometry:c95 : 1
stoichiometry:c94 : 1
m48*m66*0.1
nodelay
--
0
PMID: 7542643, 2002021 The p73 receptor has been demonstrated to bind soluble peptidoglycan on mouse B lymphocytes.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c96 : 1
stoichiometry:c97 : 1
stoichiometry:c98 : 1
m5*m67*0.1
nodelay
--
0
PMID: 7542643, 7690343 A 38 kDa cell surface protein displaying affinity for LPS was identified on mouse lymphocytes, macrophages, splenocytes, J774.1 cells and 70Z/3 cells using 125I-ASD-LPS.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c10 : 1
stoichiometry:c9 : 1
m33*0.1
nodelay
--
0
PMID: 7542643, 1708813 TNF-alpha, GM-CSF, G-CSF, and formyl peptide have been shown to induce a twofold increase in CD14 expression.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c15 : 1
stoichiometry:c14 : 1
m38*0.1
nodelay
--
0
PMID: 7542643, 1376258 CD14 plays an important role in macrophage production of IL-1 in response to LPS. The LPS-induced synthesis of these cytokines could be blocked with the anti-CD14 mAb MEM-18.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c16 : 1
stoichiometry:c18 : 1
stoichiometry:c19 : 1
stoichiometry:c17 : 1
m17*m38*0.1
nodelay
--
0
PMID: 7542643, 1376258 CD14 plays an important role in macrophage production of IL-1 in response to LPS. The LPS-induced synthesis of these cytokines could be blocked with the anti-CD14 mAb MEM-18.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c21 : 1
stoichiometry:c13 : 1
stoichiometry:c20 : 1
m38*0.1
nodelay
--
0
PMID: 7542643, 7681082 A recent report described the importance of CD14 in LPS recognition by human monocytes and alveolar macrophages, leading to the synthesis and release of TNF-alpha, IL-6, and IL-8. The LPS-induced synthesis of these cytokines could be blocked with the anti-CD14 mAb MEM-18. PMID: 7542643 Inhibition of LPS induced IL-6 and E-selectin expression by anti-CD14 mAb was maximal at low concentrations of LPS.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c29 : 1
stoichiometry:c26 : 1
m38*0.1
nodelay
--
0
PMID: 7542643, 7681082 A recent report described the importance of CD14 in LPS recognition by human monocytes and alveolar macrophages, leading to the synthesis and release of TNF-alpha, IL-6, and IL-8. The LPS-induced synthesis of these cytokines could be blocked with the anti-CD14 mAb MEM-18.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c22 : 1
stoichiometry:c25 : 1
stoichiometry:c24 : 1
stoichiometry:c23 : 1
m19*m38*0.1
nodelay
--
0
PMID: 7542643, 7681082 A recent report described the importance of CD14 in LPS recognition by human monocytes and alveolar macrophages, leading to the synthesis and release of TNF-alpha, IL-6, and IL-8. The LPS-induced synthesis of these cytokines could be blocked with the anti-CD14 mAb MEM-18.
cso30:c:InputAssociation
threshold
--
0
1,
--
cso30:c:InputInhibitor
threshold
--
0
1,
--
cso30:c:InputInhibitor
threshold
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0
1,
--
cso30:c:InputInhibitor
threshold
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cso30:c:OutputProcess
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cso30:c:InputAssociation
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputInhibitor
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cso30:c:InputAssociation
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cso30:c:InputAssociation
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:OutputProcess
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputInhibitor
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cso30:c:InputAssociation
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cso30:c:InputAssociation
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cso30:c:OutputProcess
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cso30:c:InputInhibitor
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cso30:c:InputAssociation
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cso30:c:InputAssociation
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cso30:c:InputProcess
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cso30:c:InputProcess
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cso30:c:InputProcess
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cso30:c:InputAssociation
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cso30:c:InputProcess
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cso30:c:InputAssociation
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cso30:c:OutputProcess
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cso30:c:InputAssociation
threshold
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cso30:c:OutputProcess
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputProcess
threshold
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cso30:c:OutputProcess
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:OutputProcess
threshold
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cso30:c:InputAssociation
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cso30:c:OutputProcess
threshold
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cso30:c:OutputProcess
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:OutputProcess
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputAssociation
threshold
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cso30:c:InputProcess
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cso30:c:InputProcess
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cso30:c:OutputProcess
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cso30:c:InputProcess
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cso30:c:InputProcess
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cso30:c:OutputProcess
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cso30:c:InputProcess
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cso30:c:InputProcess
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cso30:c:InputAssociation
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cso30:c:OutputProcess
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cso30:c:OutputProcess
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cso30:c:OutputProcess
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cso30:c:InputAssociation
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cso30:c:InputAssociation
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cso30:c:InputProcess
threshold
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cso30:c:InputProcess
threshold
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cso30:c:OutputProcess
threshold
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cso30:c:InputInhibitor
threshold
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cso30:c:InputInhibitor
threshold
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cso30:c:InputInhibitor
threshold
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0
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cso30:c:InputInhibitor
threshold
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cso30:c:InputInhibitor
threshold
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0
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cso30:c:InputProcess
threshold
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0
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cso30:c:OutputProcess
threshold
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0
1,
--
cso30:c:InputProcess
threshold
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0
1,
--
cso30:c:InputProcess
threshold
--
0
1,
--
cso30:c:OutputProcess
threshold
--
0
1,
--