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-0.2670194114780191, -0.1938807756273343, 0.1541682514307271, -0.335801503386543, 0.8890701118733351, 101.94580947006656)" width="7" style="fill:url(#color100);stroke:none;" height="22.452"/> </g> <g> <path d="M16.997,151.507l2-3.465l-6.063-3.5l-2,3.464L16.997,151.507z M12.997,158.435l2-3.464l-6.063-3.5 l-2,3.464L12.997,158.435z" style="fill:url(#color100);stroke:none;" transform="matrix( 0.308336502861454, 0, 0, 0.3877615512546687, 7.8921012658135385, 0.9999999365591632)"/> </g> </g> <g> <path d="M136.028,82.846h4.472v-7h-4.472V82.846z M126.028,82.846h5v-7h-5V82.846z M116.028,82.846h5v-7h-5V82.846z M106.028,82.846h5v-7h-5V82.846z" style="fill:url(#color100);stroke:none;" transform="matrix( 0.308336502861454, 0, 0, 0.3877615512546687, 7.8921012658135385, 0.9999999365591632)"/> </g> </g> </svg> PMID: 18031244, 12816876 Others had shown that administration of LPS (lipopolysaccharide), an exogenous TLR4 agonist, promoted disease in rabbits and mice. PMID: 18031244, 16267105, 16025156, 11781369 Other possibilities include HMGB1 (high-mobility group B1), biglycan, hyaluronic acid fragments, necrotic cells and SAA (serum amyloid A) [31–36]. All of these have been shown to be TLR2 agonists in vitro. PMID: 18031244, 16267105, 16025156, 11781369 Other possibilities include HMGB1 (high-mobility group B1), biglycan, hyaluronic acid fragments, necrotic cells and SAA (serum amyloid A) [31–36]. All of these have been shown to be TLR2 agonists in vitro. PMID: 18031244, 16267105, 16025156, 11781369 Other possibilities include HMGB1 (high-mobility group B1), biglycan, hyaluronic acid fragments, necrotic cells and SAA (serum amyloid A) [31–36]. All of these have been shown to be TLR2 agonists in vitro. PMID: 18031244, 16267105, 16025156, 11781369 Other possibilities include HMGB1 (high-mobility group B1), biglycan, hyaluronic acid fragments, necrotic cells and SAA (serum amyloid A) [31–36]. All of these have been shown to be TLR2 agonists in vitro. PMID: 18031244 the proatherogenic TLR2 responses to the defined synthetic exogenous agonist Pam3 CSK4 are mediated at least in part by BMDC, which can include lymphocytes, monocytes/macrophages and dendritic cells.