Entity
MMP-9
--
G010279
cso30:c:mRNA
cso30:i:CC_CellComponent
--
csml-variable:Double
m93262
10
infinite
0
TRANSFAC | G010279 |
--
TNF-alpha
--
MO000000289
cso30:c:Protein
cso30:i:CC_CellComponent
--
--
csml-variable:Double
m230
10
infinite
0
InterPro | IPR003636 |
TRANSPATH | MO000000289 |
--
--
e1
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane
--
--
--
csml-variable:Double
m1
0
infinite
0
--
--
e10
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cytosol
--
--
--
csml-variable:Double
m10
0
infinite
0
--
MIP-1beta
--
e11
cso30:c:mRNA
cso30:i:CC_Nucleoplasm
--
csml-variable:Double
m11
0
infinite
0
--
csml-variable:Double
m12
10
infinite
0
Affymetrix | 128677_at |
Ensembl | ENSMUSG00000030669 |
MGD | Calca |
Proteome | HumanPSD/Calca |
RefSeq | NM_001033954 |
TRANSFAC | G005845 |
Unigene | Mm.4361 |
--
XGXXPG
--
e15
cso30:c:SmallMolecule
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m15
0
infinite
0
--
XGXXPG: EBP
--
e16
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m16
0
infinite
0
--
csml-variable:Double
m17
0
infinite
0
--
XGXXPG: EBP: PPCA
--
e18
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m18
0
infinite
0
--
XGXXPG: EBP: PPCA: NEU1
--
e19
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m19
0
infinite
0
--
--
e2
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane_ExternalSideOfPlasmaMembrane_
--
--
--
csml-variable:Double
m2
0
infinite
0
--
csml-variable:Double
m22
0
infinite
0
--
hyaluronan fragment
--
e23
cso30:c:SmallMolecule
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m23
0
infinite
0
--
hyaluronan fragment: CD44
--
e24
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m24
0
infinite
0
--
KC
--
e25
cso30:c:Protein
cso30:i:CC_Cytosol
--
--
csml-variable:Double
m25
0
infinite
0
--
fibronectin fragmant
--
e27
cso30:c:SmallMolecule
cso30:i:CC_Extracellular
--
--
csml-variable:Double
m27
0
infinite
0
--
fibronectin fragment recptor
--
e28
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m28
0
infinite
0
--
fibronectin fragmant : fibronectin fragment recptor
--
e29
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m29
0
infinite
0
--
--
e3
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
--
csml-variable:Double
m3
0
infinite
0
--
SIKVAV receptor
--
e30
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m30
0
infinite
0
--
SIKVAV :SIKVAV receptor
--
e31
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m31
0
infinite
0
--
csml-variable:Double
m32
0
infinite
0
--
ASKVKV receptor
--
e33
cso30:c:Protein
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
--
csml-variable:Double
m33
0
infinite
0
--
ASKVKV: ASKVKV receptor
--
e34
cso30:c:Complex
cso30:i:CC_PlasmaMembrane_IntegralToPlasmaMembrane_
--
csml-variable:Double
m34
0
infinite
0
--
csml-variable:Double
m35
10
infinite
0
Affymetrix | 1301_s_at |
BRENDA | 3.4.24.80 |
Ensembl | ENSG00000157227 |
HGNC | MMP14 |
InterPro | IPR006026 |
OMIM | 600754 |
PROSITE | PS00142 |
Proteome | HumanPSD/MMP14 |
RefSeq | NM_004995 |
TRANSPATH | MO000003223 |
Unigene | Hs.2399 |
UniProt | P50281 |
--
TNFR-II
--
e36
cso30:c:mRNA
cso30:i:CC_Nucleoplasm
--
--
csml-variable:Double
m36
0
infinite
0
--
VGVAPG
--
e37
cso30:c:SmallMolecule
cso30:i:CC_Cytosol
--
csml-variable:Double
m37
0
infinite
0
--
csml-variable:Double
m40
0
infinite
0
--
--
e4
cso30:c:EntityBiologicalCompartment
cso30:i:CC_PlasmaMembrane_InternalSideOfPlasmaMembrane_
--
--
--
csml-variable:Double
m4
0
infinite
0
--
csml-variable:Double
m5
0
infinite
0
--
--
e50
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearEnvelopeLumen
--
--
--
csml-variable:Double
m50
0
infinite
0
--
--
e51
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearPore
--
--
--
csml-variable:Double
m51
0
infinite
0
--
--
e52
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearInnerMembrane
--
--
--
csml-variable:Double
m52
0
infinite
0
--
--
e53
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearLumen
--
--
--
csml-variable:Double
m53
0
infinite
0
--
--
e54
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearOuterMembrane
--
--
--
csml-variable:Double
m54
0
infinite
0
--
--
e55
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Nucleus
--
--
--
csml-variable:Double
m55
0
infinite
0
--
--
e56
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Nucleoplasm
--
--
--
csml-variable:Double
m56
0
infinite
0
--
--
e57
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearBody
--
--
--
csml-variable:Double
m57
0
infinite
0
--
--
e58
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Nucleolus
--
--
--
csml-variable:Double
m58
0
infinite
0
--
--
e59
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearEnvelope
--
--
--
csml-variable:Double
m59
0
infinite
0
--
csml-variable:Double
m6
10
infinite
0
Affymetrix | 102424_at |
Ensembl | ENSMUSG00000000982 |
MGD | Ccl3 |
Proteome | HumanPSD/Ccl3 |
RefSeq | NM_011337 |
TRANSFAC | G001238 |
Unigene | Mm.1282 |
--
--
e60
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Chromatin
--
--
--
csml-variable:Double
m60
0
infinite
0
--
--
e61
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearChromosome
--
--
--
csml-variable:Double
m61
0
infinite
0
--
--
e62
cso30:c:EntityBiologicalCompartment
cso30:i:CC_NuclearCentromere
--
--
--
csml-variable:Double
m62
0
infinite
0
--
--
e7
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cell
--
--
--
csml-variable:Double
m7
0
infinite
0
--
--
e8
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cell_WithoutCellWall_
--
--
--
csml-variable:Double
m8
0
infinite
0
--
--
e9
cso30:c:EntityBiologicalCompartment
cso30:i:CC_Cytoplasm
--
--
--
csml-variable:Double
m9
0
infinite
0
--
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c33 : 1
stoichiometry:c19 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c13 : 1
stoichiometry:c14 : 1
stoichiometry:c15 : 1
m16*m17*0.1
nodelay
--
0
PMID: 18243041 EBP complexes with the 55-kDa protective protein-cathepsin A (PPCA) and the 61-kDa neuraminidase (Neu-1) on the cell surface.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c16 : 1
stoichiometry:c18 : 1
stoichiometry:c17 : 1
m18*m20*0.1
nodelay
--
0
PMID: 18243041 EBP complexes with the 55-kDa protective protein-cathepsin A (PPCA) and the 61-kDa neuraminidase (Neu-1) on the cell surface.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c38 : 1
stoichiometry:c24 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c68 : 1
stoichiometry:c52 : 1
m19*0.1
nodelay
--
0
PMID: 18243041 In these same studies, stimulation of T cells with elastin peptides resulted in interferon gamma release that correlated with the severity of emphysema.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c21 : 1
stoichiometry:c20 : 1
stoichiometry:c22 : 1
m23*m399*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages. PMID: 18243041 Initial studies indicated that signaling from hyaluronan degradation products involves CD44 exclusively.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c26 : 1
stoichiometry:c44 : 1
stoichiometry:c25 : 1
m12*m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c31 : 1
stoichiometry:c45 : 1
stoichiometry:c27 : 1
m13*m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c32 : 1
stoichiometry:c46 : 1
stoichiometry:c28 : 1
m14*m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c39 : 1
stoichiometry:c29 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c40 : 1
stoichiometry:c30 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c34 : 1
stoichiometry:c23 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c50 : 1
stoichiometry:c49 : 1
stoichiometry:c51 : 1
m27*m28*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c53 : 1
stoichiometry:c67 : 1
stoichiometry:c47 : 1
m93423*m19*0.1
nodelay
--
0
PMID: 18243041 In these same studies, stimulation of T cells with elastin peptides resulted in interferon gamma release that correlated with the severity of emphysema.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c63 : 1
stoichiometry:c55 : 1
m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
p23
p23
cso30:i:ME_Translation
cso30:i:CC_Nucleoplasm
--
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c57 : 1
stoichiometry:c64 : 1
stoichiometry:c56 : 1
m93262*m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
p24
p24
cso30:i:ME_Translation
cso30:i:CC_Cytosol
--
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c60 : 1
stoichiometry:c62 : 1
stoichiometry:c59 : 1
m102788*m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c61 : 1
stoichiometry:c58 : 1
m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c66 : 1
stoichiometry:c48 : 1
m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c72 : 1
stoichiometry:c69 : 1
m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c75 : 1
stoichiometry:c77 : 1
m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c65 : 1
stoichiometry:c73 : 1
stoichiometry:c54 : 1
m21*m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c35 : 1
stoichiometry:c4 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
p30
p30
cso30:i:ME_Translation
cso30:i:CC_Cytosol
--
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c71 : 1
stoichiometry:c74 : 1
stoichiometry:c70 : 1
m93248*m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
p31
p31
cso30:i:ME_Translation
cso30:i:CC_Cytosol
--
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c78 : 1
stoichiometry:c79 : 1
stoichiometry:c76 : 1
m93309*m29*0.1
nodelay
--
0
PMID: 18243041, 1740645, 7696347, 17327485 Several fibronectin-derived fragments increase monocyte/macrophage secretion of proteases (e.g., MMP-9/gelatinase B, MMP-12/macrophage elastase) and pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNFalpha).
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c84 : 1
stoichiometry:c80 : 1
m31*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c85 : 1
stoichiometry:c86 : 1
m31*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c81 : 1
stoichiometry:c82 : 1
stoichiometry:c83 : 1
m22*m30*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c87 : 1
stoichiometry:c88 : 1
stoichiometry:c89 : 1
m32*m33*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c91 : 1
stoichiometry:c90 : 1
m34*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c93 : 1
stoichiometry:c92 : 1
m34*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c95 : 1
stoichiometry:c96 : 1
stoichiometry:c94 : 1
m93747*m34*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c97 : 1
stoichiometry:c98 : 1
m93262*m34*0.1
nodelay
--
0
PMID: 18243041, 12817023, 7737965, 12817023 Peptides containing the SIKVAV sequence of laminin-111 induce the expression of MMP-9 and urokinase-type plaminogen activator (uPA) by monocytes/macrophages, and a similar peptide (ASKVKV) derived from laminin-511 induces MMP-9 and MMP-14/MT1-MMP production by monocytes and macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c36 : 1
stoichiometry:c5 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c100 : 1
stoichiometry:c99 : 1
m34*0.1
nodelay
--
0
PMID: 18243041, 15661925 Additional studies using microarray analysis indicated that this laminin alpha5-derived peptide up-regulates many genes, including the pro-inflammatory cytokine TNFalpha and one of its receptors, TNFR-II.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c102 : 1
stoichiometry:c101 : 1
m34*0.1
nodelay
--
0
PMID: 18243041, 15661925 Additional studies using microarray analysis indicated that this laminin alpha5-derived peptide up-regulates many genes, including the pro-inflammatory cytokine TNFalpha and one of its receptors, TNFR-II.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c103 : 1
stoichiometry:c105 : 1
stoichiometry:c104 : 1
m38*m37*0.1
nodelay
--
0
PMID: 18243041, 15860743 Using melanoma cells as the target cell and induction of IL-1beta as the readout Debret et al. found that VGVAPG induced NF-kappaB translocation and DNA binding.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c106 : 1
stoichiometry:c107 : 1
stoichiometry:c109 : 1
stoichiometry:c108 : 1
m39*m5*m37*0.1
nodelay
--
0
--
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c37 : 1
stoichiometry:c6 : 1
m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c7 : 1
stoichiometry:c41 : 1
stoichiometry:c1 : 1
m6*m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c8 : 1
stoichiometry:c42 : 1
stoichiometry:c2 : 1
m11*m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c9 : 1
stoichiometry:c43 : 1
stoichiometry:c3 : 1
m93710*m24*0.1
nodelay
--
0
PMID: 18243041, 10201943, 11000131, 8941660 low molecular weight fragments of hyaluronan increase the expression of matrix metalloproteinase (MMP)-12, plasminogen activator inhibitor (PAI)-1 and stimulate the production of several cytokines, including MIP-1alpha, MIP-1beta, MCP-1, KC, IL-8, and IL-12 by macrophages.
--
and
mass
coefficient1:0.1
coefficient2:1.0
stoichiometry:c10 : 1
stoichiometry:c11 : 1
stoichiometry:c12 : 1
m15*m15253*0.1
nodelay
--
0
PMID: 18243041 The identity of this receptor protein, commonly called the elastin-binding protein (EBP), has been established as an enzymatically inactive, alternatively spliced variant of beta-galactosidase. PMID: 18243041 This protein binds the X-Gly-X-X-Pro-Gly (XGXXPG) motif in ECM proteins, such as elastin, laminins, collagen type IV, and fibrillin-1.
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