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Indirect
PMID: 18407061
Vacuolar escape and listeriolysin O toxin were required for NALP3 inflammasome activation by Listeria monocytogenes.
Indirect
PMID: 18407061
Bacillus anthracis uses anthrax lethal toxin to activate a NALP1b inflammasome.
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
PMID; 18407061
Infection with M. tuberculosis triggers IPAF inflammasome including the adaptor ASC and caspase-1 (Casp-1).
Indirect
PMID: 18407061, 17126540
IPAF and ASC have been previously associated with inflammasome activation by the Gram-negative bacteria Salmonella typhimurium, Shigella flexneri, and Pseudomonas aeruginosa, which use their type III secretion system to inject IPAF activators such as flagellin in the cytosol of macrophages.
Indirect
PMID; 18407061
Infection with M. tuberculosis triggers IPAF inflammasome including the adaptor ASC and caspase-1 (Casp-1).
Indirect
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
Indirect
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
Indirect
PMID: 18407061
Inflammasome activation results in IL-1beta processing and release of IL-1beta that is followed by the engagement of its receptor (IL-1R).
PMID: 18407061
Inflammasome activation results in IL-1beta processing and release of IL-1beta that is followed by the engagement of its receptor (IL-1R).
PMID: 18407061
Inflammasome activation results in IL-1beta processing and release of IL-1beta that is followed by the engagement of its receptor (IL-1R).
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
PMID; 18407061
Infection with M. tuberculosis triggers IPAF inflammasome including the adaptor ASC and caspase-1 (Casp-1).
Indirect
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
Indirect
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
Indirect
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
Indirect
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
PMID: 18407061
The NLR family members NALP3, NAIP5, or IPAF and the adaptor ASC are involved in caspase-1 activation in response to bacterial infection, triggering the processing and maturation of IL-1beta and IL-18 cytokines.
PMID; 18407061
Infection with M. tuberculosis triggers IPAF inflammasome including the adaptor ASC and caspase-1 (Casp-1).
Indirect
PMID: 18407061
IL-1beta is known to activate PI3K, and it is tempting to speculate that the IL-1R signaling pathway and phagosome maturation pathway may converge at PI3K activation to promote PI3P generation.